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Author: World Health Organization Publisher: World Health Organization ISBN: 9240064419 Category : Medical Languages : en Pages : 62
Book Description
The document presents outcome of a WHO multi-centre study (2020–2022) performed by eight laboratories in different WHO regions and the WHO expert consultations that made recommendations to WHO on insecticide discriminating concentrations (DCs) for monitoring resistance in sand fly vectors of leishmaniases. It describes use of the WHO bottle bioassay as a new method for testing susceptibility of sand flies to insecticides that are not suitable for impregnation on filter papers and makes recommendations to WHO on monitoring of insecticide resistance in field populations of sand flies. It also proposes further research to test the new DCs for sand flies in other settings and conditions and to collect evidence from the national disease control programmes and share them with WHO for further assessment and revision of the DCs if required. The current edition of the WHO manual for monitoring insecticide resistance in mosquito vectors and selecting appropriate interventions will be revised using the recommendations made to WHO including for the new DCs for sand flies. The report will be useful to the national vector-borne disease control programmes and the research community for resistance monitoring, and to academia, the pesticide regulatory agencies and the pesticide industry for further innovation in this area and to address the research questions. Please send your suggestions and comments to [email protected] indicating the title of the report and the relevant section and page.
Author: World Health Organization Publisher: World Health Organization ISBN: 9240064419 Category : Medical Languages : en Pages : 62
Book Description
The document presents outcome of a WHO multi-centre study (2020–2022) performed by eight laboratories in different WHO regions and the WHO expert consultations that made recommendations to WHO on insecticide discriminating concentrations (DCs) for monitoring resistance in sand fly vectors of leishmaniases. It describes use of the WHO bottle bioassay as a new method for testing susceptibility of sand flies to insecticides that are not suitable for impregnation on filter papers and makes recommendations to WHO on monitoring of insecticide resistance in field populations of sand flies. It also proposes further research to test the new DCs for sand flies in other settings and conditions and to collect evidence from the national disease control programmes and share them with WHO for further assessment and revision of the DCs if required. The current edition of the WHO manual for monitoring insecticide resistance in mosquito vectors and selecting appropriate interventions will be revised using the recommendations made to WHO including for the new DCs for sand flies. The report will be useful to the national vector-borne disease control programmes and the research community for resistance monitoring, and to academia, the pesticide regulatory agencies and the pesticide industry for further innovation in this area and to address the research questions. Please send your suggestions and comments to [email protected] indicating the title of the report and the relevant section and page.
Author: World Health Organization Publisher: World Health Organization ISBN: 9240074600 Category : Medical Languages : en Pages : 32
Book Description
This document contains the standard operating procedure (SOP) for evaluating the susceptibility of adult sand fly vectors (Phlebotomus spp. and Lutzomyia longipalpis) to insecticides in WHO bottle bioassays. Some species of sand flies are vectors of leishmaniases. The SOP includes instructions on preparing materials, exposing sand flies, and recording and interpreting test results. This procedure should be followed to test the susceptibility of sand flies to insecticides that are unstable and/or cannot be impregnated on usual Whatman No. 1 filter papers. This SOP will fulfil the long-awaited need of vector-borne disease control programmes in health ministries in countries endemic for or at risk of visceral and cutaneous leishmaniasis, researchers and the pesticide industry to monitor insecticide resistance in wild populations of sand fly vectors. It can be adapted to determine discriminating concentrations of new insecticide compounds with susceptible strains of sand fly vectors in laboratories.
Author: Publisher: World Health Organization ISBN: 9240045201 Category : Medical Languages : en Pages : 109
Book Description
The document provides an up-to-date recommendations made to WHO by the experts of WHO consultations on discriminating concentrations of insecticides for monitoring resistance in adult mosquito vectors. It is an outcome of a WHO multi-centre study (2017–2021) performed by 23 laboratories in different regions and the WHO expert consultations that made recommendations to WHO on insecticide discriminating concentrations for monitoring resistance in Anopheles and Aedes spp. The document describes a new WHO bottle bioassay method for testing susceptibility of mosquitoes to insecticides that are not suitable for impregnation on filter papers and makes recommendations for future scientific research on development of methods and procedures for testing resistance against insecticides with new, novel or distinct modes of action. Making use of the recommendations made to WHO by the experts, WHO will soon update current WHO test methods and procedures and publish standard operating procedures for testing insecticide resistance in mosquitoes, which in turn will be useful to the national vector-borne disease control programmes, in particular the entomological surveillance units, and the research community for monitoring insecticide resistance in field populations of mosquito vectors of disease. The document will also be useful to academia, the pesticide regulatory agencies and the pesticide industry for further innovation in this area and to address the research questions.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309168309 Category : Medical Languages : en Pages : 333
Book Description
The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.
Author: Farhat Afrin Publisher: BoD – Books on Demand ISBN: 1789841011 Category : Medical Languages : en Pages : 234
Book Description
Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.
Author: World Health Organization Publisher: World Health Organization ISBN: 9241549653 Category : Medical Languages : en Pages : 242
Book Description
This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes. It is an extension of earlier guidance and teaching material published by the World Health Organization (WHO): Handbook for integrated vector management Monitoring and evaluation indicators for integrated vector management Guidance on policy-making for integrated vector management and Core structure for training curricula on integrated vector management. The toolkit provides the technical detail required to plan implement monitor and evaluate an IVM approach. IVM can be used when the aim is to control or eliminate vector-borne diseases and can also contribute to insecticide resistance management. This toolkit provides information on where vector-borne diseases are endemic and what interventions should be used presenting case studies on IVM as well as relevant guidance documents for reference. The diseases that are the focus of this toolkit are malaria lymphatic filariasis dengue leishmaniasis onchocerciasis human African trypanosomiasis and schistosomiasis. It also includes information on other viral diseases (Rift Valley fever West Nile fever Chikungunya yellow fever) and trachoma. If other vector-borne diseases appear in a country or area vector control with an IVM approach should be adopted as per national priorities. Malaria as one of the most important vector-borne diseases in sub-Saharan Africa is the main focus of this document. Programmes targeting other vector-borne diseases can learn from the experiences gained from malaria vector control and presented here.
Author: Xavier Bonnefoy Publisher: World Health Organization ISBN: 9289071885 Category : Medical Languages : en Pages : 293
Book Description
The second half of the 20th century and the beginning of the 21st century witnessed important changes in ecology, climate and human behaviour that favoured the development of urban pests. Most alarmingly, urban planners now face the dramatic expansion of urban sprawl, in which city suburbs are growing into the natural habitats of ticks, rodents and other pests. Also, many city managers now erroneously assume that pest-borne diseases are relics of the past. All these changes make timely a new analysis of the direct and indirect effects of present-day urban pests on health. Such an analysis should lead to the development of strategies to manage them and reduce the risk of exposure. To this end, WHO invited international experts in various fields - pests, pest-related diseases and pest management - to provide evidence on which to base policies. These experts identified the public health risk posed by various pests and appropriate measures to prevent and control them. This book presents their conclusions and formulates policy options for all levels of decision-making to manage pests and pest-related diseases in the future. [Ed.]
Author: Michael S. Majewski Publisher: CRC Press ISBN: 9781439822609 Category : Nature Languages : en Pages : 240
Book Description
Most people know about the presence and health effects of pesticide residues in the water they drink. However, they may not realize the impact of atmospheric transportation and deposition of pesticides on water quality. Scientific studies of pesticides in various atmospheric matrices (air, rain, snow, aerosols, and fog) provide some of the answers.
Author: United States. Environmental Protection Agency. Office of Water Programs Publisher: ISBN: Category : Aquatic animals Languages : en Pages : 198
Author: World Health Organization
Author: World Health Organization
Author: World Health Organization
Author: 
Author: Institute of Medicine
Author: Farhat Afrin
Author: World Health Organization
Author: 
Author: Xavier Bonnefoy
Author: Michael S. Majewski
Author: United States. Environmental Protection Agency. Office of Water Programs