Genetics and Genomics of Neurobehavioral Disorders PDF Download

Author: Gene S. Fisch
Publisher: Springer Science & Business Media
ISBN: 1592593534
Category : Medical
Languages : en
Pages : 428

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Book Description
A clear and comprehensive account of how genetic abnormalities, neurobiology, and neuropsychology work together to manifest cognitive-behavioral dysfunction. The authors review the current status of research in autosomal disorders that produce cognitive-behavioral dysfunction and syndromal and nonsyndromal disorders that produce mental retardation.

Author: Gene S Fisch
Publisher:
ISBN: 9781468497632
Category :
Languages : en
Pages : 440

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Book Description

Author: Byron C. Jones
Publisher: CRC Press
ISBN: 1420003569
Category : Medical
Languages : en
Pages : 496

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Book Description
A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. International researchers incorporate several new developments in the field, including: De

Author: Moyra Smith
Publisher: World Scientific
ISBN: 9814759481
Category : Medical
Languages : en
Pages : 432

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Book Description
Unravelling Complexities in Genetics and Genomics: Impact on Diagnosis Counseling and Management reviews recent advances in defining genetic and genomic factors that play important roles in diseases in humans. It includes discussions on new technologies in DNA and RNA sequencing, genome analysis, and bioinformatics applied to the study of patients with specific disorders and to normal populations, and illustrates how modern molecular techniques can improve diagnoses and enable the design of specific targeted therapies and methods of prevention. Additional emphasis is placed on the genetic variants and genomic risk factors related to the development of complex common disorders, including neurobehavioral and neurocognitive disorders in children and adults and late onset disorders in adults, including atherosclerosis, type 2 diabetes, cancer, and neurodegenerative disorders. Physicians, nurses, genetic counselors, graduate students in genetics and genomics will find this book a valuable read. Contents:Expanding Insights into Genes and ExpressionGenomic Integrity and Relevance to DiseaseEpigenetics and EpigenomicsProteins, Proteomics, Protein Folding and ProteostasisGenotype–Phenotype Correlations and ComplexitiesImmune SystemLipids, Atherosclerosis, Metabolic Syndromes and DiabetesEarly-Onset Neurocognitive and Neurobehavioral DisordersIntegrating Advances in Neurobiology and Genetics into PsychiatryNeurodegenerative DiseasesCancerEpilogue Readership: Physicians, nurses, genetic counselors, graduate students in genetics and genomics.

Author: Alan F. Schatzberg
Publisher: American Psychiatric Pub
ISBN: 1585623091
Category : Medical
Languages : en
Pages : 933

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Book Description
Now updated to keep professionals current with the latest research and trends in the field, this edition covers both basic science and clinical practice, and draws on the talents of 53 new contributors to guarantee fresh, authoritative perspectives on advances in psychiatric drug therapy.

Author: Valter Tucci
Publisher: John Wiley & Sons
ISBN: 1118540719
Category : Medical
Languages : en
Pages : 648

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Book Description
The Handbook of Behavioral Genetics and Phenotyping represents an integrative approach to neurobehavioural genetics; worldwide experts in their field will review all chapters. Advanced overviews of neurobehavioural characteristics will add immense value to the investigation of animal mutants and provide unique information about the genetics and behavioural understanding of animal models, under both normal and pathological conditions. Cross-species comparisons of neurobehavioural phenotypes will pave the way for an evolutionary understanding of behaviour. Moreover, while biological sciences are progressing towards a holistic approach to investigate the complexity of organisms (i.e., “systems biology” approach), an integrated analysis of behavioural phenotyping is still lacking. The Handbook of Behavioral Genetics and Phenotyping strengthens the cross-talk within disciplines that investigate the fundamental basis of behaviour and genetics. This will be the first volume in which traditionally distant fields including genomics, behaviour, electrophysiology, neuroeconomics, and computational neuroscience, among others, are evaluated together and simultaneously accounted for during discussions of future perspectives.

Author: Peter Harper
Publisher: CRC Press
ISBN: 1444128590
Category : Medical
Languages : en
Pages : 417

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Book Description
Easy to use, and useful when kept close at hand in the room where you work. The book is a pleasure to read: the style elegant and authoritative.' Lancet'...this book is a wonderful reference to enable primary physicians to be informed about their patients.' Annals of Internal MedicineUniversally used across the world by genetic counsellors, medical

Author: Daniel Laskowitz
Publisher: CRC Press
ISBN: 1498766579
Category : Medical
Languages : en
Pages : 412

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Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Author: Sam Goldstein
Publisher: Guilford Press
ISBN: 1593852061
Category : Psychology
Languages : en
Pages : 509

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Book Description
While neurodevelopmental and genetic disorders are often diagnosed in childhood, understanding and managing the impact of these conditions is a lifelong challenge. This authoritative handbook presents cutting-edge knowledge to guide effective assessment and treatment throughout the adult years. Illuminated are the neurobiological bases and clinical characteristics of a broad range of conditions that affect learning and behavior as well as physical functioning and health. Following a consistent format, chapters comprehensively describe the developmental course of each disorder, the changing needs of adults, and ways to help them harness their strengths.

Author: Robert T. Gerlai
Publisher: Academic Press
ISBN: 0128041161
Category : Mathematics
Languages : en
Pages : 710

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Book Description
Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts