Mobile Genetic Elements PDF Download

Author: Wolfgang J. Miller
Publisher: Springer Science & Business Media
ISBN: 1592597556
Category : Medical
Languages : en
Pages : 295

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Book Description
Leading experts describe in step-by-step detail their most productive transposon-based methods and strategies for studying genome structure, function, and evolution. These readily reproducible techniques cover a wide range, including mutagenesis, transgenesis, gene silencing, and molecular systematics. Among the highlights are a series of DNA hybridization methods for analyzing the distribution and dynamics of mobile DNA at the hosts' genomic level, techniques for studying LTR retrotransposons in heterologous host systems, and mutagenesis protocols for investigating gene functions in a broad range of organisms. These cutting-edge methods offer investigators powerful genetic tools for dissecting the function of a specific gene, elaborating on the mechanisms leading to genetic change and diversity, and studying the evolutionary impact of mobile DNA on the biology and evolution of organisms.

Author: Michael Chandler
Publisher: John Wiley & Sons
ISBN: 1555819214
Category : Science
Languages : en
Pages : 1321

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Book Description
An exploration of the raw power of genetic material to refashion itself to any purpose... Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability. Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible presents a detailed account of the many different recombination systems that can rearrange genomes examines the tremendous impact of mobile DNA in virtually all organisms Mobile DNA III is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms. Mobile DNA III provides the most lucid reviews of these complex topics available anywhere.

Author: Paul J. Brindley
Publisher: CRC Press
ISBN: 1498712886
Category : Science
Languages : en
Pages : 138

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Book Description
Substantial proportions of the genome of most eukaryotes, including those of metazoan parasites, are comprised of repetitive sequences. Mobile genetic elements (MGEs) constitute much of the repetitive component, particularly the interspersed sequences. This volume of nine chapters addresses MGEs that have colonized the genomes of medically importan

Author: James Alan Shapiro
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 714

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Book Description
Mobile Genetic Elements introduces the nonspecialist to the biology and genetics of mobile elements. It attempts to make the biochemistry of DNA rearrangements more accessible to embryologists and evolutionists, and to illuminate the related developmental cycles to the biochemist. The book also shows how natural the activity of mobile elements can be in diverse biological situations. The chapters describe several well-studied cases in which genetic determinants-often identified as specific nucleic acid sequences-repeatedly change their positions within or between cellular genomes. Because thei ...

Author: David J. Sherratt
Publisher: Oxford University Press, USA
ISBN:
Category : Art
Languages : en
Pages : 208

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Book Description
Mobile genetic elements are present in all organisms. They are a major cause of spontaneous genetic change and are now exploited by geneticists as important tools for obtaining mutants, isolating genes, and for studying gene expression. The approach is comparative and the book addresses transposable elements as genetic tools, mechanisms that lead to genetic change, and how novel elements contribute to organism biology and evolution.

Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0

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Book Description

Author: Austin BURT
Publisher: Harvard University Press
ISBN: 0674029119
Category : Science
Languages : en
Pages : 613

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Book Description
Covering all species from yeast to humans, this is the first book to tell the story of selfish genetic elements that act narrowly to advance their own replication at the expense of the larger organism.

Author: Adam P. Roberts
Publisher: CRC Press
ISBN: 1000724700
Category : Science
Languages : en
Pages : 456

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Book Description
As our understanding of mobile genetic elements continues to grow we are gaining a deeper appreciation of their importance in shaping the bacterial genome and in the properties they confer to their bacterial hosts. These include, but are by no means limited to, resistance to antibiotics, and heavy metals, toxin production and increased virulence, production of antibiotics and the ability to utilize a diverse range of metabolic substrates. We are also gaining an understanding of diversity of these elements and their interactions with each other; a property which continually complicates any attempt to classify them. We are learning more about the molecular mechanisms by which they translocate to new genomic sites both within genomes and between different bacteria. This book provides a timely, state of the art update on the properties of an important selection of different bacterial integrative mobile genetic elements and the myriad of different ways in which they move and influence the biology of the host bacterium. The chapters are all written by authors who have undertaken pioneering work in their respective fields, making this book vital reading for all who are interested in the biology of bacteria and the mobile elements they carry.

Author: Douglas E. Berg
Publisher: Amer Society for Microbiology
ISBN: 9781555810054
Category : Medical
Languages : en
Pages : 972

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Book Description
Documents the remarkable mobility of DNA in procaryotic and eucaryotic genomes: the ability of various DNA segments to move to new sites, to invert, and to undergo deletion or amplification, generally without the extensive DNA sequence homology needed for classical recombination. Seventy contributors explore the mechanisms of these rearrangements, how they are regulated, their biological consequences, and their potential use as research tools. For students and researchers of molecular genetics. Annotation copyrighted by Book News, Inc., Portland, OR

Author: Hiromi Nishida
Publisher: Springer
ISBN: 9811334110
Category : Science
Languages : en
Pages : 278

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Book Description
This book comprehensively discusses our current understanding of the role and biological mechanisms of horizontal transfer of genetic elements in the environment, which has been important in the evolution of prokaryotes (archaea and bacteria). Horizontal transfer of genetic elements generates variations of prokaryotes and their genomes. Comparative studies of genomes revealed that it frequently occurred during archaeal and bacterial evolution. The book introduces a variety of studies related to horizontal gene transfer, gene silencing, plasmids, phages, transposons, and the emergence of microbes that degrade man-made xenobiotics and have antimicrobial resistance. Written by leading researchers in DNA traffic, the book is a valuable guide to horizontal transfer for both young scientists and experts in the field.