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Mobilizing Mutations

Mobilizing Mutations PDF Author: Daniel Navon
Publisher: University of Chicago Press
ISBN: 022663809X
Category : Medical
Languages : en
Pages : 409

Book Description
With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.

Mobilizing Mutations

Mobilizing Mutations PDF Author: Daniel Navon
Publisher: University of Chicago Press
ISBN: 022663809X
Category : Medical
Languages : en
Pages : 409

Book Description
With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.

All God's Mistakes

All God's Mistakes PDF Author: Charles L. Bosk
Publisher: University of Chicago Press
ISBN: 9780226066820
Category : Health & Fitness
Languages : en
Pages : 228

Book Description
In one case after another, Charles L. Bosk reveals the process by which parents, physicians and other health professionals come to guide decisions about pregnancies. A story of both extraordinary drama and ordinary routine, this is a pioneering case study of authority and control in a pediatric hospital, showing how genetic counselors work with colleagues and with parents to be, and how they deal with their powerlessness to control life-and-death decisions that they must address.

Mobilizing Others

Mobilizing Others PDF Author: Carmen Taleghani-Nikazm
Publisher: John Benjamins Publishing Company
ISBN: 902726158X
Category : Language Arts & Disciplines
Languages : en
Pages : 293

Book Description
Requesting, recruitment, and other ways of mobilizing others to act have garnered much interest in Conversation Analysis and Interactional Linguistics. This volume takes a holistic perspective on the practices that we use to get others to act either with us, or for us. It argues for a more explicit focus on ‘activity’ in unpacking the linguistic and embodied choices we make in designing mobilizing moves. Drawing on studies from a variety of different languages and settings, the collected studies in this volume illustrate how interactants design their turns not only for specific recipients, but also for a specific interactional situation. In doing so, speakers are able to mobilize others’ cooperation, contribution, or assistance in the most appropriate and economical ways. By focusing on ‘situation design’ across languages and settings, this volume provides new insights into the ways in which the ongoing activity, with its attendant participation structures, shapes the design, placement, and understanding of moves which mobilize others to act.

The Immigrant Rights Movement

The Immigrant Rights Movement PDF Author: Walter J. Nicholls
Publisher: Stanford University Press
ISBN: 1503609332
Category : Social Science
Languages : en
Pages : 428

Book Description
In the months leading up to the 2016 presidential election, liberal outcry over ethnonationalist views promoted a vision of America as a nation of immigrants. Given the pervasiveness of this rhetoric, it can be easy to overlook the fact that the immigrant rights movement began in the US relatively recently. This book tells the story of its grassroots origins, through its meteoric rise to the national stage. Starting in the 1990s, the immigrant rights movement slowly cohered over the demand for comprehensive federal reform of immigration policy. Activists called for a new framework of citizenship, arguing that immigrants deserved legal status based on their strong affiliation with American values. During the Obama administration, leaders were granted unprecedented political access and millions of dollars in support. The national spotlight, however, came with unforeseen pressures—growing inequalities between factions and restrictions on challenging mainstream views. Such tradeoffs eventually shattered the united front. The Immigrant Rights Movement tells the story of a vibrant movement to change the meaning of national citizenship, that ultimately became enmeshed in the system that it sought to transform.

Disease Control Priorities, Third Edition (Volume 6)

Disease Control Priorities, Third Edition (Volume 6) PDF Author: King K. Holmes
Publisher: World Bank Publications
ISBN: 1464805253
Category : Medical
Languages : en
Pages : 506

Book Description
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

The Politics of Pain Medicine

The Politics of Pain Medicine PDF Author: S. Scott Graham
Publisher: University of Chicago Press
ISBN: 022626405X
Category : Language Arts & Disciplines
Languages : en
Pages : 253

Book Description
Exploring the medical rhetoric surrounding pain medicine, the author chronicles the work of interdisciplinary pain management specialists to found a new science of pain and a new approach to pain medicine grounded in a more comprehensive biospychosocial model. His analysis shows how these materials shape the healthcare community's understanding of what pain medicine is, how the medicine should be practiced and regulated, and how practitioner-patient relationships are best managed.

After the Internet

After the Internet PDF Author: Tiziana Terranova
Publisher: MIT Press
ISBN: 1635901685
Category : Social Science
Languages : en
Pages : 217

Book Description
On the internet's transformation from communication tool to computational infrastructure. The internet is no more. If it still exists, it does so only as a residual technology, still effective in the present but less intelligible as such. After nearly two decades and a couple of financial crises, it has become the almost imperceptible background of today’s Corporate Platform Complex (CPC)—a pervasive planetary technological infrastructure that meshes communication with computation. In the essays collected in this book, written mostly between the mid-2000s and the late 2010s, Tiziana Terranova bears witness to this monstrous transformation. Mobilizing theories of cognitive capitalism, neo-monadology, and sympathetic cooperation, considering ideas such as the attention economy and its psychopathologies, and evoking the relation between algorithmic automation and the Common, she provides real-time takes on the mutations that have changed the technological, cultural, and economic ethos of the Internet. Mostly conceived, elaborated, and discussed in collective activist spaces, After the Internet is neither apocalyptic lamentation nor melancholic “rise and fall” story of betrayed great expectations. On the contrary, it looks within the folds of the recent past to unfold the potential futurities that the post-digital computational present still entails.

The Mobilization of Shame

The Mobilization of Shame PDF Author: Robert F. Drinan
Publisher: Yale University Press
ISBN: 9780300093193
Category : Political Science
Languages : en
Pages : 260

Book Description
13 The Right to Food

Genetic Analysis of Complex Disease

Genetic Analysis of Complex Disease PDF Author: William K. Scott
Publisher: John Wiley & Sons
ISBN: 1119104076
Category : Science
Languages : en
Pages : 340

Book Description
Genetic Analysis of Complex Diseases An up-to-date and complete treatment of the strategies, designs and analysis methods for studying complex genetic disease in human beings In the newly revised Third Edition of Genetic Analysis of Complex Diseases, a team of distinguished geneticists delivers a comprehensive introduction to the most relevant strategies, designs and methods of analysis for the study of complex genetic disease in humans. The book focuses on concepts and designs, thereby offering readers a broad understanding of common problems and solutions in the field based on successful applications in the design and execution of genetic studies. This edited volume contains contributions from some of the leading voices in the area and presents new chapters on high-throughput genomic sequencing, copy-number variant analysis and epigenetic studies. Providing clear and easily referenced overviews of the considerations involved in genetic analysis of complex human genetic disease, including sampling, design, data collection, linkage and association studies and social, legal and ethical issues. Genetic Analysis of Complex Diseases also provides: A thorough introduction to study design for the identification of genes in complex traits Comprehensive explorations of basic concepts in genetics, disease phenotype definition and the determination of the genetic components of disease Practical discussions of modern bioinformatics tools for analysis of genetic data Reflecting on responsible conduct of research in genetic studies, as well as linkage analysis and data management New expanded chapter on complex genetic interactions This latest edition of Genetic Analysis of Complex Diseases is a must-read resource for molecular biologists, human geneticists, genetic epidemiologists and pharmaceutical researchers. It is also invaluable for graduate students taking courses in statistical genetics or genetic epidemiology.

Human Geopolitics

Human Geopolitics PDF Author: Alan Gamlen
Publisher: Oxford University Press
ISBN: 0192569988
Category : Political Science
Languages : en
Pages : 304

Book Description
Human geopolitics, the competition for population rather than territory, is an essential but weakly understood dimension of world politics today. Such competition has preceded violent conflict throughout history, but has been muted since the Treaties of Westphalia laid the territorial foundations of the modern international system in the mid-seventeenth century. Today, however, human geopolitics is being resurrected in unanticipated ways, as governments are enabled and encouraged to engage their emigrant diasporas. How and why is this happening? Until now these questions have been difficult to answer. The majority of research attention has focused on questions of immigration policy in a handful of wealthy migrant destination countries, largely ignoring the emigration policies that preoccupy the worlds many migrant origin states. This book addresses that research imbalance, by focusing on the overlooked sending side of migration policy. Drawing on data covering all UN members across the post-WWII period, and fieldwork with high-level policy makers across 60 states and a dozen international organisations, the book charts the re-emergence of human geopolitics through the global spread of diaspora institutions government ministries and offices dedicated to emigrants and their descendants. It calls for the development of stronger guiding principles and evaluation frameworks to govern these new state-diaspora relations in an era of unprecedented global interdependence.