Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics PDF Download

Author: Gorachand Dutta
Publisher: Springer Nature
ISBN: 9811971307
Category : Science
Languages : en
Pages : 252

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Book Description
This book reviews the potential of next-generation point-of-care diagnosis in healthcare. It also discusses the printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection. The book presents the development of sensory systems based on the use of nanomaterials. It examines different biosensors for medical diagnosis using surface modification strategies of transducers. It presents electrochemical concepts based on different nanobiomaterials and nanocomposites for cancer theranostics. Notably, the book examines the recent advances in wearable, cost-effective hemodynamic sensors to detect diseases at an early stage. It further explores the combination of redox cycling and electrochemical detection to develop ultrasensitive and reproducible biosensors for point-of-care testing. Finally, the book summarizes the significant challenges in the point of care diagnostics and its future opportunities in healthcare. ​

Author: Manashjit Gogoi
Publisher: Springer Nature
ISBN: 9811951411
Category : Medical
Languages : en
Pages : 287

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Book Description
This book examines the role of nanobiosensors in point-of-care applications for personalized healthcare and management. It begins by discussing various biomaterials that are used for the development of biosensors in medical diagnostics, and reviews advances in their fabrication and the miniaturization of biosensor devices for lab-on-chip analysis. In turn, it explores the rapidly evolving applications of nanomaterials in the context of biomaterial diagnostics. The book also explores the immense potential of biosensors in medical diagnostics, where they are increasingly being used to detect a wide range of biomolecules and biomarkers. In closing, it discusses the current challenges and outlines the future role of nanobiosensors in the development of next-generation point-of-care applications.

Author: Pranjal Chandra
Publisher: Springer
ISBN: 981104726X
Category : Medical
Languages : en
Pages : 396

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Book Description
This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.

Author: Pankaj Suman
Publisher: Springer Nature
ISBN: 981155823X
Category : Medical
Languages : en
Pages : 245

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Book Description
This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.

Author: Pranjal Chandra
Publisher: IET
ISBN: 1849199507
Category : Medical
Languages : en
Pages : 637

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Book Description
The critical goal of nanobiosensors is to detect any biochemical and/or biophysical signal related to a specific disease at the level of a single or few molecules. Nanobiosensors have been successful for in vitro as well as in vivo detection of several biomolecules. It is expected that this technology will revolutionize point-of-care and personalized diagnostics, and will be extremely applicable for early disease detection. This book starts with a brief introduction of the biosensors and then focuses mainly on the emerging nanobiosensor technologies which are geared towards onsite clinical applications and those which can be used as a personalized diagnostic device. Written by an international team of researchers who are actively developing these technologies, Nanobiosensors for Personalized and Onsite Biomedical Diagnosis covers the latest advances in the field of biosensors and biosensing applications. This important book includes an assessment of some current and emerging technologies for detecting protein biomarkers and other potential cancer biomarkers and is essential reading for researchers and graduate students in the field. Medics including radiologists and clinicians will also find it invaluable.

Author: Sabu Thomas
Publisher: Elsevier
ISBN: 0128236523
Category : Technology & Engineering
Languages : en
Pages : 634

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Book Description
Nanosensors for Smart Manufacturing provides information on the fundamental design concepts and emerging applications of nanosensors in smart manufacturing processes. In smart production, if the products and machines are integrated, embedded, or equipped with sensors, the system can immediately collect the current operating parameters, predict the product quality, and then feed back the optimal parameters to machines in the production line. In this regard, smart sensors and their wireless networks are important components of smart manufacturing. Nanomaterials-based sensors (nanosensors) offer several advantages over their microscale counterparts, including lower power consumption, fast response time, high sensitivity, lower concentration of analytes, and smaller interaction distance between sensors and products. With the support of artificial intelligence (AI) tools such as fuzzy logic, genetic algorithms, neural networks, and ambient intelligence, sensor systems have become smarter. This is an important reference source for materials scientists and engineers who want to learn more about how nanoscale sensors can enhance smart manufacturing techniques and processes. Outlines the smart nanosensor classes used in manufacturing applications Shows how nanosensors are being used to make more efficient manufacturing systems Assesses the major obstacles to designing nanosensor-based manufacturing systems at an industrial scale

Author: Prashant M. Pawar
Publisher: Springer
ISBN: 3319535560
Category : Technology & Engineering
Languages : en
Pages : 1150

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Book Description
This volume originates from the proceedings of a multidisciplinary conference, Techno-Societal 2016 in Maharashtra, India, that brings together faculty members of various engineering colleges to solve Indian regional relevant problems under the guidance of eminent researchers from various reputed organizations. The focus is on technologies that help develop and improve society, in particular on issues such as the betterment of differently abled people, environment impact, livelihood, rural employment, agriculture, healthcare, energy, transport, sanitation, water, education. This conference aims to help innovators to share their best practices or products developed to solve specific local problems which in turn may help the other researchers to take inspiration to solve problems in their region. On the other hand, technologies proposed by expert researchers may find applications in different regions. This back and forth process for local-global interaction will help in solving local problems by global approach and help in solving global problems by improving local conditions.

Author: Spiridon E. Kintzios
Publisher:
ISBN: 9781523112265
Category : Biosensors
Languages : en
Pages : 355

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Book Description
This book describes the principles, design and applications of a new generation of analytical and diagnostic biomedical devices, characterized by their very small size, ease of use, multi-analytical capabilities and speed to provide handheld and mobile point-of-care (POC) diagnostics.

Author: Roger J Narayan
Publisher: Woodhead Publishing
ISBN: 0081000782
Category : Medical
Languages : en
Pages : 316

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Book Description
Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring. Provides essential knowledge for designers and manufacturers of biosensors for point-of-care applications Provides comprehensive coverage of the fundamentals, materials, technologies, and applications of medical biosensors for point-of-care applications Includes contributions from leading international researchers with extensive experience in developing medical biosensors Discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care

Author: Pradipta Ranjan Rauta
Publisher: CRC Press
ISBN: 0429535015
Category : Medical
Languages : en
Pages : 410

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Book Description
Nanotechnology in biology and medicine: Research advancements & future perspectives is focused to provide an interdisciplinary, integrative overview on the developments made in nanotechnology till date along with the ongoing trends and the future prospects. It presents the basics, fundamental results/current applications and latest achievements on nanobiotechnological researches worldwide scientific era. One of the major goals of this book is to highlight the multifaceted issues on or surrounding of nanotechnology on the basis of case studies, academic and theoretical articles, technology transfer (patents and copyrights), innovation, economics and policy management. Moreover, a large variety of nanobio-analytical methods are presented as a core asset to the early career researchers. This book has been designed for scientists, academician, students and entrepreneurs engaged in nanotechnology research and development. Nonetheless, it should be of interest to a variety of scientific disciplines including agriculture, medicine, drug and food material sciences and consumer products. Features It provides a thoroughly comprehensive overview of all major aspects of nanobiotechnology, considering the technology, applications, and socio-economic context It integrates physics, biology, and chemistry of nanosystems It reflects the state-of-the-art in nanotechnological research (biomedical, food, agriculture) It presents the application of nanotechnology in biomedical field including diagnostics and therapeutics (drug discovery, screening and delivery) It also discusses research involving gene therapy, cancer nanotheranostics, nano sensors, lab-on-a-chip techniques, etc. It provides the information about health risks of nanotechnology and potential remedies. It offers a timely forum for peer-reviewed research with extensive references within each chapter