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Pain, Touch, and Decision Making

Pain, Touch, and Decision Making PDF Author: Lina Koppel
Publisher: Linköping University Electronic Press
ISBN: 9179297862
Category : Electronic books
Languages : en
Pages : 87

Book Description
Stimulation of sensory nerves can give rise to powerful affective experiences. Noxious stimuli can give rise to pain, an unpleasant experience which, in turn, causes suffering and constitutes a major societal burden. Touch, on the other hand, can feel pleasant and plays an important role in social relationships and well-being. Slow, gentle stroking of the skin in particular has been shown to activate C-tactile (CT) afferents, which are thought to signal affective and socially relevant aspects of touch. However, little is known about how pain and affective touch influence everyday decision making. In Paper I, we investigated the effect of acute physical pain on risk taking and intertemporal choice. Participants (n = 109) performed a series of economic decision-making tasks, once while experiencing acute thermal pain and once in a no-pain control condition. Results indicated that pain increased risk taking for monetary gains but not for equivalent losses, and increased impatience. In Paper II, we investigated the effect of affective touch on betrayal aversion, altruism, and risk taking. Participants (n = 120) performed a series of economic decision-making tasks, once while being stroked on the forearm at CT-optimal speed using a soft painter’s brush and once in a no-touch control condition. Results indicated no effect of affective touch on any of the outcome measures. In Paper III, we investigated how the ability to affect an upcoming painful event via voluntary action influences cortical processing of ongoing somatosensory stimulation. fMRI data was collected from 30 participants while they performed a task that involved pressing a response button to reduce the duration of upcoming thermal stimuli. Whole-brain analyses revealed no significant task-related effects in brain regions typically involved in pain, except activation in a cluster in anterior cingulate cortex (ACC) was greater when upcoming stimulation was painful than when it was nonpainful. However, region-of-interest analyses in anterior insula (AI) and midcingulate cortex (MCC) indicated that the noxious nature of the upcoming stimulation, as well as the ability to affect it, influenced processing of ongoing stimulation in both of these regions. Activation in MCC, but not AI, also correlated with response times. Taken together, these studies contribute to the broader understanding of everyday decision making, and of how affective experiences such as pain and touch shape everyday decisions and behaviors. Stimulering av nervfibrer i huden kan ge upphov till starka känsloupplevelser. Skadliga eller potentiellt skadliga stimuli kan ge upphov till smärta, en obehaglig upplevelse som i sin tur orsakar lidande och har stora socioekonomiska konsekvenser. Beröring, å andra sidan, kan upplevas som behagligt och är en viktig del av sociala relationer. Förhållandevis lite kunskap finns dock om hur smärta och beröring påverkar vardagligt beslutsfattande. Blir vi otåliga av att uppleva smärta? Tar vi fler risker? Gör beröring oss snällare och mer tillitsfulla? I denna avhandling presenteras tre studier som försöker svara på denna typ av frågor. I den första studien fick deltagarna smärtsam värmestimulering samtidigt som de fattade beslut om pengar. Besluten involverade t.ex. att välja mellan en säker vinst på 50 kr eller att singla slant om att vinna 100 kr. Resultaten visade att smärta ökade risktagande för vinster, men inte för motsvarande förluster. Deltagare som upplevde smärta var även mer otåliga, dvs. de föredrog i större utsträckning snabba belöningar. I den andra studien fick deltagarna beröring med en mjuk pensel samtidigt som de fattade beslut. Lätt, smekande beröring aktiverar en särskild typ av nervfibrer, som tros signalera affektiva och socialt relevanta aspekter av beröring. Beröring ökar även utsöndringen av hormonet oxytocin, som sägs öka känslan av tillit till andra människor, även om de vetenskapliga bevisen för detta är motstridiga. Resultaten av studien visade ingen effekt av beröring på beslutsfattande. I den tredje studien undersöktes hjärnans aktivitet vid smärtsam stimulering. Vi vet sedan tidigare att hjärnan inte bara reagerar på det som händer just nu, utan att den även förbereder inför vad som kan komma att hända i framtiden. Deltagarna fick smärtsam eller icke-smärtsam värmestimulering samtidigt som de utförde en uppgift som innebar att de skulle trycka på en knapp för att förkorta en kommande värmestimulering. Resultaten visade att hjärnans bearbetning av pågående stimulering påverkades av huruvida nästkommande stimulering var smärtsam eller inte och huruvida den gick att påverka. Sammantaget bidrar dessa studier till en ökad förståelse av hur människor fattar beslut och hur upplevelser som smärta och beröring påverkar vardagligt beslutfattande och beteende. Smärta har en stark koppling till beteende, eftersom vi snabbt måste kunna agera för att undvika skada. Beröring, däremot, upplevs på olika sätt beroende på den sociala kontexten, vilket troligtvis också påverkar beröringens effekt på beteende.

Pain, Touch, and Decision Making

Pain, Touch, and Decision Making PDF Author: Lina Koppel
Publisher: Linköping University Electronic Press
ISBN: 9179297862
Category : Electronic books
Languages : en
Pages : 87

Book Description
Stimulation of sensory nerves can give rise to powerful affective experiences. Noxious stimuli can give rise to pain, an unpleasant experience which, in turn, causes suffering and constitutes a major societal burden. Touch, on the other hand, can feel pleasant and plays an important role in social relationships and well-being. Slow, gentle stroking of the skin in particular has been shown to activate C-tactile (CT) afferents, which are thought to signal affective and socially relevant aspects of touch. However, little is known about how pain and affective touch influence everyday decision making. In Paper I, we investigated the effect of acute physical pain on risk taking and intertemporal choice. Participants (n = 109) performed a series of economic decision-making tasks, once while experiencing acute thermal pain and once in a no-pain control condition. Results indicated that pain increased risk taking for monetary gains but not for equivalent losses, and increased impatience. In Paper II, we investigated the effect of affective touch on betrayal aversion, altruism, and risk taking. Participants (n = 120) performed a series of economic decision-making tasks, once while being stroked on the forearm at CT-optimal speed using a soft painter’s brush and once in a no-touch control condition. Results indicated no effect of affective touch on any of the outcome measures. In Paper III, we investigated how the ability to affect an upcoming painful event via voluntary action influences cortical processing of ongoing somatosensory stimulation. fMRI data was collected from 30 participants while they performed a task that involved pressing a response button to reduce the duration of upcoming thermal stimuli. Whole-brain analyses revealed no significant task-related effects in brain regions typically involved in pain, except activation in a cluster in anterior cingulate cortex (ACC) was greater when upcoming stimulation was painful than when it was nonpainful. However, region-of-interest analyses in anterior insula (AI) and midcingulate cortex (MCC) indicated that the noxious nature of the upcoming stimulation, as well as the ability to affect it, influenced processing of ongoing stimulation in both of these regions. Activation in MCC, but not AI, also correlated with response times. Taken together, these studies contribute to the broader understanding of everyday decision making, and of how affective experiences such as pain and touch shape everyday decisions and behaviors. Stimulering av nervfibrer i huden kan ge upphov till starka känsloupplevelser. Skadliga eller potentiellt skadliga stimuli kan ge upphov till smärta, en obehaglig upplevelse som i sin tur orsakar lidande och har stora socioekonomiska konsekvenser. Beröring, å andra sidan, kan upplevas som behagligt och är en viktig del av sociala relationer. Förhållandevis lite kunskap finns dock om hur smärta och beröring påverkar vardagligt beslutsfattande. Blir vi otåliga av att uppleva smärta? Tar vi fler risker? Gör beröring oss snällare och mer tillitsfulla? I denna avhandling presenteras tre studier som försöker svara på denna typ av frågor. I den första studien fick deltagarna smärtsam värmestimulering samtidigt som de fattade beslut om pengar. Besluten involverade t.ex. att välja mellan en säker vinst på 50 kr eller att singla slant om att vinna 100 kr. Resultaten visade att smärta ökade risktagande för vinster, men inte för motsvarande förluster. Deltagare som upplevde smärta var även mer otåliga, dvs. de föredrog i större utsträckning snabba belöningar. I den andra studien fick deltagarna beröring med en mjuk pensel samtidigt som de fattade beslut. Lätt, smekande beröring aktiverar en särskild typ av nervfibrer, som tros signalera affektiva och socialt relevanta aspekter av beröring. Beröring ökar även utsöndringen av hormonet oxytocin, som sägs öka känslan av tillit till andra människor, även om de vetenskapliga bevisen för detta är motstridiga. Resultaten av studien visade ingen effekt av beröring på beslutsfattande. I den tredje studien undersöktes hjärnans aktivitet vid smärtsam stimulering. Vi vet sedan tidigare att hjärnan inte bara reagerar på det som händer just nu, utan att den även förbereder inför vad som kan komma att hända i framtiden. Deltagarna fick smärtsam eller icke-smärtsam värmestimulering samtidigt som de utförde en uppgift som innebar att de skulle trycka på en knapp för att förkorta en kommande värmestimulering. Resultaten visade att hjärnans bearbetning av pågående stimulering påverkades av huruvida nästkommande stimulering var smärtsam eller inte och huruvida den gick att påverka. Sammantaget bidrar dessa studier till en ökad förståelse av hur människor fattar beslut och hur upplevelser som smärta och beröring påverkar vardagligt beslutfattande och beteende. Smärta har en stark koppling till beteende, eftersom vi snabbt måste kunna agera för att undvika skada. Beröring, däremot, upplevs på olika sätt beroende på den sociala kontexten, vilket troligtvis också påverkar beröringens effekt på beteende.

Neuroscience of Decision Making

Neuroscience of Decision Making PDF Author: Oshin Vartanian
Publisher: Psychology Press
ISBN: 113685987X
Category : Psychology
Languages : en
Pages : 369

Book Description
The intersection between the fields of behavioral decision research and neuroscience has proved to be fertile ground for interdisciplinary research. Whereas the former is rich in formalized models of choice, the latter is rife with techniques for testing behavioral models at the brain level. As a result, there has been the rapid emergence of progressively more sophisticated biological models of choice, geared toward the development of ever more complete mechanistic models of behavior. This volume provides a coherent framework for distilling some of the key themes that have emerged as a function of this research program, and highlights what we have learned about judgment and decision making as a result. Although topics that are theoretically relevant to judgment and decision making researchers are addressed, the book also ventures somewhat beyond the traditional boundaries of this area to tackle themes that would of interest to a greater community of scholars. Neuroscience of Decision Making provides contemporary and essential reading for researchers and students of cognitive psychology, neuroscience, philosophy, and economics.

Nanobrain

Nanobrain PDF Author: Anirban Bandyopadhyay
Publisher: CRC Press
ISBN: 1439875510
Category : Computers
Languages : en
Pages : 372

Book Description
Making an artificial brain is not a part of artificial intelligence. It will be a revolutionary journey of mankind exploring a science where one cannot write an equation, a material will vibrate like geometric shape, and then those shapes will change to make decisions. Geometry of silence plays like a musical instrument to mimic a human brain; our thoughts, imagination, everything would be a 3D shape playing as music; composing music would be the brain’s singular job. For a century, the Turing machine ruled human civilization; it was believed that irrespective of complexity all events add up linearly. This book is a thesis to explore the science of decision-making where events are 3D-geometric shapes, events grow within and above, never side by side. ​ The book documents inventions and discoveries in neuroscience, computer science, materials science, mathematics and chemistry that explore the possibility of brain or universe as a time crystal. The philosophy of Turing, the philosophy of membrane-based neuroscience and the philosophy of linear, sequential thought process are challenged here by considering that a nested time crystal encompasses the entire conscious universe. Instead of an algorithm, the pattern of maximum free will is generated mathematically and that very pattern is encoded in materials such that its natural vibration integrates random events exactly similar to the way nature does it in every remote corner of our universe. Find how an artificial brain avoids any necessity for algorithm or programming using the pattern of free will.

Ramamurthy's Decision Making in Pain Management

Ramamurthy's Decision Making in Pain Management PDF Author: Ameet Nagpal
Publisher: JP Medical Ltd
ISBN: 9386261456
Category : Medical
Languages : en
Pages : 459

Book Description
This new edition provides clinicians with the latest advances in the identification, diagnosis and management of acute and chronic pain conditions and syndromes. Beginning with an overview of pain evaluation, the next chapters explain acute and chronic pain. The following chapters examine different types of pain including cancer, thoracic, lower back, head and neck, and more. Each chapter has been fully revised and the third edition features many new topics, including a complete chapter dedicated to opioid pharmacology. Authored by recognised Texas-based experts in the field, the text is presented in a clear, algorithmic approach, enhanced by clinical photographs and figures. Key points Fully revised, third edition presenting latest advances in diagnosis and management pain Features many new topics including a chapter on opioid pharmacology Authored by recognised Texas-based experts in the field Previous edition (9780323019743) published in 2006

Brain Computations

Brain Computations PDF Author: Edmund T. Rolls
Publisher: Oxford University Press, USA
ISBN: 0198871104
Category : Medical
Languages : en
Pages : 954

Book Description
In order to understand how the brain works, it is essential to know WHAT is computed by different brain systems, and HOW those computations are performed. This is the aim of Brain Computations: What and How. Pioneering in its approach, this book will be of interest to all scientists interested in brain function and how the brain works

Decision Making in Medicine

Decision Making in Medicine PDF Author: Stuart B. Mushlin
Publisher: Elsevier Health Sciences
ISBN: 0323041078
Category : Medical
Languages : en
Pages : 754

Book Description
This popular reference facilitates diagnostic and therapeutic decision making for a wide range of common and often complex problems faced in outpatient and inpatient medicine. Comprehensive algorithmic decision trees guide you through more than 245 disorders organized by sign, symptom, problem, or laboratory abnormality. The brief text accompanying each algorithm explains the key steps of the decision making process, giving you the clear, clinical guidelines you need to successfully manage even your toughest cases. An algorithmic format makes it easy to apply the practical, decision-making approaches used by seasoned clinicians in daily practice. Comprehensive coverage of general and internal medicine helps you successfully diagnose and manage a full range of diseases and disorders related to women's health, emergency medicine, urology, behavioral medicine, pharmacology, and much more. A Table of Contents arranged by organ system helps you to quickly and easily zero in on the information you need. More than a dozen new topics focus on the key diseases and disorders encountered in daily practice. Fully updated decision trees guide you through the latest diagnostic and management guidelines.

Emotion and Decision Making Explained

Emotion and Decision Making Explained PDF Author: Edmund T. Rolls
Publisher: Oxford University Press
ISBN: 0199659893
Category : Business & Economics
Languages : en
Pages : 729

Book Description
What produces emotions? Why do we have emotions? How do we have emotions? Why do emotional states feel like something? What is the relation between emotion, and reward value, and subjective feelings of pleasure? These are just some of the question considered in this book, written by a leading neuroscientist in this field.

Affective Touch and the Neurophysiology of CT Afferents

Affective Touch and the Neurophysiology of CT Afferents PDF Author: Håkan Olausson
Publisher: Springer
ISBN: 1493964186
Category : Medical
Languages : en
Pages : 430

Book Description
CT afferents are receptors in mammalian hairy skin that fire action potentials when the skin is touched lightly which makes them particularly important in affective touch. Traditionally neuroscientific research has focused on more discriminative and haptic properties of touch that are mediated by large myelinated afferents and the coding properties and functional organization of unmyelinated CT afferents have been studied much less. The proposed volume will draw together existing knowledge in this nascent field. Separate sections will address (1) how we can measure affective touch, (2) CT structure and physiology, (3) CT processing, (4) the contribution of CTs to sexual behavior, (5) clinical relevance, (6) commercial relevance, and (7) future research considerations.​

Painful Choices

Painful Choices PDF Author: David A. Welch
Publisher: Princeton University Press
ISBN: 9780691123400
Category : Political Science
Languages : en
Pages : 296

Book Description
Japan's endless patience with diplomacy in its conflict with Russia over the Northern Territories; America's decision to commit large-scale military force to Vietnam vs. its ultimate decision to withdraw; and Canada's two abortive flirtations with free trade with the United States in 1911 and 1948 vs. its embrace of free trade in the late 1980s."--Jacket.

Supporting a Physiologic Approach to Pregnancy and Birth

Supporting a Physiologic Approach to Pregnancy and Birth PDF Author: Melissa D. Avery
Publisher: John Wiley & Sons
ISBN: 1118612000
Category : Medical
Languages : en
Pages : 287

Book Description
Supporting a Physiologic Approach to Pregnancy and Birth: A Practical Guide provides an overview of current evidence and a range of practical suggestions to promote physiologic birth within the United States healthcare system. Presenting the latest evidence available on practical approaches and minimal interventions, this book looks into clinic exam rooms and hospital labor units to investigate the possibilities for improving the pregnancy and labor experience. Contributors discuss recent research and other published information and present a range of ideas, tools, and solutions for maternity care clinicians, including midwives, nurses, physicians, and other members of the perinatal team. An invaluable resource, Supporting a Physiologic Approach to Pregnancy and Birth is a must-have practical guide for those involved in all aspects of pregnancy and birth.