Pharmacovigilance for Herbal and Traditional Medicines PDF Download

Author: Joanne Barnes
Publisher: Springer Nature
ISBN: 3031072758
Category : Science
Languages : en
Pages : 406

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Book Description
This remarkable new book is the first text dedicated to the topic of pharmacovigilance for herbal and traditional medicines. Taking a truly global perspective, this volume draws together contributions from a diverse group of experts, writing on current knowledge and practices in pharmacovigilance for herbal and traditional medicines, and on advances and innovation in monitoring the safety of this unique and complex category of products and preparations. In part one, the book discusses the current status of pharmacovigilance for herbal and traditional medicines, including the importance of natural products chemistry to harms, and its relevance in considering how pharmacovigilance for these products could be undertaken. Several other chapters discuss methodological approaches and ongoing challenges in pharmacovigilance for herbal and traditional medicines, including issues relating to nomenclature, coding and classification, and the nuances involved in causality assessment. Part two of the book focusses on pharmacovigilance for herbal and traditional medicines around the world, with chapters from authors in several different countries representing diverse historical, ethnic, cultural, social and political contexts. These chapters provide deeper insights and perspectives into spontaneous reporting for herbal and traditional medicines in those countries, and in the context of the local use, practice and regulatory landscape for these products. Part two also provides an overview and new analysis of international case safety reports for herbal medicines held in VigiBase (the World Health Organization's global database of individual case safety reports, maintained by the Uppsala Monitoring Centre). This book is aimed at pharmacists, doctors, nurses and other health professionals, herbal-medicine practitioners and organisations, herbal medicine and pharmaceutical industry personnel, pharmacovigilance specialists, medicines’ regulators, health and social science researchers and academics, pharmacovigilance and health professional students, and students of herbal and traditional medicine, throughout the world. It is an extremely valuable resource for all individuals whose work touches the intersection between herbal medicines and pharmacovigilance, and it provides both an introduction to the topic and a deeper, comprehensive, contemporary account of the topic.

Author: World Health Organization
Publisher:
ISBN: 9789241592215
Category : Drug monitoring
Languages : en
Pages : 18

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Book Description
Safety is a fundamental principle in the privision of herbal medicines and herbal products for health care and a critical component of quality control. These guidelines provide practical technical guidance for monitoring the safety of herbal medicines with pharmacovigilance systems.

Author: Subhash C. Mandal
Publisher: Springer Nature
ISBN: 9811581274
Category : Medical
Languages : en
Pages : 1135

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Book Description
The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine.

Author: Gerard Bodeker
Publisher: World Scientific
ISBN: 1860949134
Category : Medical
Languages : en
Pages : 472

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Book Description
This is the first book to address public health issues in traditional, complementary and alternative medicine (TCAM). It presents state-of-the-art reviews of TCAM research in a range of priority public health areas such as malaria and HIV and in such common ailments as skin conditions and orthopedic injury in developing countries. Contributions analyze policy trends in areas such as financing of TCAM and education and training in this field as well as selected case studies of model TCAM projects. Important chapters on research methodology, ethical and safety issues, and intellectual property rights pertaining to traditional medicine are also presented. Public financing for TCAM is a test of the commitment of governments, and the book includes an analysis from the World Health Organization's (WHO) Global Atlas data of the worldwide trends in this area. With safety concerns foremost in the minds of both policy makers and the public, the book offers a global overview of policy and legislative trends in this field as well as an important set of guidelines for pharmacovigilance and TCAM products. Sample Chapter(s). Chapter 1: Introduction (1,729 KB). Contents: Foreword (Allan Rosenfield); Policy: Introduction (Gerard Bodeker & Gemma Burford); Policy and Public Health Perspectives on Traditional, Complementary and Alternative Medicine: An Overview (Gerard Bodeker, Fredi Kronenberg & Gemma Burford); Financing Traditional, Complementary and Alternative Health Care Services and Research (Gemma Burford, Gerard Bodeker & Chi-Keong Ong); Training (Gerard Bodeker, Cora Neumann, Chi-Keong Ong & Gemma Burford); Safety: Issues and Policy (Gilbert Shia, Barry Noller & Gemma Burford); Pharmacovigilance of Herbal Medicines: A United Kingdom Perspective (Joanne Barnes); Medicinal Plant Biodiversity and Local Healthcare: Sustainable Use and Livelihood Development (Gerard Bodeker & Gemma Burford); Home Herbal Gardens OCo A Novel Health Security Strategy Based on Local Knowledge and Resources (G Hariramamurthi, P Venkatasubramanian, P M Unnikrishnan & D Shankar); Humanitarian Responses to Traditional Medicine for Refugee Care (Cora Neumann & Gerard Bodeker); Public-Private Partnerships: A Case Study from East Africa (Patrick Mbindyo); Public Health Issues: Priority Diseases and Health Conditions: Malaria (Merlin L Willcox & Gerard Bodeker); HIV/AIDS: Traditional Systems of Health Care in the Management of a Global Epidemic (Gerard Bodeker, Gemma Burford, Mark Dvorak-Little & George Carter); An Overview of Clinical Studies on Complementary and Alternative Medicine in HIV Infection and AIDS (Jianping Liu); Skin and Wound Care: Traditional, Complementary and Alternative Medicine in Public Health Dermatology (Gemma Burford, Gerard Bodeker & Terence J Ryan); Traditional Orthopaedic Practices: Beyond OCyBonesettingOCO (Gemma Burford, Gerard Bodeker & Jonathan Cohen); Research: Clinical Trial Methodology (Ranjit Roy Chaudhury, Urmila Thatte & Jianping Liu); Ethical Issues in Research (Merlin L Willcox, Gerard Bodeker & Ranjit Roy Chaudhury); Intellectual Property Rights (Gerard Bodeker); Epilogue (Gerard Bodeker & Gemma Burford). Readership: Public health specialists and departments; health policy departments in ministries of health and universities; colleges of traditional and complementary medicine; World Health Organization and affiliated institutions; medical schools as a background text on TCAM."

Author: Saikat Sen
Publisher: Springer Nature
ISBN: 9811372489
Category : Medical
Languages : en
Pages : 612

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Book Description
This book highlights the medical importance of and increasing global interest in herbal medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements, herbal cosmetics, etc. It also addresses various issues that are hampering the advancement of Indian herbal medicine around the globe; these include quality concerns and quality control, pharmacovigilance, scientific investigation and validation, IPR and biopiracy, and the challenge that various indigenous systems of medicine are at risk of being lost. The book also explores the role of traditional medicine in providing new functional leads and modern approaches that can offer elegant strategies for facilitating the drug discovery process. The book also provides in-depth information on various traditional medicinal systems in India and discusses their medical importance. India has a very long history of safely using many herbal drugs. Folk medicine is also a key source of medical knowledge and plays a vital role in maintaining health in rural and remote areas. Despite its importance, this form of medicine largely remains under-investigated. Out of all the traditional medicinal systems used worldwide, Indian traditional medicine holds a unique position, as it has continued to deliver healthcare throughout the Asian subcontinent since ancient times. In addition, traditional medicine has been used to derive advanced techniques and investigate many modern drugs. Given the scope of its coverage, the book offers a valuable resource for scientists and researchers exploring traditional and herbal medicine, as well as graduate students in courses on traditional medicine, herbal medicine and pharmacy.

Author: Pulok K. Mukherjee
Publisher: Elsevier
ISBN: 0323984568
Category : Business & Economics
Languages : en
Pages : 858

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Book Description
Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more

Author: José Luis Valverde
Publisher: IOS Press
ISBN: 9781586030056
Category : Business & Economics
Languages : en
Pages : 216

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Book Description
The main problem in the use of medicinal plants, discussed in this book, is that citizens are being persuaded that herbal medicine is based on its low or even absent toxicology. A good efficacy is assumed as self-evident, and therapeutic benefit without risks is expected. Many users prefer natural medicine instead of synthetic remedies. However, the number of reports on unwanted side effects of phytomedicines increased in the last years. In some instances, a lack of pharmaceutical quality was found. The unqualified recommendation of herbal medicines may represent a considerable risk to the user. The use of a herbal remedy with unproven efficacy can represent a risk for the user when a more effective and necessary treatment will therefore be stopped or omitted. These circumstances must be taken into account by the governments, inspection services, the doctors and the judges. The present approach to herbal medicines and fraud with these products do not receive the necessary punishment because it is believed that if the product does not have any therapeutic property, it cannot entail any harm either.

Author:
Publisher: World Health Organization
ISBN: 9240019146
Category : Medical
Languages : en
Pages : 85

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Book Description
This document provides information on the critical technical issues related to interactions between herbal medicines and other medicines for health-care professionals, regulators, researchers, pharmacovigilance centres, manufacturers and consumers. The intention of this document is to provide as much concise information as possible, and to give direction and guidance on capitalizing resources to support informed decision-making and maximize the safe concurrent use of herbal medicines and other medicines. The concepts of beneficial and harmful herb-drug interaction (HDI)s are introduced, with documented examples from the published literature. Types of HDI and their mechanisms are outlined, and the relevance of in vitro, general screening and in vivo tests is included. Challenges faced in evaluating and monitoring HDIs, data collection, assessment and dissemination of information are briefly discussed. The education and training of health professionals and consumers are addressed, together with potential research strategies for further investigation of the mechanisms, incidence, monitoring and management of HDIs.

Author: Pulok K. Mukherjee
Publisher: Elsevier
ISBN: 0128133988
Category : Science
Languages : en
Pages : 784

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Book Description
Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities

Author: Michael Heinrich
Publisher: Elsevier Health Sciences
ISBN: 0323834353
Category : Medical
Languages : en
Pages : 735

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Book Description
Pharmacognosy, the science of nature-derived drugs, pharmaceuticals and poisons, played a crucial role in the development of modern medicine, and now has an equally important place in healthcare all over the world. This wide scope ranges from traditional medicine systems and herbal and nutritional therapies, the preparation and use of highly standardised and clinically tested herbal medicines, to the production of potent drugs used only in a purified form. Natural sources mainly focus on plants, fungi and algae, but drug discovery of novel compounds and structures includes bacteria and even marine animals. Fundamentals of Pharmacognosy and Phytotherapy is a landmark textbook that covers this spectrum of medicinal plant use. Written by leading experts in this field, this book takes the reader through the history, identification and quality assurance of plant-based medicines to their therapeutic properties, safety and compatibility and interaction with prescribed drugs. Aimed at students of all healthcare professions, including pharmacy, medicine, nursing and complementary therapies, the comprehensively updated information in this textbook is also relevant to those companies and organisations concerned with the regulation and testing of herbal medicines (phytomedicines), other natural health products, nutraceuticals and dietary supplements. Introduces the concepts and scope of pharmacognosy Examines the scientific evidence of plant-based medicines for a range of health conditions Extended and updated referencing includes recent reviews, WHO and official documents (open access where available) for quick access to further scientific literature New to this edition Antimicrobial natural products: as antibiotics and antiseptics, and their potential as bacterial resistance modifiers Anticancer natural products: scope now includes their role in chemoprevention and associated anti-inflammatory mechanisms New chapter on pharmacovigilance for herbal medicines and related products Quality assurance and pharmacopoeial methods extended, with many new figures and examples Plant medicines of recent scientific interest (popularity, or notoriety) added throughout An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures, and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud Antimicrobial natural products: as antibiotics and antiseptics, and their potential as bacterial resistance modifiers Anticancer natural products: scope now includes their role in chemoprevention and associated anti-inflammatory mechanisms New chapter on pharmacovigilance for herbal medicines and related products Quality assurance and pharmacopoeial methods extended, with many new figures and examples Plant medicines of recent scientific interest (popularity, or notoriety) added throughout