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Author: Frederic Y M Wan Publisher: World Scientific ISBN: 9811256586 Category : Mathematics Languages : en Pages : 496
Book Description
Basic mathematical techniques for partial differential equations (PDE) with applications to the life sciences form an integral part of the core curriculum for programs in mathematical biology. Yet, students in such a program with an undergraduate training in biology are typically deficient in any exposure to PDE. This volume starts with simple first order PDE and progresses through higher order equations and systems but with interesting applications, even at the level of a single first order PDE with constant coefficients.Similar to the two previous volumes by the author, another unique feature of the book is highlighting the scientific theme(s) of interest for the biological phenomena being modelled and analysed. In addition to temporal evolution of a biological phenomenon, its limiting equilibrium states and their stability, the possibility of locational variations leads to a study of additional themes such as (signal and wave) propagation, spatial patterning and robustness. The requirement that biological developments are relatively insensitive to sustained environmental changes provides an opportunity to examine the issue of feedback and robustness not encountered in the previous two volumes of this series.
Author: Frederic Y M Wan Publisher: World Scientific ISBN: 9811256586 Category : Mathematics Languages : en Pages : 496
Book Description
Basic mathematical techniques for partial differential equations (PDE) with applications to the life sciences form an integral part of the core curriculum for programs in mathematical biology. Yet, students in such a program with an undergraduate training in biology are typically deficient in any exposure to PDE. This volume starts with simple first order PDE and progresses through higher order equations and systems but with interesting applications, even at the level of a single first order PDE with constant coefficients.Similar to the two previous volumes by the author, another unique feature of the book is highlighting the scientific theme(s) of interest for the biological phenomena being modelled and analysed. In addition to temporal evolution of a biological phenomenon, its limiting equilibrium states and their stability, the possibility of locational variations leads to a study of additional themes such as (signal and wave) propagation, spatial patterning and robustness. The requirement that biological developments are relatively insensitive to sustained environmental changes provides an opportunity to examine the issue of feedback and robustness not encountered in the previous two volumes of this series.
Author: National Research Council Publisher: National Academies Press ISBN: 0309095840 Category : Science Languages : en Pages : 163
Book Description
The exponentially increasing amounts of biological data along with comparable advances in computing power are making possible the construction of quantitative, predictive biological systems models. This development could revolutionize those biology-based fields of science. To assist this transformation, the U.S. Department of Energy asked the National Research Council to recommend mathematical research activities to enable more effective use of the large amounts of existing genomic information and the structural and functional genomic information being created. The resulting study is a broad, scientifically based view of the opportunities lying at the mathematical science and biology interface. The book provides a review of past successes, an examination of opportunities at the various levels of biological systemsâ€" from molecules to ecosystemsâ€"an analysis of cross-cutting themes, and a set of recommendations to advance the mathematics-biology connection that are applicable to all agencies funding research in this area.
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development Publisher: ISBN: Category : Federal aid to energy development Languages : en Pages : 1000
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development Publisher: ISBN: Category : Federal aid to energy development Languages : en Pages : 1060
Author: Karl Johan Åström Publisher: Princeton University Press ISBN: 069121347X Category : Technology & Engineering Languages : en Pages :
Book Description
The essential introduction to the principles and applications of feedback systems—now fully revised and expanded This textbook covers the mathematics needed to model, analyze, and design feedback systems. Now more user-friendly than ever, this revised and expanded edition of Feedback Systems is a one-volume resource for students and researchers in mathematics and engineering. It has applications across a range of disciplines that utilize feedback in physical, biological, information, and economic systems. Karl Åström and Richard Murray use techniques from physics, computer science, and operations research to introduce control-oriented modeling. They begin with state space tools for analysis and design, including stability of solutions, Lyapunov functions, reachability, state feedback observability, and estimators. The matrix exponential plays a central role in the analysis of linear control systems, allowing a concise development of many of the key concepts for this class of models. Åström and Murray then develop and explain tools in the frequency domain, including transfer functions, Nyquist analysis, PID control, frequency domain design, and robustness. Features a new chapter on design principles and tools, illustrating the types of problems that can be solved using feedback Includes a new chapter on fundamental limits and new material on the Routh-Hurwitz criterion and root locus plots Provides exercises at the end of every chapter Comes with an electronic solutions manual An ideal textbook for undergraduate and graduate students Indispensable for researchers seeking a self-contained resource on control theory
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development Publisher: ISBN: Category : Federal aid to energy development Languages : en Pages : 956
Author: Domitilla Del Vecchio Publisher: Princeton University Press ISBN: 1400850509 Category : Science Languages : en Pages : 287
Book Description
This book provides an accessible introduction to the principles and tools for modeling, analyzing, and synthesizing biomolecular systems. It begins with modeling tools such as reaction-rate equations, reduced-order models, stochastic models, and specific models of important core processes. It then describes in detail the control and dynamical systems tools used to analyze these models. These include tools for analyzing stability of equilibria, limit cycles, robustness, and parameter uncertainty. Modeling and analysis techniques are then applied to design examples from both natural systems and synthetic biomolecular circuits. In addition, this comprehensive book addresses the problem of modular composition of synthetic circuits, the tools for analyzing the extent of modularity, and the design techniques for ensuring modular behavior. It also looks at design trade-offs, focusing on perturbations due to noise and competition for shared cellular resources. Featuring numerous exercises and illustrations throughout, Biomolecular Feedback Systems is the ideal textbook for advanced undergraduates and graduate students. For researchers, it can also serve as a self-contained reference on the feedback control techniques that can be applied to biomolecular systems. Provides a user-friendly introduction to essential concepts, tools, and applications Covers the most commonly used modeling methods Addresses the modular design problem for biomolecular systems Uses design examples from both natural systems and synthetic circuits Solutions manual (available only to professors at press.princeton.edu) An online illustration package is available to professors at press.princeton.edu
Author: Susanna C Manrubia Publisher: World Scientific ISBN: 9814482951 Category : Science Languages : en Pages : 360
Book Description
' Synchronization processes bring about dynamical order and lead to spontaneous development of structural organization in complex systems of various origins, from chemical oscillators and biological cells to human societies and the brain. This book provides a review and a detailed theoretical analysis of synchronization phenomena in complex systems with different architectures, composed of elements with periodic or chaotic individual dynamics. Special attention is paid to statistical concepts, such as nonequilibrium phase transitions, order parameters and dynamical glasses. Contents:Synchronization and Clustering of Periodic Oscillators:Ensembles of Identical Phase OscillatorsHeterogeneous Ensembles and the Effects of NoiseOscillator NetworksArrays of Limit-Cycle OscillatorsSynchronization and Clustering in Chaotic Systems:Chaos and SynchronizationSynchronization in Populations of Chaotic ElementsClusteringDynamical GlassesSelected Applications:Chemical SystemsBiological CellsNeural Networks Readership: Graduate students and academics interested in complex systems. Keywords:Self-Organization;Nonlinear Dynamics;Chaos;Collective Synchronization;Dynamical Clustering;Hierarchical OrderReviews:“This book makes an additional contribution to the topic paying special attention to statistical concepts, such as nonequilibrium phase transitions, order parameters and dynamical glasses. Another distinguishing feature of the book is that it includes applications in chemistry, cell biology, and brain science.”Zentralblatt MATH '
Author: Pablo A. Iglesias Publisher: MIT Press ISBN: 0262013347 Category : Biological control systems Languages : en Pages : 359
Book Description
A survey of how engineering techniques from control and systems theory can be used to help biologists understand the behavior of cellular systems.
Author: Alan Garfinkel Publisher: Springer ISBN: 3319597310 Category : Mathematics Languages : en Pages : 445
Book Description
This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?
Author: Frederic Y M Wan
Author: Frederic Y M Wan
Author: National Research Council
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development
Author: Karl Johan Åström
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development
Author: Domitilla Del Vecchio
Author: Susanna C Manrubia
Author: Pablo A. Iglesias
Author: Alan Garfinkel