The Future of Human Healthspan

The Future of Human Healthspan PDF Author: The National Academies
Publisher: National Academies Press
ISBN: 0309178223
Category : Medical
Languages : en
Pages : 140

Book Description
An individual's healthspan can be defined as the length of time an individual is able to maintain good health. In 2007, over one hundred experts and researchers from public and private institutions across the nation convened to find new ways of addressing the human healthspan and the elusive nature of aging. Experts in public health, bioengineering, neuroscience and gerontology discussed how stress and lifestyle influence the decline of health at older ages. Other discussions focused on the integration of technology in the quality of life, gerontology, regenerative medicine and life expectancy with regard to social and behavioral traits. Still, other groups explored topics such as the cellular and molecular mechanisms of biological aging, the effects of exercise on the human healthspan, and changes in social context to enhance functional status of the elderly. Most importantly, experts agreed that it was imperative to ensure that the elderly have access to medical services by establishing relationships with health care and insurance providers.

The Healthspan Solution

The Healthspan Solution PDF Author: Raymond J. Cronise
Publisher: Penguin
ISBN: 1465497595
Category : Health & Fitness
Languages : en
Pages : 256

Book Description
Fancy optimizing your health and living a longer and fuller life with plant-based recipes? Then this may be the book for you! Looking to adopt a healthy vegetarian diet this New Year but don’t know where to start? No worries, we’ve got you covered! Authors and leading plant-based nutrition experts Julieanna Hever and Ray Cronise have spent over a decade researching diet and nutrition, analyzing longevity studies, and helping their clients achieve sustainable, lasting health benefits by adopting a whole-food, plant-based diet. So what are you waiting for? Dive straight in to discover: - 100 delicious and nutritious plant-based recipes for the whole family to love - Evidence-based research on the scientific underpinnings of the healthspan diet - Easy-to-follow guidelines simplify food choices without being restrictive - Beautifully photographed recipes offer options and flexibility In The Healthspan Solution, they share the simple and effective diet that has allowed their clients to lose weight, reverse disease, reduce or eliminate medication use, and achieve optimal health. This healthy recipe cookbook examines the health risks posed by typical Western eating habits and explains how a diet rich in vegetables, fruits, whole grains, legumes, mushrooms, nuts, seeds, herbs and spices can lead to lower blood pressure, a healthy gut, weight loss and longer life expectancy. Their flexible, customizable approach to eating challenges the conventional idea of breakfast, lunch, and dinner and focuses instead on soups, salads, sides, and sweets. With 100 delicious recipes to choose from, this healthy cookbook ensures that adopting a plant-based lifestyle is simple and sustainable. Still not sure? Check out our riveting reviews below and discover just how much The HealthSpan Solution has changed people’s lives for the better! “Ray and Julieanna didn’t write a fad diet book. It’s about making a permanent lifestyle transformation. The magic is I still can eat anything I want. The trick is what I want has profoundly changed. They did the trick for me and saved my life—now let them help you.”—Penn Jillette, Las Vegas entertainer and magician “Ray is a scientific visionary and Julieanna is a master of nutrition. Together they’ve written a fact-based recipe book for longevity that belongs in every kitchen. Buy it.”—David Sinclair, PhD, AO, Professor of Genetics, Harvard Medical School “Working with Julieanna and Ray has given me a profoundly new understanding of how food impacts health and how what we eat is often dictated by social influences. I’m excited to be a part of their effort to push to this message out to a far bigger audience.”—Cyan Banister, angel investor and entrepreneur “Julieanna and Ray are an incredible team. While others have sought to demonstrate the adequacy of an exclusively plant-sourced diet, they teach how it can be superior and mimics longevity research.”—Rich Roll, plant-powered ultra athlete and author

Age Later

Age Later PDF Author: Nir Barzilai, M.D.
Publisher: St. Martin's Press
ISBN: 1250230861
Category : Health & Fitness
Languages : en
Pages : 320

Book Description
How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties? Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s. One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers—individuals who maintain active lives well into their nineties and even beyond—and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline. In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye-opening and inspirational book will help you think of aging not as a certainty, but as a phenomenon—like many other diseases and misfortunes—that can be targeted, improved, and even cured.

Live Longer with AI

Live Longer with AI PDF Author: Tina Woods
Publisher: Packt Publishing Ltd
ISBN: 1838645942
Category : Computers
Languages : en
Pages : 603

Book Description
A wakeup call that shows us how to live our best and longest lives through the power of AI Key FeaturesDiscover how the latest cutting-edge developments in health and AI are helping us live longer, healthier, and better livesPersonalize your health, wealth and well-being using technology best suited to help you plan and build up your assets for a multi-stage lifeUnderstand how we can live our best lives in a post-COVID-19 world and equip ourselves for the next pandemic using technologyBook Description Live Longer with AI examines how the latest cutting-edge developments are helping us to live longer, healthier and better too. It compels us to stop thinking that health is about treating disease and start regarding it as our greatest personal and societal asset to protect. The book discusses the impact that AI has on understanding the cellular basis of aging and how our genes are influenced by our environment – with the pandemic highlighting the interconnectedness of human and planetary health. Author Tina Woods, founder and CEO of Collider Health and Collider Science, and the co-founder of Longevity International, has curated a panel of deeply insightful interviews with some of today’s brightest and most innovative thought leaders at the crossroads of health, technology and society. Read what leading experts in health and technology are saying about the book: "This is a handbook for the revolution!" —Sir Muir Gray, Director, Optimal Ageing "You can live longer and be happier if you make some changes – that is the theme of this book. Well-written and compelling." —Ben Page, CEO, Ipsos Mori "Tina's book is a must-read for those who want to discover the future of health." —José Luis Cordeiro, Fellow, World Academy of Art & Science; Director, The Millennium Project; Vice Chair, Humanity Plus; Co-Author of The Death of Death About the consultant editor Melissa Ream is a leading health and care strategist in the UK, leveraging user-driven design and artificial intelligence to design systems and support people to live healthier, longer lives. What you will learnDiscover how AI is changing the way we understand the wider determinants of health, how the environment influences our genes and why the solutions for living longer are linked to living greenerInform your perspective on how technology can deal with the health emergency in front of us – by minimizing health and wealth inequalitiesLearn why our “life data” is so important and how sharing it will help us develop aging “bio-markers”, enabling us to predict and manage dementia and other chronic diseases of agingFind out how scientists and doctors are using AI to find a vaccine for Covid-19, make us more resilient to future pandemic threats and pre-empt the next outbreakWho this book is for Professionals and general readers with an interest in learning how technology can and is being used to change our approach to aging and help us live longer and healthier lives. No prior knowledge of or experience with artificial intelligence is required.

The New Mobile Age

The New Mobile Age PDF Author: Joseph C. Kvedar
Publisher:
ISBN: 9780692906842
Category : Medical technology
Languages : en
Pages : 290

Book Description
Aging Baby Boomers want to grow old-and maintain their health-on their own terms. Digital technologies are creating a new kind of old, enabling individuals to remain vital, engaged and independent through their later years. But it has to be the right technology, designed for an aging population, not just what technologists and app developers think people want. Social robots, artificial intelligence, vocal biomarkers and facial decoding will analyze emotion, anticipate health problems, improve quality of life and enable better relationships with healthcare providers. Data can be used to better understand the 'soft science' of wellbeing and address the neglected crisis of caregiving. It's a business model but, more so, it's a new way of life. The New Mobile Age: How Technology Will Extend the Healthspan and Optimize the Lifespan explores the critical steps needed to achieve healthy longevity at a time when digital and connected health solutions are urgently needed to accommodate the aging of our population. Health tech innovations will not just improve healthcare for older adults, but will create a better and more responsive healthcare system for everyone.

Lifespan

Lifespan PDF Author: David A. Sinclair
Publisher: Atria Books
ISBN: 1501191977
Category : Science
Languages : en
Pages : 432

Book Description
A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

Explaining Divergent Levels of Longevity in High-Income Countries

Explaining Divergent Levels of Longevity in High-Income Countries PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309217105
Category : Social Science
Languages : en
Pages : 194

Book Description
During the last 25 years, life expectancy at age 50 in the United States has been rising, but at a slower pace than in many other high-income countries, such as Japan and Australia. This difference is particularly notable given that the United States spends more on health care than any other nation. Concerned about this divergence, the National Institute on Aging asked the National Research Council to examine evidence on its possible causes. According to Explaining Divergent Levels of Longevity in High-Income Countries, the nation's history of heavy smoking is a major reason why lifespans in the United States fall short of those in many other high-income nations. Evidence suggests that current obesity levels play a substantial part as well. The book reports that lack of universal access to health care in the U.S. also has increased mortality and reduced life expectancy, though this is a less significant factor for those over age 65 because of Medicare access. For the main causes of death at older ages -- cancer and cardiovascular disease -- available indicators do not suggest that the U.S. health care system is failing to prevent deaths that would be averted elsewhere. In fact, cancer detection and survival appear to be better in the U.S. than in most other high-income nations, and survival rates following a heart attack also are favorable. Explaining Divergent Levels of Longevity in High-Income Countries identifies many gaps in research. For instance, while lung cancer deaths are a reliable marker of the damage from smoking, no clear-cut marker exists for obesity, physical inactivity, social integration, or other risks considered in this book. Moreover, evaluation of these risk factors is based on observational studies, which -- unlike randomized controlled trials -- are subject to many biases.

Reviews on New Drug Targets in Age-Related Disorders

Reviews on New Drug Targets in Age-Related Disorders PDF Author: Paul C. Guest
Publisher: Springer Nature
ISBN: 303042667X
Category : Science
Languages : en
Pages : 340

Book Description
Aging is an inevitable part of life and is becoming a worldwide social, economic and health problem. This is mainly due to the fact that the increasing proportion of individuals in the advanced age category have a higher probability of developing age-related disorders, such as type II diabetes mellitus, cardiovascular disorders, sarcopenia, and neurodegenerative conditions. New therapeutic approaches are still needed to decrease or slow the effects of such diseases. Advances in -omic technologies, such as genomics, transcriptomics, proteomics and metabolomics, have significantly advanced our understanding of disease in multiple medical areas, as the analysis of multiple molecular networks has simultaneously provided a more integrated view of disease pathways. It is hoped that emerging hits from these analyses might be prioritized for further screening as potential novel drug targets for increasing the human healthspan in line with the lifespan. In turn, this will lead to new therapeutic strategies as well as drug development projects by the pharmaceutical industry. This book presents a series of reviews describing studies that have resulted in identification of new potential drug targets for age-related disorders. Much of this information has come from -omic comparisons of healthy and disease states or from testing the effects of new therapeutic approaches. Authored by experts from around the globe, each chapter is presented in the context of specific chronic diseases or therapeutic strategies. This book is designed for researchers in the areas of aging and chronic disease, as well as clinical scientists, physicians and stakeholders in major drug companies.

Ending Aging

Ending Aging PDF Author: Aubrey de Grey
Publisher: Macmillan + ORM
ISBN: 1429931833
Category : Science
Languages : en
Pages : 452

Book Description
MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Advances in Geroscience

Advances in Geroscience PDF Author: Felipe Sierra
Publisher: Springer
ISBN: 3319232460
Category : Medical
Languages : en
Pages : 622

Book Description
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.