Folic Acid Metabolism in Health and Disease PDF Download

Author: Mary Frances Picciano
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 320

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Book Description
Abstract: This publication provides a background on the biochemistry and physiology of folic acid and discusses recent developments in analytical methodology and the clinical aspects of folic acid nutrition. Topics include: an historical account of the advances in the biochemistry and function of folic acid; the regulation of folic acid metabolism and the use of antagonists to study folate metabolism and transport by cells; the intestinal absorption of dietary folates; microbiological growth techniques; ani mal bioassays for measuring bioavailability of food folates; clinical aspects of dietary, physiological, and deficiency concerns; and the evaluation of folate nutritional status in infants, adolescents, adults, and other population groups.

Author: Lynn B. Bailey
Publisher: CRC Press
ISBN: 1420071254
Category : Medical
Languages : en
Pages : 602

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Book Description
During the fifteen years since the bestselling first edition of Folate in Health and Disease was published, there have been thousands of new research studies related to folate and its role in health and disease. The second edition of the book uniquely bridges the gap between basic science and public health/clinical medicine.Presents Groundbreaking

Author: Edward J. Massaro
Publisher: Springer Science & Business Media
ISBN: 1592591647
Category : Medical
Languages : en
Pages : 365

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Book Description
Folic acid not only helps to prevent a variety of serious neural-tube birth defects-among them anencephaly and spina bifida-but is also an important factor in general human health. In Folate and Human Development, an authoritative panel of basic and clinical researchers critically reviews the latest findings on the role of folate in human development, health, and disease. Specific areas addressed include folate metabolism in zinc or copper deficiencies, choline and folate in development, animal models of folate-related birth defects, developmental toxicants potentially acting via folate perturbation, and folate's role in vascular disease in women. There are also cutting-edge discussions of genes and neural tube development, folate receptor polymorphism and the risk for neural defects, abnormal DNA synthesis and methylation with folate/methyl insufficiency, and folic acid and homocysteine as risk factors for neural-tube defects. Comprehensive and up-to-date, Folate and Human Development critically evaluates our current understanding of the role of folates in human health and disease, offering biomedical and clinical researchers a deeper understanding of the folate and nutrient basis of neural-tube defects.

Author: Stephen M. Lee
Publisher:
ISBN: 9781536118353
Category : Medical
Languages : en
Pages : 180

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Book Description
This book reviews and discusses the most relevant epidemiological aspects of OFCs and its prevention. It evaluates the role of folate and other factors in preventing OFC by analysing the health and socio-demographic data collected from a population sample. Individuals that are deficient in folates are suggested to have increase vulnerability to disease, including neurological conditions. Folates are involved in the metabolism of homocysteine which is a sulfur containing non-protein amino acid. This book will also highlight the recent advances made in understanding the effect of dietary folic acid over supplementation on neurological function. Patients with low levels of folic acid and other B vitamins, metabolism disorders, and renal failure have frequently high homocysteine levels that have been especially associated with cardiovascular and bone disease. This book reviews and analyzes the most important results about the effects of folic acid supplementation on clinical targets and it focuses on the effects of folic acid therapy on clinical outcomes of chronic renal failure patients with high homocysteine levels.

Author: Brendan Lee
Publisher: Oxford Monographs on Medical G
ISBN: 0199797587
Category : Medical
Languages : en
Pages : 393

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Book Description
This volume is an expansion on the known treatment model of IEMs, one that establishes an innovative pathway approach and provides a new authority on this family of disease. Alongside the standard cadre of molecular and clinical underpinnings, this book includes coverage of newborn screening and an overarching treatment of IEMs as complex diseases.

Author: Martin Kohlmeier
Publisher: Elsevier
ISBN: 0080537898
Category : Technology & Engineering
Languages : en
Pages : 840

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Book Description
Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source. Key Features * Highly illustrated with relevant chemical structures and metabolic pathways * Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry * First comprehensive work on the subject

Author: William L. Bruneau
Publisher: WB Publisher
ISBN: 9780974879918
Category :
Languages : en
Pages : 128

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Book Description
Folic Acid is clearly written in language that is easily understood by the average reader. While solidly based on peer-reviewed research, this book is a very readable, basic primer for anyone who wants the benefits of improved health and longevity. It is our humble opinion that even health professionals could benefit greatly from referring to this absolutely up-to-date summation of all relevant published research through November, 2006. Folic acid is the popular synthetic form, the term folate referes to all members of this vitamin family. Folates are best known for theirimportance in avoiding birth defects, but research in the last few years has established that they are absolutely essential for everyone's health and well-being. They are now known to be crucial for the proper functioning of your cells and your genes.Various scientific studies claim that anywhere from 10% to 67% of us (men, women, and children) are deficient in folate and at risk for many deficiency diseases. Young women of child-bearing age have the greatest need and paradoxically tend to have low levels of folate - even after food fortification!Folic Acid (the book) contains everything you need to know about this crucial vitamin. Fully up-to-date, it is based on the latest scientific research. This book describes what folates are, what they do to your body, and how and why they are crucial for your health and longevity. This book describes folate's many health benefits, and an impressive list of diseases and conditions caused by a folate deficiency in your body. How much to take for optimum health is described. Current research questions the adequacy of the current Recommended Daily Allowances. A central theme of this book is to help determine what is adequate - which varies significantly and is probably different for any given reader. Homocysteine is also explained in this book - what it is and why abnormal levels have become such a concern to health professionals. While folic acid is the largest single determinant of your homocysteine level, this book clearly describes the other known factors that affect your level of homocysteine. The relevance of recently discovered mutations in crucial genes that govern the folate metabolism are also covered.Throughout this book are "scorecards" that visually summarize the known evidence for such topics as "Who is Deficient?" or "What is Average?"

Author: María Chávarri Hueda
Publisher: BoD – Books on Demand
ISBN: 9535134396
Category : Science
Languages : en
Pages : 320

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Book Description
In recent years, the concern of society about how food influences the health status of people has increased. Consumers are increasingly aware that food can prevent the development of certain diseases, so in recent years, the food industry is developing new, healthier products taking into account aspects such as trans fats, lower caloric intake, less salt, etc. However, there are bioactive compounds that can improve the beneficial effect of these foods and go beyond the nutritional value. This book provides information on impact of bioactive ingredients (vitamins, antioxidants, compounds of the pulses, etc.) on nutrition through food, how functional foods can prevent disease, and tools to evaluate the effects of bioactive ingredients, functional foods, and diet.

Author: Great Britain. Committee on Medical Aspects of Food and Nutrition Policy
Publisher: Stationery Office Books (TSO)
ISBN:
Category : Conception
Languages : en
Pages : 128

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Book Description
This COMA report reviews available evidence linking dietary folate and folic acid with human health. It is concerned particularly with the need for adequate intakes of folate at the time of conception to reduce the risk of a pregnancy being affected by neural tube defect (NTD).

Author: Joseph I. Boullata
Publisher: Springer Science & Business Media
ISBN: 160327362X
Category : Science
Languages : en
Pages : 824

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Book Description
Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In the five years since publication of the first edition of the Handbook of Drug-Nutrient Interactions new perspectives have emerged and new data have been generated on the subject matter. Providing both the scientific basis and clinical relevance with appropriate recommendations for many interactions, the topic of drug-nutrient interactions is significant for clinicians and researchers alike. For clinicians in particular, the book offers a guide for understanding, identifying or predicting, and ultimately preventing or managing drug-nutrient interactions to optimize patient care. Divided into six sections all chapters have been revised or are new to this edition. Chapters balance the most technical information with practical discussions and include outlines that reflect the content; discussion questions that can guide the reader to the critical areas covered in each chapter, complete definitions of terms with the abbreviation fully defined and consistent use of terms between chapters. The editors have performed an outstanding service to clinical pharmacology and pharmaco-nutrition by bringing together a multi-disciplinary group of authors. Handbook of Drug-Nutrient Interactions, Second Edition is a comprehensive up-to-date text for the total management of patients on drug and/or nutrition therapy but also an insight into the recent developments in drug-nutrition interactions which will act as a reliable reference for clinicians and students for many years to come.