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Microbial Diversity in the Genomic Era

Microbial Diversity in the Genomic Era PDF Author: Surajit Das
Publisher: Elsevier
ISBN: 0443133212
Category : Science
Languages : en
Pages : 840

Book Description
Microbial Diversity in the Genomic Era, Second Edition presents techniques used for microbial taxonomy and phylogeny, along with their applications and respective strengths and challenges. Though many advanced techniques for the identification of unknown bacterium are available in the genomic era, a far fewer number of the total microbial species have been discovered and identified to date. With that in mind, this book incorporates recently developed biosystematics methods and approaches to assess microbial taxonomy, with suitable recommendations for where to apply them across the range of bacterial identification and infectious disease research. Here, international researchers in the field first provide a broad overview of microbial genomics research and microbiome directed medicine, followed by sections on molecular tools for microbial diversity research, extremophilic microbial diversity, functional microbial diversity across application areas, microbial diversity and infectious disease research, and future directions for research. Step-by-step methodologies are provided for key techniques, along with applied case studies breaking down recent research studies into the practical components, illuminating pathways for new studies across the field. This new edition has been fully updated to address advances in the field of microbiome directed medicine, and whole genome sequencing for studying microbial diversity, considering both recent technological advances and new applications areas, from extremophile studies to the latest approaches in human microbiome analysis. Instructs in techniques used for microbial taxonomy and phylogeny, with discussions of their applications and respective pros and cons Reviews the evolving field of microbial typing and the genomic technologies that enable comparative metagenomic analysis of complex microbial environments Covers microbiome directed translational research, as well as whole genome sequencing for studying microbial diversity, with newly added research protocols and case studies Reviews future applications in the field of microbiome directed medicine Features chapter contributions from global experts in the field

Microbial Diversity in the Genomic Era

Microbial Diversity in the Genomic Era PDF Author: Surajit Das
Publisher: Elsevier
ISBN: 0443133212
Category : Science
Languages : en
Pages : 840

Book Description
Microbial Diversity in the Genomic Era, Second Edition presents techniques used for microbial taxonomy and phylogeny, along with their applications and respective strengths and challenges. Though many advanced techniques for the identification of unknown bacterium are available in the genomic era, a far fewer number of the total microbial species have been discovered and identified to date. With that in mind, this book incorporates recently developed biosystematics methods and approaches to assess microbial taxonomy, with suitable recommendations for where to apply them across the range of bacterial identification and infectious disease research. Here, international researchers in the field first provide a broad overview of microbial genomics research and microbiome directed medicine, followed by sections on molecular tools for microbial diversity research, extremophilic microbial diversity, functional microbial diversity across application areas, microbial diversity and infectious disease research, and future directions for research. Step-by-step methodologies are provided for key techniques, along with applied case studies breaking down recent research studies into the practical components, illuminating pathways for new studies across the field. This new edition has been fully updated to address advances in the field of microbiome directed medicine, and whole genome sequencing for studying microbial diversity, considering both recent technological advances and new applications areas, from extremophile studies to the latest approaches in human microbiome analysis. Instructs in techniques used for microbial taxonomy and phylogeny, with discussions of their applications and respective pros and cons Reviews the evolving field of microbial typing and the genomic technologies that enable comparative metagenomic analysis of complex microbial environments Covers microbiome directed translational research, as well as whole genome sequencing for studying microbial diversity, with newly added research protocols and case studies Reviews future applications in the field of microbiome directed medicine Features chapter contributions from global experts in the field

Microbial Diversity and Bioprospecting

Microbial Diversity and Bioprospecting PDF Author: Alan T. Bull
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 532

Book Description
Presents the diverse and complex sets of technology, data, knowledge, ideas, and objectives into an integrated and holistic approach to bioprospecting. * Explores the primacy of natural products for biotechnology, emphasizing the extraordinary resource that microbial diversity presents and how and where that resource, and the exploitable properties that it contains, can be found. * Demonstrates the need for modern microbiologists to have an integrated perspective of science in order to address the big questions in microbiology. * Serves as a reference for instructors and researchers in environmental microbiology, biotechnology, and microbial diversity as well as applied biologists.

Recent Advancements in Microbial Diversity

Recent Advancements in Microbial Diversity PDF Author: Surajit de Mandal
Publisher: Academic Press
ISBN: 0128212667
Category : Science
Languages : en
Pages : 624

Book Description
Microorganisms are a major part of the Earth’s biological diversity. Although a lot of research has been done on microbial diversity, most of it is fragmented. This book creates the need for a unified text to be published, full of information about microbial diversity from highly reputed and impactful sources. Recent Advancements in Microbial Diversity brings a comprehensive understanding of the recent advances in microbial diversity research focused on different bodily systems, such as the gut. Recent Advancements in Microbial Diversity also discusses how the application of advanced sequencing technologies is used to reveal previously unseen microbial diversity and show off its function. Gives insight into microbial diversity in different bodily systems Explains novel approaches to studying microbial diversity Highlights the use of omics to analyze the microbial community and its functional attributes Discusses the techniques used to examine microbial diversity, including their applications and respective strengths and weaknesses

Microbial Evolution

Microbial Evolution PDF Author: Howard Ochman
Publisher:
ISBN: 9781621820376
Category : Science
Languages : en
Pages : 0

Book Description
Bacteria have been the dominant forms of life on Earth for the past 3.5 billion years. They rapidly evolve, constantly changing their genetic architecture through horizontal DNA transfer and other mechanisms. Consequently, it can be difficult to define individual species and determine how they are related. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines how bacteria and other microbes evolve, focusing on insights from genomics-based studies. Contributors discuss the origins of new microbial populations, the evolutionary and ecological mechanisms that keep species separate once they have diverged, and the challenges of constructing phylogenetic trees that accurately reflect their relationships. They describe the organization of microbial genomes, the various mutations that occur, including the birth of new genes de novo and by duplication, and how natural selection acts on those changes. The role of horizontal gene transfer as a strong driver of microbial evolution is emphasized throughout. The authors also explore the geologic evidence for early microbial evolution and describe the use of microbial evolution experiments to examine phenomena like natural selection. This volume will thus be essential reading for all microbial ecologists, population geneticists, and evolutionary biologists.

The Chemistry of Microbiomes

The Chemistry of Microbiomes PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309458390
Category : Science
Languages : en
Pages : 133

Book Description
The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.

Uncultivated Microorganisms

Uncultivated Microorganisms PDF Author: Slava S. Epstein
Publisher: Springer Science & Business Media
ISBN: 3540854657
Category : Medical
Languages : en
Pages : 215

Book Description
In 1898, an Austrian microbiologist Heinrich Winterberg made a curious observation: the number of microbial cells in his samples did not match the number of colonies formed on nutrient media (Winterberg 1898). About a decade later, J. Amann qu- tified this mismatch, which turned out to be surprisingly large, with non-growing cells outnumbering the cultivable ones almost 150 times (Amann 1911). These papers signify some of the earliest steps towards the discovery of an important phenomenon known today as the Great Plate Count Anomaly (Staley and Konopka 1985). Note how early in the history of microbiology these steps were taken. Detecting the Anomaly almost certainly required the Plate. If so, then the period from 1881 to 1887, the years when Robert Koch and Petri introduced their key inventions (Koch 1881; Petri 1887), sets the earliest boundary for the discovery, which is remarkably close to the 1898 observations by H. Winterberg. Celebrating its 111th anniversary, the Great Plate Count Anomaly today is arguably the oldest unresolved microbiological phenomenon. In the years to follow, the Anomaly was repeatedly confirmed by all microb- logists who cared to compare the cell count in the inoculum to the colony count in the Petri dish (cf., Cholodny 1929; Butkevich 1932; Butkevich and Butkevich 1936). By mid-century, the remarkable difference between the two counts became a universally recognized phenomenon, acknowledged by several classics of the time (Waksman and Hotchkiss 1937; ZoBell 1946; Jannasch and Jones 1959).

Bioprospecting of Microbial Diversity

Bioprospecting of Microbial Diversity PDF Author: Pradeep Verma
Publisher: Elsevier
ISBN: 0323885756
Category : Technology & Engineering
Languages : en
Pages : 566

Book Description
Bioprospecting of Microbial Diversity: Challenges and Applications in Biochemical Industry, Agriculture and Environment Protection gives a detailed insight into the utilization of microorganisms or microorganism-based bioactive compounds for the development of sustainable approaches, covering recent advances and challenges in the production and recovery of bioactive compounds such as enzymes, biopesticides, biofertilizers, biosensors, therapeutics, nutraceutical and pharmaceutical products. The challenges associated with the different approaches of microbial bioprospecting along with possible solutions to overcome these limitations are addressed. Further, the application of microbe-based products in the area of environmental pollution control and developing greener technologies are discussed. Providing valuable insight into the basics of microbial prospecting, the book covers established knowledge as well as genomic-based technological advancements to offer a better understanding of its application to various industries, promoting the commercialization of microbial-derived bioactive compounds and their application in biochemical industries, agriculture, and environmental protection studies. Describes the advanced techniques available for microbial bioprospecting for large-scale industrial production of bioactive compounds Presents recent advances and challenges for the application of microbe-based products in agriculture and environment pollution control Provides knowledge of microbial production of bioenergy and high-value compounds such as nutraceuticals and pharmaceuticals

Science Needs for Microbial Forensics

Science Needs for Microbial Forensics PDF Author: National Research Council (U.S.). Committee on Science Needs for Microbial Forensics: Developing an Initial International Roadmap
Publisher:
ISBN: 9780309302456
Category : Law
Languages : en
Pages : 0

Book Description
For these reasons, building awareness of and capacity in microbial forensics can assist in our understanding of what may have occurred during a biothreat event, and international collaborations that engage the broader scientific and policy-making communities are likely to strengthen our microbial forensics capabilities. One goal would be to create a shared technical understanding of the possibilities--and limitations--of the scientific bases for microbial forensics analysis. Science Needs for Microbial Forensics: Developing Initial International Research Priorities, based partly on a workshop held in Zabgreb, Croatia in 2013, identifies scientific needs that must be addressed to improve the capabilities of microbial forensics to investigate infectious disease outbreaks and provide evidence of sufficient quality to support legal proceedings and the development of government policies.

Microbial Diversity

Microbial Diversity PDF Author: T. Satyanarayana
Publisher: I. K. International Pvt Ltd
ISBN: 8188237434
Category : Microbial diversity
Languages : en
Pages : 1159

Book Description
Microbial Diversity: Current Perspectives and Potential Applications is woven around the recent global perceptions of microbial diversity in its all embracing facets. Diversity perspectives are discussed in the context of ecosystem dynamics, taking into consideration environments that are rather unique to microorganisms. Considerable thrust is placed on the role that microorganisms play in sustainable production systems. Microbe-plant interaction arena is highlighted through the discussion of mycorrhizal partners, on which depends not only the plant community structure but also abatement of abiotic and biotic stresses. Other mutualist, rhizobia gets its due coverage whereas plant disease component carries examples from both, fungal and viral disease point of view. Considerable emphasis is placed on a discussion of the environmental issues such as the approaches that will lead to newer bioremediation technologies. No discussion of microbial diversity is complete without their implications in animal and human health. Discussed in this context are L-arginases in cancer therapy as also bioactives from cyanobacteria. Genomics and pathogenicity of two groups of viruses, viz., blue tongue and flaviviruses is highlighted whereas keratinophilic fungal forms are discussed in the context of dermatophytic infections. This volume also carries a fair number of articles on commercial microbiology.

Soil Biological Communities and Ecosystem Resilience

Soil Biological Communities and Ecosystem Resilience PDF Author: Martin Lukac
Publisher: Springer
ISBN: 3319633368
Category : Technology & Engineering
Languages : en
Pages : 347

Book Description
This volume explores current knowledge and methods used to study soil organisms and to attribute their activity to wider ecosystem functions. Biodiversity not only responds to environmental change, but has also been shown to be one of the key drivers of ecosystem function and service delivery. Soil biodiversity in tree-dominated ecosystems is also governed by these principles, the structure of soil biological communities is clearly determined by environmental, as well as spatial, temporal and hierarchical factors. Global environmental change, together with land-use change and ecosystem management by humans, impacts the aboveground structure and composition of tree ecosystems. Due to existing knowledge of the close links between the above- and belowground parts of terrestrial ecosystems, we know that soil biodiversity is also impacted. However, very little is known about the nature of these impacts; effects on the overall level of biodiversity, the magnitude and diversity of functions soil biodiversity generates, but also on the present and future stability of tree ecosystems and soils. Even though much remains to be learned about the relationships between soil biodiversity and tree ecosystem functionality, it is clear that better effort needs to be made to describe and understand key processes which take place in soils and are driven by soil biota.