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Author: Franz Joel Leong Publisher: CRC Press ISBN: 9781439835302 Category : Medical Languages : en Pages : 236
Book Description
An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientists, and doctors working, learning, and teaching in the field of TB. It contains 100 color photographs and illustrations that bring clarity to the information presented. The atlas takes the unusual approach of covering multiple species histopathology, arguably the first and quite possibly the only resource to do so. It provides a simple, annotated, and visual presentation of the comparative histopathology of TB in human and animal models. The editors have compiled information that helps TB scientists to distinguish between the features of all major animal models available and to use them with their strengths and limitations in mind. The book provides guidance for selecting the best animal model(s) to answer specific questions and to test the efficacy of drug candidates.
Author: Franz Joel Leong Publisher: CRC Press ISBN: 9781439835302 Category : Medical Languages : en Pages : 236
Book Description
An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientists, and doctors working, learning, and teaching in the field of TB. It contains 100 color photographs and illustrations that bring clarity to the information presented. The atlas takes the unusual approach of covering multiple species histopathology, arguably the first and quite possibly the only resource to do so. It provides a simple, annotated, and visual presentation of the comparative histopathology of TB in human and animal models. The editors have compiled information that helps TB scientists to distinguish between the features of all major animal models available and to use them with their strengths and limitations in mind. The book provides guidance for selecting the best animal model(s) to answer specific questions and to test the efficacy of drug candidates.
Author: Rakesh K Gupta Publisher: Jaypee Brothers Medical Publishers ISBN: 9388958977 Category : Medical Languages : en Pages : 279
Book Description
Key Features ? The book is a compilation of various facets of imaging in tuberculosis with special emphasis on its clinicopathological correlation ? Also covers important aspects of tuberculosis like epidemiology, clinical perspective and management ? Includes designated chapters on extrapulmonary tuberculosis involving the central nervous system, spine, head and neck, lymph nodes, abdomen, urogenital system and bones and joints ? Written by experts well known for their academic inclination and capability ? The book is a valuable resource for pulmonologists, physicians and postgraduate students.
Author: Petros C. Karakousis Publisher: Springer Nature ISBN: 3030569055 Category : Medical Languages : en Pages : 325
Book Description
This book discusses specific immune cell regulatory pathway(s), immune cell types, or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT). The pathways/mechanisms investigated are either protective – thus calling for pathway/factor enhancing drugs – or maladaptive – thus calling for pathway/factor inhibitory drugs. Discovery and development (pre-clinical and clinical) of candidate HDT agents will also be elucidated, as well as approaches for HDT of other diseases. The benefit to the reader will derive from learning about the biology of multiple host pathways involved in health and disease, how these pathways are disrupted or dysregulated during tuberculosis, and which druggable targets exist in these pathways. This book provides the reader with a roadmap of current and future directions of HDT against tuberculosis. Since the host pathways/factors involved in protective or maladaptive responses to tuberculosis are not disease-specific, information learned from the context of tuberculosis likely will be relevant to other infectious and non-infectious diseases.
Author: Agustín Fuentes Publisher: John Wiley & Sons ISBN: 0470673370 Category : Social Science Languages : en Pages : 1596
Book Description
The International Encyclopedia of Primatology represents the first comprehensive encyclopedic reference focusing on the behaviour, biology, ecology, evolution, genetics, and taxonomy of human and non-human primates. Represents the first comprehensive encyclopedic reference relating to primatology Features more than 450 entries covering topics ranging from the taxonomy, history, behaviour, ecology, captive management and diseases of primates to their use in research, cognition, conservation, and representations in literature Includes coverage of the basic scientific concepts that underlie each topic, along with the latest advances in the field Highly accessible to undergraduate and graduate students in primatology, anthropology, and the medical, biological and zoological sciences Essential reference for academics, researchers and commercial and conservation organizations This work is also available as an online resource at www.encyclopediaofprimatology.com
Author: Mohamed Fethi Ladeb Publisher: Springer Nature ISBN: 3031070402 Category : Medical Languages : en Pages : 371
Book Description
This book provides an extensive overview of the role of imaging in the detection, diagnosis, management, and follow-up of tuberculosis. Chapters cover the disease's epidemiology and pathophysiology, microbiological diagnosis and pathology relevant to radiologists, and the distinct aspects of imaging tuberculosis at various locations and body systems. This book discusses recent advances in imaging pertaining to tuberculosis, and addresses the approach to patients with tuberculosis and HIV co-infection. The final chapter offers an algorithmic approach to the diagnosis and management steps of tuberculosis. Imaging of Tuberculosis is an updated and comprehensive reference source that covers imaging of tuberculosis in a structured fashion and is valuable for radiologists.
Author: Harshini Mukundan Publisher: CABI ISBN: 1780643969 Category : Medical Languages : en Pages : 587
Book Description
Mycobacteria are bacterial pathogens which cause diseases in humans and non-human animals. This monograph will primarily cover the most important and widely researched groups of mycobacteria: members of the Mycobacterium tuberculosis complex (MTC) and Mycobacterium leprae, across a wide range of host species. M. tuberculosis and M. bovis are particularly relevant with the increasing drug resistance and co-infection with HIV associated with M. tuberculosis and the possible cross-infection of badgers and cattle associated with M. bovis. This book will provide a reference for researchers working in different fields creating a work which draws together information on different pathogens, and by considering the diseases in a zoonotic context provides a One Health approach to these important groups of diseases.
Author: Suzie Hingley-Wilson Publisher: Frontiers Media SA ISBN: 2832519164 Category : Medical Languages : en Pages : 297
Book Description
The macrophage (or “big eater”) is often considered the first cell type to encounter the causative agent of Tuberculosis (TB), Mycobacterium tuberculosis, upon entry to the lung. Once inside the macrophage the tubercle bacillus can survive and even replicate where many other invading pathogens perish. Recent research suggests the bacilli adapts within this hostile environment, treating the macrophage like a Trojan horse. Indeed, cutting-edge techniques have revealed that the degree of bacterial heterogeneity and resistance to antibiotics changes within the macrophage. M. tuberculosis spends most of its life cycle within the macrophage and has adopted specific mechanisms to survive, egress and to recruit more of this niche cell (eg the Type VII secretion system ESX-1). Understanding the host-pathogen interaction in tuberculous infection is key to understanding TB, which remains the number one cause of death from a bacterial infection. In this research topic we aim to cover advances in understanding how the tubercle bacillus adapts and survives within the host cell. Determining the responsible mechanisms may reveal novel ways to target this deadly pathogen and halt its adaptation and transformation within these potentially destructive or permissive cells.
Author: Elliott R. Jacobson Publisher: CRC Press ISBN: 1420004034 Category : Medical Languages : en Pages : 732
Book Description
Far from the line drawings and black-and-white photos of the past, Infectious Diseases and Pathology of Reptiles features high-quality, color photos of normal anatomy and histology, as well as gross, light, and electron microscopic images of pathogens and diseases. Many of these images have never before been published, and come directly from
Author: Franz Joel Leong
Author: Franz Joel Leong
Author: Philip T. Cagle
Author: Qing Pan
Author: Rakesh K Gupta
Author: Petros C. Karakousis
Author: Agustín Fuentes
Author: Mohamed Fethi Ladeb
Author: Harshini Mukundan
Author: Suzie Hingley-Wilson
Author: Elliott R. Jacobson