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Author: Lynn M. Schnapp Publisher: Humana Press ISBN: 3319465279 Category : Medical Languages : en Pages : 185
Book Description
Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies.
Author: Lynn M. Schnapp Publisher: Humana Press ISBN: 3319465279 Category : Medical Languages : en Pages : 185
Book Description
Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies.
Author: Didier Dreyfuss Publisher: CRC Press ISBN: 1420019260 Category : Medical Languages : en Pages : 776
Book Description
This reference surveys current best practices in the prevention and management of ventilator-induced lung injury (VILI) and spans the many pathways and mechanisms of VILI including cell injury and repair, the modulation of alveolar-capillary barrier properties, and lung and systemic inflammatory consequences of injurous mechanical ventilation. Considering many emerging therapeutic options, this guide also reviews the wide array of clinical studies on lung protection strategies and approaches to ARDS patients at risk for VILI.
Author: Sadis Matalon Publisher: IOS Press ISBN: 9781586031831 Category : Lungs Languages : en Pages : 320
Book Description
This book contains contributions of internationally known basic scientists and clinicians with expertise in various aspects of lung injury and repair. This monogram on the pathophysiology and treatment of Acute Lung Injury contains five different sections, each one with contributions from both basic and clinical scientists, outlining existing controversies, an how they can be resolved by future multidisciplinary studies. The various sections discuss: sodium transport and fluid clearance across the normal and injured lungs, the role of the pulmonary surfactant in the pathogenesis and treatment of ARDS, mechanisms and modification of acute and chronic lung injury, ventilatory strategies for the management of acute respiratory distress syndrome and nitric oxide: friend or foe.
Author: Ronald G. Crystal Publisher: Lippincott Williams & Wilkins ISBN: Category : Interventional radiology Languages : en Pages : 424
Book Description
A comprehensive review of lung injury, defence and repair and therapeutic interventions. The text focuses on clinically relevant issues such as infections and host defences, immune injury, airborne contaminants, acute lung injury, injury from drugs, fibrotic processes and genetic modulation.
Author: Robert H. Notter Publisher: CRC Press ISBN: 9780824757939 Category : Medical Languages : en Pages : 888
Book Description
Progressing from general scientific principles and concepts to in-depth topical discussions of current research and treatment methods, this comprehensive reference defines the cellular and molecular mechanisms contributing to inflammatory lung injury and repair. Extensive coverage is provided on key mediators and pathways important in acute and chronic pulmonary inflammation and lung injury, as well as the mechanistic pathophysiology of related diseases ranging from clinical acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) to idiopathic pulmonary fibrosis (IPF) and other subacute and chronic conditions. Additional chapters also address vascular dysfunction, surfactant dysfunction, reactive oxygen/nitrogen species, and cell and animal models of acute and chronic lung injury.
Author: Michael Kasper Publisher: ISBN: 9783039431663 Category : Languages : en Pages : 222
Book Description
Alveolar epithelial cells (AECs) of the lung are important contributors to pulmonary immune functions and to pulmonary development and alveolar repair mechanisms following lung injury. AECI, together with the capillary endothelium, form the extremely thin barrier between alveolar air and blood. AECII produce and metabolize the surface-tension lowering and immune-modulating surfactant and are the progentiors of AECI. A great variety of processes rely on their normal functioning, including maintenance of the alveolar barrier; innate immune defense; and processes of differentiation, senescence, apoptosis, and autophagy. The wide range of AEC functions is nicely reflected by the diversity of topics addressed by the four review and eight original articles contained in this Special Issue of the International Journal of Molecular Sciences. Beyond the broad spectrum of topics, the authors of this issue also made use of an impressive variety of analytical methods, thus further illustrating the fascinating diversity of aspects related to AEC biology.
Author: Venkataramana K Sidhaye Publisher: Academic Press ISBN: 0128038810 Category : Medical Languages : en Pages : 276
Book Description
Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences
Author: Zhao-fan Xia Publisher: Springer Nature ISBN: 9811570566 Category : Medical Languages : en Pages : 183
Book Description
This book provides in-depth analysis and guidance in the clinical diagnosis and treatment, and development of new treatments with clinical applied prospect of burn and trauma associated lung injury. It includes study on the pathological change of burn and trauma associated lung injury such as inhalation injury, lung blast injury, pulmonary barotrauma, delayed hemopneumothorax, lung injury associated sepsis, ventilator-induced lung injury and ischemia-reperfusion lung injury. It is also compiled with many clinical typical cases, full data and series of pictures. It also aims at bringing more clinicians’ attention to burn-/trauma-induced lung injury, making them familiar with the relevant theories and clinical diagnose; guiding the treatment of burn and trauma associated lung injury and improving the prognosis and life quality of patients; stimulating more clinicians and researchers to further explore the pathological mechanism and new treatments of burn and trauma associated lung injury. It persists in combining theory and practice, and highlights practical application to reflect the theoretical value. It is very suitable for the medical teaching and can also be used as a reference book for medical doctoral students, postgraduates, and medical trainees receiving continuing education from critical care medicine, burn & trauma surgery, and emergency medicine.
Author: Lynn M. Schnapp
Author: Lynn M. Schnapp
Author: Geoffrey J. Bellingan
Author: Didier Dreyfuss
Author: Sadis Matalon
Author: Ronald G. Crystal
Author: Robert H. Notter
Author: Michael Kasper
Author: Margaux Conference on Critical Illness. 4, 2002, Sintra
Author: Venkataramana K Sidhaye
Author: Zhao-fan Xia