Biologics in Orthopaedic Surgery PDF Download

Author: Augustus D Mazzocca
Publisher: Elsevier Health Sciences
ISBN: 0323551416
Category : Medical
Languages : en
Pages : 400

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Book Description
Designed with the practicing clinician in mind, Biologics in Orthopaedic Surgery provides a succinct, easy-to-digest overview of the integration of biologics (platelet-rich-plasma [PRP], bone marrow aspirate [BMA], and stem cells) into today’s orthopaedic practice. Covering relevant basic science as well as clinical applications, this concise reference takes a head-to-toe approach to the emerging role of orthobiologics for specific conditions and procedures, in addition to future directions for implementation.

Author: James L. Cook
Publisher: Thieme
ISBN: 1626232016
Category : Medical
Languages : en
Pages : 296

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Book Description
Biologics in Orthopaedic Surgery is a clinical reference that provides readers with a thorough review of state-of-the-art orthobiologics currently used by orthopaedic surgeons, including cutting edge developments in this field. Chapters are written by world-renowned experts and cover the relevant science, regulatory aspects, and practical application recommendations for orthobiologics. Key Features: Includes practical application boxes in every chapter that explain how to apply evidence to practice Covers the latest regulatory positions of the Federal Drug Administration (FDA) and the European Medicines Agency (EMA) on the use of biologics for treating musculoskeletal disorders Focuses on contemporary applications and outcomes for biologics used to treat articular cartilage, tendon, ligament, meniscus, and bone injuries/conditions This book is an invaluable reference that helps orthopaedic surgeons properly use currently available biologics for treating orthopaedic disorders.

Author: Giuseppe Filardo
Publisher: Springer Nature
ISBN: 3030847446
Category : Medical
Languages : en
Pages : 394

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Book Description
This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.

Author: Chad Lavender
Publisher: Springer Nature
ISBN: 3030713237
Category : Medical
Languages : en
Pages : 176

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Book Description
In recent years, there have been a number of exciting advances in biologic and nanoarthroscopic approaches in sports medicine, giving the clinician even more options for safe and effective minimally invasive treatments for the active patient. This practical text presents these breakthrough techniques in detail and describes the authors' experiences and lessons learned. This book is broken into two main sections. The first section presents the history of the use of biologics in sports medicine and will have several chapters describing novel techniques using platelet-rich plasma (PRP) and bone marrow concentrate (BMC), all-inside allograft ACL reconstruction, minimally invasive quad tendon harvest with endoscopic closure, and cartilage transfer (ACT) using an autologous tissue collector, among others. The second section describes the history of arthroscopy and the most recent use of nanoarthroscopy, including several novel techniques utilizing the nanoscope, such as incisionless partial medial meniscectomy, synovectomy of the knee, and single incision approaches for the anterior labrum and rotator cuff. Practical and cutting edge, Biologic and Nanoarthroscopic Approaches in Sports Medicine is an exciting exploration of the most recent management approaches for both sports medicine and orthopedic surgeons.

Author: Adam Landsman
Publisher: Elsevier Health Sciences
ISBN: 0323612903
Category : Medical
Languages : en
Pages :

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Book Description
This issue of Clinics in Podiatric Medicine and Surgery, guest edited by Dr. Adam Landsman, will cover a number of topics surrounding the use of Biologics in Foot and Ankle Surgery. Article content includes, but is not limited to: Use of decellularized collagen for resurfacing of the 1st Metatarsal head; Living cryopreserved bone allograft as an adjunct for hindfoot arthrodesis; Synthetic polycaprolactone grafts as an alternative to decellularized collagen for reinforcement of Achilles and posterior tibial tendons; Cartilage substitutes; allograft, acellular and cellular options for osteochondral defects; Cryopreserved living umbilical cord graft for repair of tendon ruptures; Update on the use of decellularized collagen for surgical repair of tendons; The role of amniotic tissue in the prevention of tendon adhesions during surgical repair; and Stem cells can be used to reduce joint pain in the foot and ankle.

Author: Frederick M Azar
Publisher: Elsevier Health Sciences
ISBN: 0323531431
Category : Medical
Languages : en
Pages :

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Book Description
This issue of Orthopedic Clinics focuses on Orthobiologics. Article topics include: Does Prior Cartilage Restoration Impact Outcomes Following Knee Arthroplasty?; Clinical Applications of Tissue Engineering in Joint Arthroplasty: Current Concepts Update; Usage of Bone Graft Substitutes; Bone morphogenetic protein; Role of Bone Marrow Aspirate in Orthopaedic Trauma; Orthobiologics in Pediatric Sports Medicine, and more!

Author: Brian Cole
Publisher: CRC Press
ISBN: 1040136265
Category : Medical
Languages : en
Pages : 591

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Book Description
Treatment of articular cartilage pathology in the knees of young and active patients is a challenging and controversial issue. Biologic Knee Reconstruction: A Surgeon's Guide is a how-to, step-by-step guide that addresses the evaluation and management of this unique patient population. Internationally renowned cartilage experts Dr. Brian J. Cole and Dr. Joshua D. Harris, along with their contributors, present information on normal and abnormal history and physical examination. The reader will learn proper decision-making using a patient-centered approach of treatment, increasing the likelihood of a successful outcome. In addition to radiographic assessment of articular cartilage, Biologic Knee Reconstruction discusses the use of biomarkers, defect classification, and patient-reported and surgeon-measured outcomes. Aggressive nonsurgical medical management, including medications, injections, physiotherapy, and rehabilitation, is also presented. Biologic Knee Reconstruction also discusses the management of concomitant pathologies such as malalignment, meniscal deficiency, and ligamentous instability. Selection of surgical cartilage restorative treatment options is multifactorial, requiring consideration of several patient-, knee-, and defect-specific issues. All contemporary open and arthroscopic cartilage techniques are presented in detail with high resolution figures. A unique feature of Biologic Knee Reconstruction is the presentation of several chapters discussing non-medical issues highly pertinent to the advancement and future of this field: funding of research and cost of new advanced technologies, regulation of advanced cellular, tissue, and genetic technologies, evidence-based medicine and clinical trial design and conduct, and the ethics of allograft tissues and stem cell use. Features: Technique preference cards from the experts performing cartilage surgery Patient education information The most up-to-date descriptions of advanced cartilage techniques Unique chapters not covered in books elsewhere, including: Biomarkers Patient-reported outcomes assessment Newer injection techniques (PRP, stem cells) One- and two-stage open and arthroscopic techniques using chondrocyte- and stem cell based cell therapies Costs and public and private funding of research Barriers to high-quality randomized trials Governmental regulation and availability/accessibility to patients Gene therapy and tissue engineering Ethics of articular cartilage surgery with stem cells, ex-vivo cell manipulation, and juvenile tissue sources With the most up-to-date content and step-by-step methods for surgical procedures, Biologic Knee Reconstruction: A Surgeon's Guide is the perfect addition to the bookshelf of the orthopedic surgeon, cartilage researcher, sports physical therapist, or athletic trainer who evaluates and manages this unique patient population.

Author: Scott P Bruder
Publisher: Lippincott Williams & Wilkins
ISBN: 1975175476
Category : Medical
Languages : en
Pages : 720

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Book Description
Developed in partnership with the American Academy of Orthopaedic Surgeons (AAOS) and edited by internationally renowned experts Drs. Scott P. Bruder and Roy K. Aaron, Orthobiologics: Scientific and Clinical Solutions for Orthopaedic Surgeons provides authoritative, comprehensive coverage of this fast-growing field. This one-stop reference is an ideal resource, covering technology and basic science through specific clinical applications.

Author: Rachel M. Frank
Publisher: Academic Press
ISBN: 0128229039
Category : Science
Languages : en
Pages : 0

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Book Description
OrthoBiologics provides state-of-the-art knowledge of current stem cell therapies for osteoarthritis in a single source. Current literature is dated or spread across many research articles. The coverage is presented in a straightforward manner including: a historical overview, frequently used terminology, processing characteristics, outcomes of different approaches and finally current applications.In addition to covering current approaches and applications, the authors aim for this book to present ‘best practices’ for those practicing and researching osteoarthritis and stem cell treatments in this field. The authors are world-renown experts in the field and this book fills a gap in the market. Presents the current state-of-the-art treatments Includes historical review, terminology overview, processing characteristics, clinical outcomes and more Written for academic researchers, to PhD students, medical doctors, including rheumatologists and orthopaedic surgeons, other physicians and nurses

Author: Julie Balch Samora
Publisher: Springer Nature
ISBN: 3031071050
Category : Medical
Languages : en
Pages : 341

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Book Description
This practical, unique textbook provides a foundation for the essential elements of patient safety and quality improvement (QI) for orthopaedic trainees, though the content covered will be of interest to veteran clinicians as well. Currently, there are few existing resources and didactics focused on this crucial yet often overlooked area of medical practice, which makes this the first true textbook on the subject within the field of orthopaedic surgery. Utilizing a user-friendly approach including generous figures, tables, and bulleted key points, the text presents comprehensive background information on QI principles, models, and patient safety. More specifically, it focuses on orthopaedic concerns, such as biologics and implants, registries, checklists, surgical site infection risk reduction, use of evidence-based medicine and care maps, simulation to improve care, and shifting from volume to value, among others. Related topics such as diversity and inclusion, provider wellness strategies, leadership strategies to develop an efficient and safe work culture, and innovation are also presented. Throughout, the aim is to demonstrate that QI is a multidisciplinary goal that can only flourish in an environment of supportive accountability. With contributions by leaders in the field, Quality Improvement and Patient Safety in Orthopaedic Surgery provides trainees and surgeons in the field a valuable and pragmatic toolkit for successful and sustainable clinical practice.