Fundamentals of Inflammation PDF Download

Author: Charles N. Serhan
Publisher: Cambridge University Press
ISBN: 1139936670
Category : Science
Languages : en
Pages : 489

View

Book Description
The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were not initially known to be linked to the inflammatory response, including cardiovascular disease, asthma, arthritis, and cancer. To better manage treatment, diagnosis, and prevention of these wide-ranging diseases, multidisciplinary research efforts are underway in both academic and industry settings. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion. World-class experts from institutions around the world have written chapters for this introductory text. The text is presented as an introductory springboard for graduate students, medical scientists, and researchers from other disciplines wishing to gain an appreciation and working knowledge of current cellular and molecular mechanisms fundamental to inflammation.

Author: Jean-Marc Cavaillon
Publisher: John Wiley & Sons
ISBN: 3527338993
Category : Medical
Languages : en
Pages : 1818

View

Book Description
The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.

Author: Shelly Malone
Publisher: Agustin Publishing
ISBN: 9780692704400
Category :
Languages : en
Pages :

View

Book Description
Chosen by SELF Magazine as one of "7 Fascinating And Illuminating Books That Will Totally Open Your Eyes About Your Health" Both absorbing and revelatory, INFLAMED isn't just a story of healing (of an inflammatory, autoimmune condition). It's a crystal clear guide that cuts through the confusion and contradiction, offering an anti-inflammatory roadmap to reduce pain, calm chronic symptoms, and light a path to glowing, vibrant health. Whether your personal health simply feels slightly off, or you're experiencing a serious chronic illness, conventional care alone may not be getting you the results you want. Are you experiencing issues like fatigue, poor mood, resistant weight loss, aching joints, digestive upset or skin problems? INFLAMED is your concise guide to changing your life by reducing inflammation. A refreshing voice for readers who appreciate Western medicine, but who are searching for treatments that solve the root cause of their conditions - not just address them with a quick, pharmacological fix - Shelly Malone is the discerning expert chronic sufferers have been waiting for. Inside, readers will find: Exactly what inflammation means and how it manifests (including pain, allergies, infertility, depression, obesity and autoimmune conditions) The complete story on gluten, dairy and other food sensitivities The role your genes do and don't play in disease What your digestive tract is trying to tell you Why it's time to trade the calorie and fat gram counting for brand new eating principles Where inflammatory toxins hide (in your food, in your home and on your body) The synergistic connection between stress, sleep and hormones How your past medical history could be contributing to your poor health INFLAMED closes with a customizable, 25-step action plan the meets you where you are and provides over 20 guides from meal/snack ideas to product label guides to "lesser evils," a chart of delicious (and realistic) food substitutions. Lifestyle change can be intimidating. Learn how to get started with small, specific action steps for consistent progress - and better health. Find a reason - and a way - to live a healthy, vibrant life. www.inflamedbook.com

Author: Irfan Rahman
Publisher: Academic Press
ISBN: 0123978076
Category : Technology & Engineering
Languages : en
Pages : 394

View

Book Description
The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. Includes models of aging, including worm, mouse and human Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition Includes suggested nutritional interventions

Author: D. Neil Granger
Publisher: Morgan & Claypool Publishers
ISBN: 1615041656
Category : Medical
Languages : en
Pages : 99

View

Book Description
The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References

Author: Dr. Will Cole
Publisher: Penguin
ISBN: 0735220093
Category : Health & Fitness
Languages : en
Pages : 336

View

Book Description
From the international bestselling author of Ketotarian comes a revolutionary new plan to discover the foods your unique body loves, hates, and needs to feel great. In Dr. Will Cole's game-changing new book, readers will discover how inflammation is at the core of most common health woes. What's more, it exists on a continuum: from mild symptoms such as weight gain and fatigue on one end, to hormone imbalance and autoimmune conditions on the other. How you feel is being influenced by every meal. Every food you eat is either feeding inflammation or fighting it. Because no one else is you, the foods that work well for someone else may not be right for your body. At heart, The Inflammation Spectrum is about learning to love your body enough to nourish it with delicious, healing foods. You'll find insightful quizzes and empowering advice to put you on a path toward food freedom and overall healing, once and for all.

Author: Masayuki Miyasaka
Publisher: Springer
ISBN: 4431560688
Category : Medical
Languages : en
Pages : 702

View

Book Description
This book provides readers with the most up-to-date information on cutting-edge research concerning chronic inflammation. We now know that when inflammation becomes chronic, it acts as a strong disease-promoting factor in a variety of disorders including arteriosclerosis, obesity, cancer, and Alzheimer disease. Chronic inflammation is hence called as the “silent killer”; it upsets the body’s homeostatic mechanism insidiously. In spite of these developments, we know very little about the mechanism underlying chronic inflammation. Particularly, we do not know precisely what induces chronic inflammation or what promotes its prolongation in a spatiotemporal framework. Neither do we have clear knowledge about how chronic inflammation destroys various tissues or how it predisposes individuals to many different diseases. To make the situation worse, we have no effective treatment against chronic inflammation. Since 2010, two major research programs (CREST and PRESTO) aimed at clarifying the mechanisms underlying chronic inflammation were launched in Japan, and investigators of different research areas with a brilliant track record were selected by their research proposals. Subsequently they have made their best efforts to answer the conundrum concerning chronic inflammation. This book is a compendium of such research efforts. In each chapter, the CREST- or PRESTO-funded researchers summarize their original work concerning mechanisms of induction, progression, or resolution underlying chronic inflammation. The most emphasized characteristic is the molecular aspect of chronic inflammation. The book thus presents the most recent progress made in the molecular understanding of chronic inflammation.

Author: Shampa Chatterjee
Publisher: Academic Press
ISBN: 0128054026
Category : Medical
Languages : en
Pages : 476

View

Book Description
Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here. Conceptualizes the key features in natural products which can boost immune function and immune health Explains the intricate mechanistic aspects and balance behind immune health Presents the pathophysiology of several diseases associated with immune system disruption

Author: Julie Daniluk, RHN
Publisher: Hay House, Inc
ISBN: 1401940358
Category : Cooking
Languages : en
Pages : 418

View

Book Description
Did you know that virtually every health condition from asthma to irritable bowel syndrome is linked to inflammation? When inflammation gets out of control, the result is pain and discomfort—and it’s a phenomenon that’s on the rise. If you’re one of the millions of people who have been affected by allergies, diabetes, skin disorders, heart disease, arthritis, or any other condition ending in "-itis," then you know firsthand what havoc inflammation can cause. In Meals That Heal Inflammation, television personality and registered holistic nutritionist Julie Daniluk shows you how to conquer these health conditions with foods that will make you feel fantastic. This comprehensive book is packed with meals that can assist the body’s healing process—all while treating your taste buds to new and delicious flavors. The recipes, from healing teas to balanced meals and tempting desserts, are simple to make. Whether it’s the savory cranberry quinoa salad or the sumptuous key lime pie, every recipe in this book contains foods that naturally heal inflammation. Extensively researched and full of reference charts, diagnostic quizzes, food comparison lists, and the latest information about the healing properties of everyday foods, Meals That Heal Inflammation is an essential addition to every kitchen.

Author: Richard Fleming
Publisher: Penguin
ISBN: 9781583332009
Category : Health & Fitness
Languages : en
Pages : 324

View

Book Description
An innovative cardiologist reveals the twelve main causes of heart attack and stroke, and presents his breakthrough plan to restore heart health. In this groundbreaking book, nuclear cardiologist and research scientist Dr. Richard M. Fleming exposes the devastating impact of arterial inflammation on the heart and what can be done to douse the fire within. Arterial inflammation triggers a dangerous chain reaction, wreaking havoc throughout the body. Dr. Fleming's action plan explains which tests your doctor should be performing to assess heart disease risk and tells why an angiogram is not always an accurate indicator of heart health. He also reveals a complete picture of the twelve causes of inflammation and how to defeat them. Dr. Fleming's unique two-step program restores balance within the body through simple diet and lifestyle changes that can begin to yield measurable results in as little as two weeks. The plan not only prevents further damage to the heart but can also restore blood flow and reverse heart disease's progress-all without surgery or prescription drug dependence. The book includes detailed menus and more than fifty easy-to-prepare recipes for every meal of the day.