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Author: Yuri Vassilevski Publisher: Academic Press ISBN: 0128156546 Category : Science Languages : en Pages : 282
Book Description
Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences. Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies. Examines a variety of medical disciplines targeted by mathematical modeling and computer simulation Discusses how the results of numerical simulations are used to support clinical decision-making Covers hemodynamics relating to various subject areas, including vascular surgery and oncological tumor treatments
Author: Yuri Vassilevski Publisher: Academic Press ISBN: 0128156546 Category : Science Languages : en Pages : 282
Book Description
Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences. Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies. Examines a variety of medical disciplines targeted by mathematical modeling and computer simulation Discusses how the results of numerical simulations are used to support clinical decision-making Covers hemodynamics relating to various subject areas, including vascular surgery and oncological tumor treatments
Author: Lucian Mihai Itu Publisher: Springer ISBN: 3319568531 Category : Medical Languages : en Pages : 227
Book Description
Hemodynamic computations represent a state-of-the-art approach for patient-specific assessment of cardiovascular pathologies. The book presents the development of reduced-order multiscale hemodynamic models for coronary artery disease, aortic coarctation and whole body circulation, which can be applied in routine clinical settings for personalized diagnosis. Specific parameter estimation frameworks are introduced for calibrating the parameters of the models and high performance computing solutions are employed to reduce their execution time. The personalized computational models are validated against patient-specific measurements. The book is written for scientists in the field of biomedical engineering focusing on the cardiovascular system, as well as for research-oriented physicians in cardiology and industrial players in the field of healthcare technologies.
Author: Roy C.P. Kerckhoffs Publisher: Springer Science & Business Media ISBN: 1441966919 Category : Science Languages : en Pages : 240
Book Description
Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial pressure and flow distributions. Thrombus formation is identified as a potentially important contributor to changed material properties of the arterial wall. Understanding how the wall adapts and remodels its material properties in the face of changes in both the stress loading and blood constituents associated with infl- matory processes (IL6, CRP, MMPs, etc.
Author: Jiyuan Tu Publisher: Springer ISBN: 9401795940 Category : Technology & Engineering Languages : en Pages : 351
Book Description
This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book’s approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.
Author: Jiyuan Tu Publisher: ISBN: 9789492497420 Category : Biomedical engineering Languages : en Pages : 0
Book Description
This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book?s approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.
Author: Matteo Anselmino Publisher: Frontiers Media SA ISBN: 2832538762 Category : Medical Languages : en Pages : 169
Book Description
This Research Topic is part of the Insights in Frontiers in Cardiovascular Medicine series. Following the success of the inaugural series, Frontiers has organized a series of Research Topics to highlight the latest advancements in research across the field of cardiovascular medicine, with articles from the members of our accomplished Editorial Boards. This editorial initiative of particular relevance, led by Professor Matteo Anselmino, Specialty Chief Editor of the Cardiac Rhythmology section, together with Dr. Hung-Fat Tse, is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of cardiac rhythmology. The Research Topic solicits brief, forward-looking contributions from the editorial board members that describe the state of the art, outlining recent developments and major accomplishments that have been achieved and that need to occur to move the field forward. Authors are encouraged to identify the greatest challenges in the sub-disciplines, and how to address those challenges.
Author: Vitaly Volpert Publisher: MDPI ISBN: 3039434934 Category : Mathematics Languages : en Pages : 224
Book Description
Mathematical modelling in biomedicine is a rapidly developing scientific discipline at the intersection of medicine, biology, mathematics, physics, and computer science. Its progress is stimulated by fundamental scientific questions and by the applications to public health. This book represents a collection of papers devoted to mathematical modelling of various physiological problems in normal and pathological conditions. It covers a broad range of topics including cardiovascular system and diseases, heart and brain modelling, tumor growth, viral infections, and immune response. Computational models of blood circulation are used to study the influence of heart arrhythmias on coronary blood flow and on operating modes for left-ventricle-assisted devices. Wave propagation in the cardiac tissue is investigated in order to show the influence of tissue heterogeneity and fibrosis. The models of tumor growth are used to determine optimal protocols of antiangiogenic and radiotherapy. The models of viral hepatitis kinetics are considered for the parameter identification, and the evolution of viral quasi-species is investigated. The book presents the state-of-the-art in mathematical modelling in biomedicine and opens new perspectives in this passionate field of research.
Author: Margarita N. Favorskaya Publisher: Springer Nature ISBN: 9813347090 Category : Technology & Engineering Languages : en Pages : 302
Book Description
This book is a collection of research papers selected for presentation at the International Conference on Smart Computational Methods in Continuum Mechanics 2021, organized by Moscow Institute of Physics and Technology and the Institute for Computer Aided Design of Russian Academy of Sciences. The work is presented in two volumes. The primary objective of the book is to report the state-of-the-art on smart computational paradigms in continuum mechanics and explore the use of artificial intelligence paradigms such as neural nets, and machine learning for improving the performance of the designed engineering systems. The book includes up-to-date smart computational methods which are used to solve problems in continuum mechanics, engineering, seismic prospecting, non-destructive testing, and so on. The main features of the book are the research papers on the application of novel smart methods including neural nets and machine learning, computational algorithms, smart software systems, and high-performance computer systems for solving complex engineering problems. The case studies pertaining to the real-world applications in the above fields are included. The book presents a collection of best research papers in English language from some of the world leaders in the field of smart system modelling and design of engineering systems.
Author: Kevin Daimi Publisher: Springer Nature ISBN: 3031421124 Category : Technology & Engineering Languages : en Pages : 379
Book Description
This book is comprehensive with most of its contents following the recommendations of international health and medical informatics associations and societies. To this extent it covers the areas of healthcare and medical information systems, management of healthcare and medical information systems, healthcare/medical information systems supporting patients and the public, healthcare/medical networking and care sharing, medical imaging and 3D/4D surgical visualization, design and analysis of health/medical records, health/medical data representation and analysis, simulation and modeling in healthcare, and health and medical informatics education. The book provides an excellent professional development resource for educators and practitioners on the state-of-the-art Health and Medical Informatics. It covers many areas and topics of Health and Medical Informatics and contributes toward the enhancement of the community outreach and engagement component of Health and Medical Informatics. Various techniques, methods, and approaches adopted by Health and Medical Informatics experts in the field are introduced. Furthermore, it provides detailed explanation of the Health and Medical Informatics concepts that are aptly reinforced by applications and some practical examples and a road map of future trends that are suitable for innovative Health and Medical Informatics.
Author: Yuri Vassilevski
Author: Yuri Vassilevski
Author: Lucian Mihai Itu
Author: Selene Pirola
Author: Roy C.P. Kerckhoffs
Author: Jiyuan Tu
Author: Jiyuan Tu
Author: Matteo Anselmino
Author: Vitaly Volpert
Author: Margarita N. Favorskaya
Author: Kevin Daimi