The Hippocampus in Clinical Neuroscience PDF Download

Author: K. Szabo
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318025682
Category : Medical
Languages : en
Pages : 174

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Book Description
The hippocampus is one of the most intriguing structures of the human brain. Damage to this part causes symptoms ranging from transient disorders accompanied by tiny lesions to severely debilitating cognitive disorders with marked tissue loss. This publication provides a predominantly clinical approach to the complex workings of the hippocampus from different perspectives, ranging from basic principles to specific diseases. The first part of the book summarizes current knowledge regarding the structure and physiology of the hippocampus and establishes the ties to basic neuroscience. The second part deals with the function and assessment of the human hippocampus, including memory function, neuropsychological measures, and conventional and functional imaging studies. The chapters of the third part are devoted to the hippocampus in neurological disorders, e.g. the interaction between stress and memory function, and the pathological conditions of common as well as selected rare neurological diseases affecting the hippocampus. The book is highly recommended to clinical neurologists who wish to gain a broad understanding of this complex and fascinating organ in terms of basic principles, modern imaging findings, and specific diseases.

Author: Thorsten Bartsch
Publisher: Oxford University Press
ISBN: 0191628956
Category : Medical
Languages : en
Pages : 336

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Book Description
The hippocampus is one of the most studied structures in the human brain and plays a pivotal role in human memory function. Its recognized function is reflected by the presence of an extensive body of neurophysiological, neuropsychological, anatomical and neurocomputational literature that presents basic mechanisms, theoretical models and psychological concepts. However, in the rapidly growing field of hippocampal research, the clinical aspects of diseases that affect the hippocampus are greatly under-represented in current literature, and clinical approaches and concepts are scattered throughout various clinical and basic scientific disciplines. The Clinical Neurobiology of the Hippocampus explores clinical approaches to the range of diseases that affect the hippocampus. It brings together and reviews the common methods, clinical findings, concepts, mechanisms and, where applicable, therapeutic strategies for these clinical approaches. The clinical spectrum of hippocampal dysfunction encompasses a wide range of neurological, behavioural and psychiatric symptoms and surpasses the ability to encode, store and retrieve information. The relevance of hippocampal involvement in clinical diseases goes beyond mere neuropsychological deficits and includes psychopathological states in various conditions, such as acute amnesic syndromes, Alzheimer's disease, temporal lobe epilepsy (TLE), sleep, stroke medicine, limbic encephalitis, neurodevelopmental disorders, stress- and trauma-related disorders, depression, and schizophrenia. The first part of the book covers the basic and integrative features of the hippocampus, such as the anatomy and imaging of this structure, and the basic mechanisms of hippocampal function, including the principles of hippocampus-dependent memory processing in amnesia and sleep, the mechanisms of vulnerability and adult neurogenesis as well as the effects of stress. The second part covers the various clinical manifestations in which the hippocampus is involved and in which the preceding basic mechanisms are reflected. Bringing together a broad team of experts on the basic and clinical aspects of the hippocampus, the book provides an integrative view of the hippocampus. It is invaluable for neurologists, neuroscientists, and psychiatrists, and will stimulate interdisciplinary discussions in clinical neuroscience.

Author: Kelly Lambert
Publisher: Macmillan
ISBN: 9780716752271
Category : Psychology
Languages : en
Pages : 666

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Book Description
Integrating neurobiological mechanisms of general health into the coverage of mental disorders, this text also looks at other aspects of neuroscience and the ways in which it impacts on the mental condition.

Author: Charles Zorumski
Publisher: Oxford University Press
ISBN: 0199768765
Category : Medical
Languages : en
Pages : 322

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Book Description
Research in neuroscience is revolutionizing how we think about psychiatric diagnosis and treatment. Psychiatric disorders reflect dysfunction of the human mind and involve changes in cognition, emotion, and motivation. Understanding how the neural networks that underlie these mental functions become dysfunctional holds great promise for devising innovative approaches to diagnosis and treatment. Scientific progress is being driven, in part, by advances in human functional neuroimaging, which is being used to characterize the activity of specific brain circuits at rest and during the performance of specific tasks. Moreover, advances in clinical neuroscience are being coupled with expanding knowledge about genetics and cellular and synaptic neuroscience. Taken together, these advancements offer the hope of much more mechanism-based approaches to treatment in the future. Better understanding of neural circuits also can provide the basis for innovative psychotherapeutic strategies that take advantage of brain plasticity for purposes of neurorehabilitation. In this book, we examine recent developments in the field of network neuroscience and their potential impact on clinical psychiatry, including the way that psychiatrists are trained and interact with other medical specialties and mental health professionals.

Author: Deborah E. Hannula
Publisher: Springer
ISBN: 3319504061
Category : Medical
Languages : en
Pages : 589

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Book Description
The hippocampus has long been considered a critical substrate in the neurobiology, neuropsychology, and cognitive neuroscience of memory. Over the past few decades, a number of ground-breaking theoretical and methodological advances have radically enhanced our understanding of the structure and function of the hippocampus and revolutionized the neuroscientific study of memory. Cutting across disciplines and approaches, these advances offer novel insights into the molecular and cellular structure and physiology of the hippocampus, the role of hippocampus in the formation, (re)consolidation, enhancement, and retrieval of memory across time and development, and permit investigators to address questions about how the hippocampus interacts, functionally and anatomically, with other neural systems in service of memory. In addition, recent investigations also suggest that the mechanistic properties and functional processing features of the hippocampus permit broader contributions to cognition, beyond memory, to the domains of attention, decision-making, language, social cognition, and a variety of other capacities that are critical for flexible cognition and behavior. These advances have profound implications for the neurobiology and cognitive neuroscience of hippocampus dependent cognition and for the numerous psychiatric and neurological diseases and disorders for which hippocampal pathology is a hallmark such as Alzheimer’s disease and schizophrenia. The goal of this book is to bring together in a single source an integrated review of these advances providing state of the art treatment on the structure and function of the hippocampus. Contributors will examine the hippocampus from a variety of levels (from cells to systems) using a wide range of methods (from neurobiological approaches in non-human animals to neuroimaging and neuropsychological work in humans).

Author: Paul A. Young
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781753197
Category : Medical
Languages : en
Pages : 422

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Book Description
Basic Clinical Neuroscience offers medical and other health professions students a clinically oriented description of human neuroanatomy and neurophysiology. This text provides the anatomic and pathophysiologic basis for understanding neurologic abnormalities through concise descriptions of functional systems with an emphasis on medically important structures and clinically important pathways. It emphasizes the localization of specific anatomic structures and pathways with neurological deficits, using anatomy enhancing 3-D illustrations. Basic Clinical Neuroscience also includes boxed clinical information throughout the text, a key term glossary section, and review questions at the end of each chapter, making this book comprehensive enough to be an excellent Board Exam preparation resource in addition to a great professional training textbook. The fully searchable text will be available online at thePoint.

Author: Robert Isaacson
Publisher: Springer Science & Business Media
ISBN: 1468429795
Category : Medical
Languages : en
Pages : 451

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Book Description
These books are the result of a conviction held by the editors, authors, and publisher that the time is appropriate for assembling in one place information about functions of the hippocampus derived from many varied lines of research. Because of the explosion of research into the anatomy, physiology, chemistry, and behavioral aspects of the hip pocampus, some means of synthesis of the results from these lines of research was called for. We first thought of a conference. In fact, officials in the National Institute of Mental Health suggested we organize such a conference on the hippocampus, but after a few tentative steps in this direction, interest at the federal level waned, probably due to the decreases in federal support for research in the basic health sciences so keenly felt in recent years. However, the editors also had come to the view that conferences are mainly valuable to the participants. The broad range of students (of all ages) of brain behavior relations do not profit from conference proceedings unless the proceedings are subsequently published. Furthermore, conferences dealing with the functional character of organ systems approached from many points of view are most successful after participants have become acquainted with each other's work. Therefore, we believe that a book is the best format for disseminating information, and that its publication can be the stimulus for many future conferences.

Author: Robert Isaacson
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 448

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Book Description
These books are the result of a conviction held by the editors, authors, and publisher that the time is appropriate for assembling in one place information about functions of the hippocampus derived from many varied lines of research. Because of the explosion of research into the anatomy, physiology, chemistry, and behavioral aspects of the hip pocampus, some means of synthesis of the results from these lines of research was called for. We first thought of a conference. In fact, officials in the National Institute of Mental Health suggested we organize such a conference on the hippocampus, but after a few tentative steps in this direction, interest at the federallevel waned, probably due to the decreases in federal support for research in the basic health sciences so keenly feit in recent years. However, the editors also had co me to the view that conferences are mainly valuabIe to the participants. The broad range of students (of all ages) of brain behavior relations do not profit from conference proceedings unless the proceedings are subsequently published. Furthermore, conferences dealing with the functional character of organ systems approached from many points of view are most successful after participants have become acquainted with each other's work. Therefore, we believe that a book is the best format for disseminating information, and that its publication can be the stimulus for many future conferences.

Author: Ronald A. Cohen
Publisher: Springer Science & Business Media
ISBN: 1441963731
Category : Psychology
Languages : en
Pages : 404

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Book Description
Rapid developments in brain neuroimaging methods have occurred over the past decade. These advances have revolutionized cognitive and behavioral neuroscience, and are likely to have major influence on clinical psychological, psychiatric, and neurological practice over the coming years. There are a number of excellent books that focus on specific neuroimaging methods, such as fMRI. Furthermore, cognitive and neuroscience texts have increasingly incorporated functional brain neuroimaging. Yet, there are few books to date that consider and review emerging research in the application of brain neuroimaging methods for the study and assessment of behavioral and cognitive disorders. This book provides a broad coverage of current research trends in the clinical application of brain neuroimaging methods in the context of behavioral medicine, neuropsychology, and related areas of medical psychology. It uniquely integrates current neuroimaging methods and studies with current behavioral medicine research, and presents knowledge derived from recent developments in the fields of functional and structural brain imaging. By integrating information from experimental behavioral medicine with clinical insights, this book will serve as a source book for neuropsychologists, psychologists, neurologists, psychiatrists, and other professionals in both clinical practice and academic context. This integration results in the reader having a greater understanding of how the brain controls behavior, the disturbances of behavior that may occur with different disorders, and what clinicians should consider when assessing or working with patients with behavioral problems.

Author: Maria A. Ron
Publisher: Cambridge University Press
ISBN: 9780521004565
Category : Medical
Languages : en
Pages : 504

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Book Description
This authoritative new book details the most recent advances in clinical neuroscience, from neurogenetics to the study of consciousness.