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The Microbiome in Rheumatic Diseases and Infection

The Microbiome in Rheumatic Diseases and Infection PDF Author: Gaafar Ragab
Publisher: Springer
ISBN: 3319790269
Category : Medical
Languages : en
Pages : 490

Book Description
This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms in autoimmunity and the deeply related rheumatic diseases. This book comprehensively explains the emerging microbiome research through the interrelationships of biomedical sciences, including: immunology, microbiology, bioinformatics, and, with special emphasis, the clinical aspect of rheumatology. It examines the interplay between infectious organisms and major autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, juvenile arthritis, systemic lupus erythematosus, and vasculitis, and explains how to apply that knowledge to diagnostic techniques and treatment decisions. The international team of expert authors provides insight into current therapies and future interventions specifically targeting the microbiota and explores the impact of our deeper understanding on enhancing personalized medicine. The Microbiome in Rheumatic Diseases and Infection is an essential resource for rheumatologists, pediatricians, internists, microbiologists, and critical care providers caring for children and adults with rheumatic diseases.

The Microbiome in Rheumatic Diseases and Infection

The Microbiome in Rheumatic Diseases and Infection PDF Author: Gaafar Ragab
Publisher: Springer
ISBN: 3319790269
Category : Medical
Languages : en
Pages : 490

Book Description
This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms in autoimmunity and the deeply related rheumatic diseases. This book comprehensively explains the emerging microbiome research through the interrelationships of biomedical sciences, including: immunology, microbiology, bioinformatics, and, with special emphasis, the clinical aspect of rheumatology. It examines the interplay between infectious organisms and major autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, juvenile arthritis, systemic lupus erythematosus, and vasculitis, and explains how to apply that knowledge to diagnostic techniques and treatment decisions. The international team of expert authors provides insight into current therapies and future interventions specifically targeting the microbiota and explores the impact of our deeper understanding on enhancing personalized medicine. The Microbiome in Rheumatic Diseases and Infection is an essential resource for rheumatologists, pediatricians, internists, microbiologists, and critical care providers caring for children and adults with rheumatic diseases.

Infections and the Rheumatic Diseases

Infections and the Rheumatic Diseases PDF Author: Luis R. Espinoza
Publisher: Springer Nature
ISBN: 3030233111
Category : Medical
Languages : en
Pages : 460

Book Description
This book provides a comprehensive and up-to-date review of the basic and clinical aspects of infections and infectious processes that trigger or aggravate a variety of autoimmune and inflammatory musculoskeletal disorders. It delivers a timely update on the interactions between infection and rheumatic diseases in order to provide clinicians with the tools they need for proper diagnosis and treatment. The book is divided into five main sections. The first examines the basic aspects of bacterial infections with a discussion of molecular biology, the microbiome, various types of bacteria that cause infection, and recent advances in biologic therapy. The next section focuses on different forms of viral arthritis including hepatitis arthritis, arthritis associated with alpha viruses, and parvovirus-related arthritis. Subsequent chapters then discuss arthritis caused by mycobacteria, fungi, spirochete, and other miscellaneous arthritides. Following this are various analyzations on reactive arthritis and infection-related rheumatic diseases such as Whipple’s Disease, SAPHO Syndrome, rheumatic fever, and HIV-associated rheumatic manifestations. Finally, the book closes with three chapters on external impacts on infectious diseases such as climate change, vaccinations and systemic lupus erythematosus. Infections and the Rheumatic Diseases is an essential resource for physicians and related professionals, residents, fellows, graduate students, and nurses in rheumatology, clinical immunology, and internal medicine.

Applications of Next Generation Sequencing (NGS) Technologies to Decipher the Oral Microbiome in Systemic Health and Disease

Applications of Next Generation Sequencing (NGS) Technologies to Decipher the Oral Microbiome in Systemic Health and Disease PDF Author: Thuy Do
Publisher: Frontiers Media SA
ISBN: 288974308X
Category : Science
Languages : en
Pages : 223

Book Description


The Autoimmune Brain

The Autoimmune Brain PDF Author: David S. Younger
Publisher: Rowman & Littlefield
ISBN: 1538117711
Category : Health & Fitness
Languages : en
Pages : 289

Book Description
There are millions of people who experience issues related to brain health—depression, attention issues, anxiety, forgetfulness, fatigue, and even chronic pain—yet can’t figure out what’s causing their problems and can’t find any relief. They may have seen a myriad of doctors, many of whom do not take their complaints seriously, or worse, turn to the easy, often inappropriate fix of antidepressants or anti-anxiety medications. Traditional medications, supplements, or other therapies haven’t worked. No matter what their age—from children to teens or seniors—people and their loved ones are frustrated, scared, and confused by their continued poor health. Countless others display severe psychiatric symptoms that seem to come out of nowhere, ranging from tics, obsessive-compulsive behaviors and anxiety, to depression, bipolar-like mood swings, and even borderline personality disorder and suicidal ideas. Sometimes, the people affected are the only ones that notices a change to the way they think or feel, and they suffer in silence. Or, they reach out to try to get help, and are all too frequently misdiagnosed. David Younger, a world-renowned physician, provides relief to these patients and their families. His diagnostic techniques and treatment protocols will help readers identify the true cause of their symptoms and put them on a clear path to healing so they no longer feel unbalanced, out of control, forgetful, and exhausted. The Autoimmune Brain connects common brain health symptoms to the changes in the immune system, and particularly bacterial, viral, and parasitic infections. Younger explains his groundbreaking research and adds a new component: how traumatic stress (whether physical or emotional) and genetics affects this same triad as inextricable factors in initiating disease and brain health symptoms. In fact, a change in personality, behavior, coping style, and one’s emotional state may be the first clue that there is a health problem brewing somewhere else in the body. Readers will find new answers to troubling conditions, including: Alzheimer’s disease; Anxiety; Arthritis; Autism; Autonomic disturbances; Bacterial and viral infections; Bipolar Disorder; Cancer; Celiac disease and gluten intolerances; Chronic Fatigue Syndrome (now referred to as Systemic Exertion Intolerance Disease); Chronic Pain; Dementia; Depression; Endocrine Disorders; Immune modulatory therapy using IVIg; Lyme disease and co-infections; Mast cell activation syndrome; Medical cannabis; Obsessive Compulsive Disorder; Orthostatic hypotension; Peripheral Neuropathy; Porphyria; Post-Traumatic Stress Disorder; and Postural orthostatic tachycardia.

Idiotypes in Medicine: Autoimmunity, Infection and Cancer

Idiotypes in Medicine: Autoimmunity, Infection and Cancer PDF Author: R.C. Kennedy
Publisher: Elsevier
ISBN: 9780080534435
Category : Medical
Languages : en
Pages : 540

Book Description
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

Metagenomics of the Human Body

Metagenomics of the Human Body PDF Author: Karen E. Nelson
Publisher: Springer Science & Business Media
ISBN: 1441970894
Category : Science
Languages : en
Pages : 351

Book Description
The book brings a completely different perspective than available books by combining the information gained from the human genome with that derived from parallel metagenomic studies, and new results from investigating the effects of these microbes on the host immune system. Although there are a number of books that focus on the human genome that are currently available, there are no books that bring to the forefront the mix of the human genome and the genomes and metagenomes of the microbial species that live within and on us.

Natural Autoantibodies

Natural Autoantibodies PDF Author: Yehuda Shoenfeld
Publisher: CRC Press
ISBN: 9780849355011
Category : Medical
Languages : en
Pages : 374

Book Description
Natural Autoantibodies provides an in-depth analysis of all aspects of natural antibodies. The book examines the advantages and pitfalls of every type of technique that is widely used for detecting autoantibodies. It also covers the sequencing of human autoantibody genes, discussing how sequencing is undertaken and the genetic clues available to elucidate the genetic origins of autoimmunity. Animal models of autoimmunity are also covered, and the up-to-date account provided in this book explains how natural autoantibodies have important regulatory functions and also occasionally serve as templates for autoimmunity. Other topics examined in Natural Autoantibodies: Their Physiological Role and Regulatory Significance include idiotypes of natural autoantibodies; the pathogenic role of natural autoantibodies; and methods to measure the effects of genetic and sex hormones, as well as aging, on natural autoantibodies. The book will be an excellent research tool and reference for immunologists, rheumatologists, and others interested in the topic.

A Rational Approach to Clinical Infectious Diseases

A Rational Approach to Clinical Infectious Diseases PDF Author: Zelalem Temesgen
Publisher: Elsevier Health Sciences
ISBN: 0323695795
Category : Medical
Languages : en
Pages : 307

Book Description
Written specifically for non-infectious disease specialists in both inpatient and outpatient settings, A Rational Approach to Clinical Infectious Diseases provides concise, practical guidance that mimics the decision-making process and reasoning employed by an ID physician. Using clear, understandable language, Dr. Zelalem Temesgen and his esteemed colleagues at the Mayo Clinic present the art and the context of infectious diseases together with the science, helping non-specialists apply a rational approach to the diagnosis and treatment of infectious conditions. Clearly explains the rationale of opting for one particular treatment or length of course over another in order to arrange appropriate management and follow-up. Provides focused ID decision support to questions such as: What diagnostic test should I order? What is the correct antibiotic for this patient/geographical region? Are IV or oral antibiotics most appropriate? How long should the antibiotic course be and when should it be de-escalated? What special considerations should be taken in immunocompromised patients? How often should complex infections be followed up? Uses a succinct, easy-to-read writing style, following a consistent format: Important characteristics/epidemiology; Clinical related data; Rash characteristics; Ancillary diagnostic studies; Treatment; and Other. Provides visual and quick-reference support with dozens of figures and tables throughout the text. Contains invaluable guidance to help non-specialists provide the best care for patients, stem antibiotic misuse and resistance, avoid adverse drug events, and avoid unnecessary costs.

Microbiology: A Very Short Introduction

Microbiology: A Very Short Introduction PDF Author: Nicholas P. Money
Publisher: OUP Oxford
ISBN: 0191503916
Category : Science
Languages : en
Pages : 144

Book Description
In recent decades we have come to realize that the microbial world is hugely diverse, and can be found in the most extreme environments. Fungi, single-celled protists, bacteria, archaea, and the vast array of viruses and sub-viral particles far outnumber plants and animals. Microbes, we now know, play a critical role in ecosystems, in the chemistry of atmosphere and oceans, and within our bodies. The field of microbiology, armed with new techniques from molecular biology, is now one of the most vibrant in the life sciences. In this Very Short Introduction Nicholas P. Money explores not only the traditional methods of microscopy and laboratory culture but also the modern techniques of genetic detection and DNA sequencing, genomic analysis, and genetic manipulation. In turn he demonstrates how advances in microbiology have had a tremendous impact on the areas of medicine, agriculture, and biotechnology. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Periodontitis

Periodontitis PDF Author: Pachiappan Arjunan
Publisher: BoD – Books on Demand
ISBN: 9535136054
Category : Medical
Languages : en
Pages : 200

Book Description
Periodontitis - A Useful Reference is a comprehensive book compiled by a team of experts with the objective of providing an overview of the basic pathology of "periodontitis" and its implication on oral health and general systemic health. Periodontitis has become a global health burden in recent days. It is noteworthy that oral health is being considered as the mirror of general health and the study of oral-systemic health connections has advanced among scientists, clinicians, and the public as well. We wish the array of chapters that highlights the importance and impact of periodontal health could be a useful guide for the community of public, students, and clinicians.