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Author: Edward J. Moticka Publisher: Newnes ISBN: 0123983754 Category : Medical Languages : en Pages : 394
Book Description
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells
Author: Edward J. Moticka Publisher: Newnes ISBN: 0123983754 Category : Medical Languages : en Pages : 394
Book Description
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells
Author: W. D. Foster Publisher: Butterworth-Heinemann ISBN: 1483162451 Category : Medical Languages : en Pages : 244
Book Description
A History of Medical Bacteriology and Immunology provides the account of the history of bacteriology from the year 1900 to 1938. This book presents details about the discovery of the important pathogenic bacteria of man, of how they were shown to be causally related to disease, and of the use of these discoveries in the diagnosis, treatment, and prevention of disease. Other topics discussed include the development of the germ theory of infectious diseases; contribution of Louis Pasteur and Robert Koch to medical bacteriology; and discovery of the more important human pathogenic bacteria. This text also discusses the scientific basis and practical application of immunology to medicine; main developments in bacteriology during the early 20th century; and chemotherapy of bacterial disease. This medically oriented text is beneficial for students and individuals conducting study on medical bacteriology and immunology.
Author: Shailza Singh Publisher: Springer Nature ISBN: 9811533504 Category : Medical Languages : en Pages : 273
Book Description
Systems and Synthetic Immunology focuses on the similarities between biology and engineering at the systems level, which are important for applying engineering theories to biology problems. With the advent of new genomic techniques, there are numerous systematic investigations underway in the scientific world. This volume highlights techniques that can be used to effectively combine two of the most essential biological fields - Systems Biology and Synthetic Immunology. The respective chapters discuss the role of synthetic immunology in biotechnology, production of biomaterials, and their use in vaccine delivery. Further topics include the importance of cytokines; the use of genomic engineering tools in immunotherapy; immunosensors; nanotherapeutics; and bioinformatics tools in biomedical applications. Given its scope, the book offers readers an up-to-date and comprehensive review of this unique and dynamic field of research.
Author: Dale A. Stirling Publisher: CRC Press ISBN: 1000574830 Category : Medical Languages : en Pages : 589
Book Description
The COVID-19 pandemic provides stark evidence of the importance of medicine on a global scale. However, revisiting the influenza pandemic of 1918 provided a perspective as we searched for a viable vaccine and instituted public health measures. This shows that medical knowledge is an accumulative process extending to the past and it is in the spirit of that legacy that this bibliography has been compiled. The book is a one-stop resource that cites literature related to the historical aspects of medicine. It also acknowledges medicine’s global reach and devotes significant effort in that respect. Although the online world seems to dominate on both a social and educational level, there is still a need for thoughtfully curated and focused reference works and this bibliography accomplishes that goal. The book has 9,000+ citations. It utilizes the WHO's International classification of Diseases for the section on diseases and disorders and the U.S. Food & Drug Administration's Product Code Classification Database for the section on medical devices, equipment, and instruments. It includes detailed subject, geographuc, and people indexes for an easy reference.
Author: Shilpa Ravella Publisher: W. W. Norton & Company ISBN: 0393541916 Category : Medical Languages : en Pages : 215
Book Description
“Fascinating.…[Ravella’s writing] breathes life into biological functions.” —Grace Wade, New Scientist A riveting investigation of inflammation—the hidden force at the heart of modern disease—and how we can prevent, treat, or even reverse it. Inflammation is the body’s ancestral response to its greatest threats, the first line of defense it deploys against injury and foreign pathogens. But as the threats we face have evolved, new science is uncovering how inflammation may also turn against us, simmering underneath the surface of leading killers from heart disease and cancer to depression, aging, and mysterious autoimmune conditions. In A Silent Fire, gastroenterologist Shilpa Ravella investigates hidden inflammation’s emerging role as a common root of modern disease—and how we can control it. We meet the visionary nineteenth-century pathologist who laid the foundation for our modern understanding of inflammation, the eccentric Russian zoologist who discovered one of the cells central to our immune system, and the dedicated researchers advancing the frontiers of medical and nutritional science today. With fascinating case studies, Ravella reveals how we can reform our relationships with food and our microbiomes to benefit our own health and the planet’s. Synthesizing medical history, cutting-edge research, and innovative clinical practice, Ravella unveils inflammation as one potential basis for a unifying theory of disease. A paradigm-shifting understanding of one of the most mysterious, buzzed-about topics in medicine and nutrition, A Silent Fire shows us how to live not only long but well.
Author: Nima Rezaei Publisher: Academic Press ISBN: 0128140402 Category : Medical Languages : en Pages : 198
Book Description
Therapeutic cancer vaccines represent a type of active cancer immunotherapy. Clinicians, scientists, and researchers working on cancer treatment require evidence-based and up-to-date resources relating to therapeutic cancer vaccines. Vaccines for Cancer Immunotherapy provides a reference for cancer treatment for clinicians and presents a well-organized resource for determining high-potential research areas. The book considers that this promising modality can be made more feasible as a treatment for cancer. Chapters cover cancer immunology, general approaches to cancer immunotherapy, vaccines, tumor antigens, the strategy of allogeneic and autologous cancer vaccines, personalized vaccines, whole-tumor antigen vaccines, protein and peptide vaccines, dendritic cell vaccines, genetic vaccines, candidate cancers for vaccination, obstacles to developing therapeutic cancer vaccines, combination therapy, future perspectives and concluding remarks on therapeutic cancer vaccines. Introduces the feasible immunotherapeutic vaccines for patients with different types of cancer Presents the status of past and current vaccines for cancer treatment Considers advantages and disadvantages of different therapeutic cancer vaccines Looks at the combination of vaccines and other modalities, including immunotherapeutic and conventional methods Analyzes obstacles to development of therapeutic cancer vaccines Gives a view on future perspectives in the application of therapeutic cancer vaccines
Author: Martin Flajnik Publisher: Lippincott Williams & Wilkins ISBN: 1975142527 Category : Medical Languages : en Pages : 3597
Book Description
Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.
Author: Antonio L. Teixeira Publisher: Oxford University Press, USA ISBN: 0190884460 Category : Science Languages : en Pages : 323
Book Description
In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.
Author: Edward J. Moticka
Author: Edward J. Moticka
Author: W. D. Foster
Author: George Rosen
Author: Shailza Singh
Author: Dale A. Stirling
Author: Steven A. Frank
Author: Shilpa Ravella
Author: Nima Rezaei
Author: Martin Flajnik
Author: Antonio L. Teixeira