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Author: Hiroaki Ohya-Nishiguchi Publisher: Springer Science & Business Media ISBN: 9783764350772 Category : Gardening Languages : en Pages : 358
Book Description
This book presents the historical background as well as the up-to-date developments in, and guidelines for, bioradicals and ESR research. Bioradicals Detected by ESR Spectroscopy is a newly coined term which encompasses paramagnetic species in biological systems, such as active oxygen radicals and transition metal ions. Research on the structures and functions of bioradicals have been attracting growing attention in the biological sciences, resulting in an increasing demand for comprehensive studies which allow researchers from many fields to understand the true importance of these species. ESR spectroscopy is of great interest to interdisciplinary research and is applied in many fields, ranging from physics and chemistry to biology and medicine. New ESR technologies of multiquantum ESR, STM-ESR and open-space ESR, several ESR imaging techniques, spin trapping and new methods in in vivo spin trapping are all described and discussed in this volume. In addition, it demonstrates the applications of ESR in food and medical sciences, i.e., the estimation and characterization of the antioxidant ability of foods and food components and the elucidation of the underlying chemical mechanisms.
Author: Hiroaki Ohya-Nishiguchi Publisher: Springer Science & Business Media ISBN: 9783764350772 Category : Gardening Languages : en Pages : 358
Book Description
This book presents the historical background as well as the up-to-date developments in, and guidelines for, bioradicals and ESR research. Bioradicals Detected by ESR Spectroscopy is a newly coined term which encompasses paramagnetic species in biological systems, such as active oxygen radicals and transition metal ions. Research on the structures and functions of bioradicals have been attracting growing attention in the biological sciences, resulting in an increasing demand for comprehensive studies which allow researchers from many fields to understand the true importance of these species. ESR spectroscopy is of great interest to interdisciplinary research and is applied in many fields, ranging from physics and chemistry to biology and medicine. New ESR technologies of multiquantum ESR, STM-ESR and open-space ESR, several ESR imaging techniques, spin trapping and new methods in in vivo spin trapping are all described and discussed in this volume. In addition, it demonstrates the applications of ESR in food and medical sciences, i.e., the estimation and characterization of the antioxidant ability of foods and food components and the elucidation of the underlying chemical mechanisms.
Author: Hiroaki Ohya-Nishiguchi Publisher: Birkhäuser ISBN: 3034890591 Category : Science Languages : en Pages : 337
Book Description
This book is based on two keywords: Bioradical and ESR. Bioradical is a newly coined word which encompasses paramagnetic species in biological systems, such as active oxygen radicals and transition metal ions. Research on the structure and function of bioradicals has been attrac ting growing attention in the field of biological science, and comprehensive investigations from many fields are helping to understand the real features of these species. ESR spectroscopy also has interdisciplinary features in that its techniques have been applied to many fields, ranging from physics to medicine. It was our hope, therefore, that this book would help to clarify many aspects of bioradicals and that significant progress would be achieved in combining basic research from many different fields. This book arises from the First International Conference on Bioradicals Detected by ESR Spectroscopy (ICBES), which was held in Yamagata, a city in the Yamagata Prefecture of Japan, in 1994. About 300 participants from 16 different countries attended this conference, and about 170 papers were presented. This book is a collection of contributions from the conference and also contains eleven chapters selected by the editorial board, based on sugges tions from the members of the international editorial board of ICBES. The Yamagata Technopolis Foundation is developing a biomedical technology for the 21st century based on life science fused with material and physical science. Based on such a techno logy, the Foundation plans to share its fruits all over the world.
Author: Ashutosh Kumar Shukla Publisher: Springer ISBN: 9811322309 Category : Medical Languages : en Pages : 221
Book Description
This book examines various applications of electron spin resonance spectroscopy (ESR) in medicine, covering topics such as interactions between blood and nanoparticles, physical intricacy of HbNO complexes, parasitic diseases, oxidative stress measurement, polymerization of resinous materials used in dentistry, tooth dosimetry and dermatological applications. Instead of providing mathematical details, it focuses on the applications and data interpretation of ESR as an emerging tool. This book is intended for students and researchers interested in the field of ESR applications in translational research and medicine.
Author: A. Favier Publisher: Birkhäuser ISBN: 3034890745 Category : Science Languages : en Pages : 314
Book Description
"Oxidative stress" is used as the generic term describing the involve ment of reactive oxygen species in various human diseases. The scope of such a topic is becoming increasingly wide. The recent interest in radicals such as nitric oxide and the discovery of new mechanisms such as the effect of free radicals on redox sensitive proteins and genes are enlarging our understanding of the physiological role of free radicals. Oxidative stress is involved in numerous pathological. processes such as ageing, respiratory or cardiovascular diseases, cancer, neurological pathologies such as dementia or Parkinson's disease. It still remains difficult, however, to demonstrate by chemical measurement the in vivo production of free radicals and even more to realise their speciation. Therefore, the development of new tools and indicators is engrossing many researchers working in this field. Reliable indicators are abso lutely necessary not only to monitor the evolution of oxidative stress in patients but also to evaluate the efficiency of new antioxidant treat ments. The French Free radical club of Grenoble, the CERLIB has been involved for many years in the organisation of international training programs on methodology, in order to provide both theoretical and practical help to researchers from various countries. Such training sessions have been highly successful and participants value the oppor tunity to learn reliable techniques. This positive echo explains why the researchers of CERLIB decided, with the help of Prof. Dr. B. Kalyanaraman, to publish selected techniques on free radical re search.
Author: Christopher J. Bender Publisher: Springer Science & Business Media ISBN: 144198951X Category : Medical Languages : en Pages : 437
Book Description
Electron magnetic resonance spectroscopy is undergoing something akin to a renaissance that is attributable to advances in microwave circuitry and signal processing software. EPR: Instrumental Methods is a textbook that brings the reader up to date on these advances and their role in providing better experimental techniques for biological magnetic resonance. Chapters in this book guide the reader from basic principles of spectrometer design through the advanced methods that are providing new vistas in disciplines such as oximetry, imaging, and structural biology. Key Features: Spectrometer design, particularly at low frequencies (below X-band), Design of spectrometer components unique to ENDOR and ESEEM, Optimization of EMR spectrometer sensitivity spanning many octaves, Algorithmic approach to spectral parameterization, Application of Fourier Methods to polymer conformation, oximetry, and imaging.
Author: Jens Thiele Publisher: Karger Medical and Scientific Publishers ISBN: 3805571321 Category : Medical Languages : en Pages : 202
Book Description
Are free radicals and reactive oxygen species relevant to dermatopathology? Do antioxidants protect against free-radical-mediated cutaneous diseases and aging? To these and further current questions in the rapidly progressing field of basic and applied skin research, this up-to-date volume provides a scientific basis. It presents state-of-the-art reviews on the progress in detection of free radicals and antioxidants and their responses to environmental oxidative stressors. Furthermore, several expert contributions focus on the exciting developments in oxidative DNA damage and UVB- and UVA-induced signal transduction in skin. Finally, information is given on new antioxidant protection strategies against skin carcinogenesis and skin aging which may be fundamental for the pharmaceutical or skin-care products of tomorrow. Due to its unique and up-to-date collection of state-of-the-art contributions by many of the world's leading scientists in the field, this book will be essential reading for dermatologists, cosmetologists, pharmacologists and environmental toxicologists.
Author: Lawrence Berliner Publisher: Springer Science & Business Media ISBN: 0306456443 Category : Science Languages : en Pages : 435
Book Description
We present here the second issue devoted entirely to the spin-labeling technique as part of Biological Magnetic Resonance. Volume 14 commemorates a modifi- tion in our editorial policy with the retirement of my esteemed coeditor, Jacques Reuben. From thisjuncture into the future, each issue will focus on some special topic in magnetic resonance. Each volume will be organized in most cases by guest editors, for example forthcoming issues will address the following topics: in vivo magnetic resonance (P. Robitaille and L. J. Berliner, eds. ) Modern techniques in proton NMR ofproteins (R. Krishna and L. J. Berliner, eds. ) Instrumental techniques of EPR (C. Bender and L. J. Berliner, eds. ) Thecurrent volume, Spin Labeling: The NextMillennium, presents an excellent collection of techniques and applications that evolved during the past decade since the last volume, volume 8 (1989). Someobvious omissions, such as multiquantum EPR and very high-frequency FT-ESR were unfortunately not possible for this volume. Perhaps they will appear in Spin Labeling: 2001. Lastly it is a pleasure to honor two scientists whose contributions were both pioneering and pivotal to the spin label technique: Professor Eduard G. Rozantsev (Moscow), whose synthetic feats in nitroxyl chemistry set the broad stage for a versatile catalog of labels; and Professor Harden M. McConnell, last year's Int- national ESR (EPR) Society Gold Medalist, who conceived and developed the spin label technique to address many biological problems (proteins, enzymes, m- branes, cells, immune response, etc. ). Lawrence J.
Author: Lawrence J. Berliner Publisher: Springer Science & Business Media ISBN: 0306470721 Category : Science Languages : en Pages : 435
Book Description
We present here the second issue devoted entirely to the spin-labeling technique as part of Biological Magnetic Resonance. Volume 14 commemorates a modifi- tion in our editorial policy with the retirement of my esteemed coeditor, Jacques Reuben. From thisjuncture into the future, each issue will focus on some special topic in magnetic resonance. Each volume will be organized in most cases by guest editors, for example forthcoming issues will address the following topics: in vivo magnetic resonance (P. Robitaille and L. J. Berliner, eds. ) Modern techniques in proton NMR ofproteins (R. Krishna and L. J. Berliner, eds. ) Instrumental techniques of EPR (C. Bender and L. J. Berliner, eds. ) Thecurrent volume, Spin Labeling: The NextMillennium, presents an excellent collection of techniques and applications that evolved during the past decade since the last volume, volume 8 (1989). Someobvious omissions, such as multiquantum EPR and very high-frequency FT-ESR were unfortunately not possible for this volume. Perhaps they will appear in Spin Labeling: 2001. Lastly it is a pleasure to honor two scientists whose contributions were both pioneering and pivotal to the spin label technique: Professor Eduard G. Rozantsev (Moscow), whose synthetic feats in nitroxyl chemistry set the broad stage for a versatile catalog of labels; and Professor Harden M. McConnell, last year's Int- national ESR (EPR) Society Gold Medalist, who conceived and developed the spin label technique to address many biological problems (proteins, enzymes, m- branes, cells, immune response, etc. ). Lawrence J.
Author: Wilfred Raymond Hagen Publisher: CRC Press ISBN: 9781420059588 Category : Science Languages : en Pages : 248
Book Description
Comprehensive, Up-to-Date Coverage of Spectroscopy Theory and its Applications to Biological Systems Although a multitude of books have been published about spectroscopy, most of them only occasionally refer to biological systems and the specific problems of biomolecular EPR (bioEPR). Biomolecular EPR Spectroscopy provides a practical introduction to bioEPR and demonstrates how this remarkable tool allows researchers to delve into the structural, functional, and analytical analysis of paramagnetic molecules found in the biochemistry of all species on the planet. A Must-Have Reference in an Intrinsically Multidisciplinary Field This authoritative reference seamlessly covers all important bioEPR applications, including low-spin and high-spin metalloproteins, spin traps and spin lables, interaction between active sites, and redox systems. It is loaded with practical tricks as well as do’s and don’ts that are based on the author’s 30 years of experience in the field. The book also comes with an unprecedented set of supporting software designed with simple graphical user interfaces that allow readers to tackle problems they will likely encounter when engaged in spectral analysis. Breaking with convention, the book broaches quantum mechanics from the perspective of biological relevance, emphasizing low-symmetry systems. This is a necessary approach since paramagnets in biomolecules typically have no symmetry. Where key topics related to quantum mechanics are addressed, the book offers a rigorous treatment in a style that is quick-to-grasp for the non expert. Biomolecular EPR Spectroscopy is a practical, all-inclusive reference sure to become the industry standard.
Author: Lawrence J. Berliner Publisher: Springer Science & Business Media ISBN: 1461500613 Category : Medical Languages : en Pages : 670
Book Description
In Vivo EPR (ESR) is a textbook on this relatively new subject in biomedical electron spin resonance. While a few chapters have appeared in special topics volumes in this series, this book covers the principles and theory, instrumentation as well as the latest applications at the time of its writing. The authors are world-renowned experts and pioneers in their fields. This book is divided into two major sections dealing with theory and instrumentation, and aspects of biochemistry, in vitro and in vivo applications. A significant amount of detail is devoted to clinical applications and the problems and pitfalls encountered in in vivo spectroscopy and imaging. Key Features: -History of In Vivo EPR, -Principles of Imaging-Theory and Instrumentation, -Time-domain Radio Frequency EPR Imaging, -The Measurement of Oxygen In Vivo Using In Vivo EPR Techniques, -Potential Medical (Clinical) Applications of EPR, -Combining NMR and EPR/ESR for In Vivo Experiments.
Author: Hiroaki Ohya-Nishiguchi
Author: Hiroaki Ohya-Nishiguchi
Author: Hiroaki Ohya-Nishiguchi
Author: Ashutosh Kumar Shukla
Author: A. Favier
Author: Christopher J. Bender
Author: Jens Thiele
Author: Lawrence Berliner
Author: Lawrence J. Berliner
Author: Wilfred Raymond Hagen
Author: Lawrence J. Berliner