Neuropathic Pain

Neuropathic Pain PDF Author: Cory Toth
Publisher: Cambridge University Press
ISBN: 1107470439
Category : Medical
Languages : en
Pages : 385

Book Description
Central or peripheral neuropathic pain can be caused by a wide range of injuries, infections and diseases such as: spinal cord injury, multiple sclerosis, stroke, herpes zoster, diabetes and cancer. Many of these pain syndromes are difficult to treat, representing a challenge for many neurologists not routinely trained in pain management. Written by an international team of experts in the field, Neuropathic Pain: Causes, Management and Understanding gives readers an in-depth understanding of the multitude of conditions causing neuropathic pain. Epidemiology, clinical diagnosis, pathophysiology, outcome measurement and the best evidence-based management of individual and general neuropathic pain conditions are also described in depth. A unique chapter, written from a patient's viewpoint, gives new insight into how chronic neuropathic pain affects the lives of those patients with the condition. This book is essential reading for all pain specialists, neurologists, psychiatrists and anesthesiologists who wish to better understand their patients' neuropathic pain.

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease PDF Author: Robert Fitridge
Publisher: University of Adelaide Press
ISBN: 1922064009
Category : Medical
Languages : en
Pages : 589

Book Description
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Challenging Neuropathic Pain Syndromes

Challenging Neuropathic Pain Syndromes PDF Author: Mitchell Freedman
Publisher: Elsevier Health Sciences
ISBN: 0323496075
Category : Medical
Languages : en
Pages : 350

Book Description
Get a quick, expert overview of the many key facets of neuropathic pain syndromes with this concise, practical resource by Drs. Mitchell Freedman, Jeff Gehret, George Young, and Leonard Kamen. This easy-to-read reference presents a summary of today’s best evaluation methods and evidence-based treatment options for complex regional pain syndrome as well as other challenging syndromes. Covers key topics such as: Evidence Based Approach to Many Uncommon and Difficult Neuropathic Pain Syndromes Review of Pathophysiology of Pain Approach to Chronic Pain Syndromes Work Up and Treatments for Complex Regional Pain Syndromes Consolidates today’s available information and experience in this multifaceted area into one convenient resource.

Neuropathic Pain

Neuropathic Pain PDF Author: David M. Simpson
Publisher: Oxford University Press
ISBN: 0195394704
Category : Medical
Languages : en
Pages : 544

Book Description
The incidence of neuropathic pain continues to rise, yet it is an affliction often misdiagnosed or inadequately treated. Although in recent years considerable research has been dedicated to understanding its mechanisms, there have been few advances in treatment. The contributors to this book are internationally renowned leaders in the fields of peripheral neuropathy and neuropathic pain. They discuss clinical approaches to diagnosis and treatment of neuropathic pain, its underlying mechanisms, and strategies for prevention. In addition, chapters cover timely issues, including legal and ethical concerns surrounding pain treatment, the status of clinical trial methods, and educational efforts. Comprehensive yet concise, this book serves as a guide for diagnostic approaches and treatment of neuropathic pain for the student, resident, practicing physician, researcher, and specialist.

Neuropathic Pain

Neuropathic Pain PDF Author: Jianguo Cheng
Publisher: Oxford University Press
ISBN: 0190298359
Category : Medical
Languages : en
Pages : 337

Book Description
Neuropathic pain is one of the most common, most debilitating, most costly, and most difficult to treat categories of chronic pain conditions that are characterized by a lesion or disease of the somatosensory nervous system. Managing neuropathic pain is challenging and requires skillful assessment and comprehensive and integrated treatment strategies that are mechanism-guided, evidence-based, and individualized. However, these critical and integral elements are very fragmented in the current literature. The mechanistic understanding of neuropathic pain is typically found in basic research articles. Clinical research evidence is presented in forms of clinical trials with emphasis on minimizing biases such as those from patient selection and assessment. Individualized considerations for each patient are usually presented in case reports and problem-based learning discussions. This book overcomes these barriers and integrates all the critical elements around individual patient care into a coherent management strategy that is practical and applicable to daily clinical practice. Rather than compiling what have been published in the literature, this work emphasizes on identifying and highlighting the key points or findings that guide decision-making in clinical practice. It integrates the key points around a typical case scenario that not only represents the core of the diagnostic and therapeutic processes but also allows introduction and differentiation of painful conditions that bare similarities with the case in hand. The overarching goal is to improve clinical outcomes through better understanding of the mechanisms, more accurate diagnosis, and wiser and more comprehensive treatment strategies.

Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Multiple Sclerosis

Multiple Sclerosis PDF Author: Ian S. Zagon
Publisher:
ISBN: 9780994438133
Category :
Languages : en
Pages : 137

Book Description


Holland-Frei Cancer Medicine

Holland-Frei Cancer Medicine PDF Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2008

Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Pain Care Essentials and Innovations

Pain Care Essentials and Innovations PDF Author: Sanjog Pangarkar
Publisher: Elsevier Health Sciences
ISBN: 0323722172
Category : Medical
Languages : en
Pages : 296

Book Description
Covering the newest trends and treatments in pain care, as well as the pain treatment strategies that have been successfully employed in the past, Pain Care Essentials and Innovations brings you fully up to date with effective treatments for acute and chronic pain. It offers expert guidance on both interventional and non-interventional strategies, provided by respected academic physiatrists who practice evidence-based medicine at UCLA and an ACGME-accredited rehabilitation and pain program. Covers cannabinoids in pain care, novel therapeutics in pain medicine, and integrative care in pain management. Discusses relevant basic science, psychological aspects of pain care, opioids and practice guidelines, geriatric pain management, and future research in the field. Consolidates today’s available information and guidance into a single, convenient resource.

Small Fiber Neuropathy and Related Syndromes: Pain and Neurodegeneration

Small Fiber Neuropathy and Related Syndromes: Pain and Neurodegeneration PDF Author: Sung-Tsang Hsieh
Publisher: Springer
ISBN: 981133546X
Category : Medical
Languages : en
Pages : 184

Book Description
This book provides comprehensive coverage of small fiber neuropathy (SFN), from diagnosis to therapy. It focuses on nerve degeneration and neuropathic pain, and their underlying pathology, physiology, psychophysics, genetics and imaging. In particular, this book describes and discusses the major advances in diagnostic techniques for assessing SFN. These include skin biopsy, evoked potentials, quantitative sensory testing and functional studies, as biomarkers of SFN. SFN is a common peripheral nerve disorder, but was often overlooked due to a lack of objective and specific diagnostic tests for the assessment of small nerve fibers. These fibers mediate thermal sensation, pain detection (nociception), and autonomic regulation. Major symptoms of SFN include neuropathic pain, impaired sensation and autonomic dysfunction. Neuropathic pain poses a diagnostic challenge to clinicians, an essential step for selecting appropriate treatment to relieve suffering. SFN frequently develops in systemic diseases such as diabetes mellitus, following chemotherapy, infections etc., or presents as a major feature of various genetic neuropathies (e.g. channelopathy and familial amyloidosis). In addition to describing these conditions which lead to SFN, this book also describes related syndromes of neurodegeneration and pain, including fibromyalgia, visceral pain and hypersensitivity. This definitive book covers both clinical aspects and research progress, which provides in-depth and up-to-date information on SFN. It would be immensely useful for clinicians, neurologists, neuroscientists, diabetologists, and pain specialists. Dr. Sung-Tsang Hsieh is a professor at Department of Neurology and Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taiwan. He is also the associate dean of College of Medicine, National Taiwan University, Taiwan. Dr. Praveen Anand is a professor at Department of Clinical Neurology and head of Centre for Clinical Translation, Hammersmith Hospital, UK. Dr. Christopher Gibbons is an associate professor of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, USA. Dr. Claudia Sommer is a professor of Neurology at the Department of Neurology, Würzburg University Hospital, Germany.