New Frontiers in Regenerative Medicine PDF Download

Author: M. Kusano
Publisher: Springer Science & Business Media
ISBN: 4431382089
Category : Medical
Languages : en
Pages : 164

View

Book Description
Rapid advances in stem cell biology have raised exciting possibilities of replacing damaged or lost tissues and cells by activation of in vitro-expanded stem cells or their progeny. This book examines many of the unresolved problems as well as future applications of regenerative medicine. In addition to animal experiments, results of research on human tissues and organs are included.

Author: Atta-ur- Rahman
Publisher: Bentham Science Publishers
ISBN: 1681085895
Category : Science
Languages : en
Pages : 263

View

Book Description
Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. This volume includes reviews on the following topics: -the role of microvesicles and exosomes in mesenchymal stem cell (MSCs) in treating diseases while overcoming side effects -alternative models for understanding cancer stem cell biology -stem cells treatments for orthopaedic injury and endocrine disorders -wound healing biomaterials -theoretical models of hematopoietic cell dynamics (with implications for bone marrow transplants)

Author: Alexander Battler
Publisher: Springer Science & Business Media
ISBN: 9781846286766
Category : Medical
Languages : en
Pages : 460

View

Book Description
Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.

Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681081830
Category : Science
Languages : en
Pages : 302

View

Book Description
Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as tumors, Alzheimer’s disease and related neurodegenerative diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. The second volume of this series features reviews on several key topics in this field including cardiac regeneration strategies, induced pluripotent stem cell therapeutics, stem cell therapy for peripheral nerve and cutaneous injuries, dental tissue regeneration, the potential of stem cell differentiation into ovarian cells and much more.

Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681087634
Category : Science
Languages : en
Pages : 260

View

Book Description
Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer’s disease and retinal disorders, among others, may well be addressed employing stem cell therapies and tissue regeneration techniques. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. This volume includes current literature on a variety of topics: -the utility of exogenous and endogenous neural stem cells in spinal cord injury -somatic cells for human induced pluripotent stem cells (iPSCs) -reactive oxygen species (ROS) mediated cellular signaling for stem cell differentiation -the therapeutic potential of microRNAs in cardiac diseases -stem cell therapy for the treatment of malaria

Author: Maria H. Santana
Publisher: Academic Press
ISBN: 0323904327
Category : Science
Languages : en
Pages : 615

View

Book Description
"Cell niches are present in several human body tissues as a dynamic microenvironment essential to modulate stem cells’ behavior in health, under injury, and in regenerative processes. The interplay between stem cells and their niche is necessary for sustaining tissues. The extracellular matrix (ECM) is the crucial component of the stem cell. It defines the architectural space, physical binding to the cell membrane, and interactions with the neighborhood cells and supports physical stress. Domains with nano or micrometric sizes define the surface and topology of the ECM, mediating cell interactions and macrophage recruitment to injured sites. Over the last two decades, the integration of biomedicine with other engineering and biomaterial sciences promoted the development of nanotechnology and regenerative medicine toward mimicking the specialized stem cell niches to treat diseases with less invasive and efficient therapies. Innovative approaches in nanotechnology, such as targeting the immunological system, transporting drugs across blood–brain/BBB and blood–retinal barriers/BRB, directing active moiety to specific disease location/organs, encapsulation of multiple components, and promoting signalization and pathway-specific surfaces for cell interactions and growth, are indeed promising. On the other side, developments of biomaterial scaffolds to mimic the cell niches for interactions with stem cells in vitro or in vivo have tremendous potential. The three-dimensional printing technology offers a base for a wide array of applications, for example, developing tissue constructs, mimetic organs, organoids, and organ-on-a-chip, thus avoiding the differences between animal model species and humans. Aiming closer to the natural environments, fresh autologous products from the blood, such as platelet-rich plasma (PRP), contain platelets and leukocytes, providing growth factors, cytokines, and proteins for the resident stem cells in the stages of regeneration. PRP also provides pain relief, reducing disabilities in elderly or diseased people. This book brings thought-provoking multidisciplinary topics on the diverse aspects of basic and applied sciences. The prime focus of the compilation is to understand the challenges researchers encounter in combining nanotechnology and regenerative medicine, ultimately integrating both disciplines for the benefit of the patient and offering them a ray of hope to be cured. Presents multi-disciplined knowledge on bench-to-bedside application of nanotechnology in regenerative medicines Highlights the fundamentals, frontiers, limitations, and challenges faced by regenerative medicines Exhibits synergy of biotechnology, nanomedicine, biomedicine, chemical-material engineering, pharmaceutical technology, and applied medical sciences in success of regenerative medicines

Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 9811464685
Category : Science
Languages : en
Pages : 172

View

Book Description
Frontiers in Stem Cell and Regenerative Medicine Research Volume 10 [Edited for Volume 10] Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer’s disease and retinal disorders, among others, may well be addressed employing stem cell therapies and tissue regeneration techniques. Frontiers in Stem Cell and Regenerative Medicine Research brings updates on multidisciplinary topics relevant to stem cell research and their application in regenerative medicine. The series is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. Volume 10 includes 5 chapters on these topics: -Novel drugs and their stem cell-based targets for osteoporosis: challenges and proceedings -The role of cancer stem cells in disease progression and therapy resistance -Stem cells from human exfoliated deciduous teeth in tissue regeneration -The fate of toxicological studies: from animal models to stem cell-based methods -Effect of material properties on differentiation of mesenchymal stem cells

Author: Atta-ur-Rahman
Publisher:
ISBN: 9781681085906
Category :
Languages : en
Pages :

View

Book Description
Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. This volume includes reviews on the following topics: -the role of microvesicles and exosomes in mesenchymal stem cell (MSCs) in treating diseases while overcoming side effects -alternative models for understanding cancer stem cell biology -stem cells treatments for orthopaedic injury and endocrine disorders -wound healing biomaterials -theoretical models of hematopoietic cell dynamics (with implications for bone marrow transplants)

Author: Sheldon Krimsky
Publisher: Columbia University Press
ISBN: 0231539401
Category : Science
Languages : en
Pages : 280

View

Book Description
Stem cells and the emerging field of regenerative medicine are at the frontiers of modern medicine. These areas of scientific inquiry suggest that in the future, damaged tissue and organs might be repaired through personalized cell therapy as easily as the body repairs itself, revolutionizing the treatment of numerous diseases. Yet the use of stem cells is fraught with ethical and public policy dilemmas that challenge scientists, clinicians, the public health community, and people of good will everywhere. How shall we deal with these amazing biomedical advances, and how can we talk about potential breakthroughs with both moral and scientific intelligence? This book provides an innovative look at these vexing issues through a series of innovative Socratic dialogues that elucidate key scientific and ethical points in an approachable manner. Addressing the cultural and value issues underlying stem cell research while also educating readers about stem cells' biological function and medical applications, Stem Cell Dialogues features fictional characters engaging in compelling inquiry and debate. Participants investigate the scientific, political, and socioethical dimensions of stem cell science using actual language, analysis, and arguments taken from scientific, philosophical, and popular literature. Each dialogue centers on a specific, recognizable topic, such as the policies implemented by the George W. Bush administration restricting the use of embryonic stem cells; the potential role of stem cells in personalized medicine; the ethics of cloning; and the sale of eggs and embryos. Additionally, speakers debate the use of stem cells to treat paralysis, diabetes, stroke effects, macular degeneration, and cancer. Educational, entertaining, and rigorously researched (with 300 references to scientific literature), Stem Cell Dialogues should be included in any effort to help the public understand the science, ethics, and policy concerns of this promising field.

Author: Gustav Steinhoff
Publisher: Springer Science & Business Media
ISBN: 9048190754
Category : Medical
Languages : en
Pages : 1032

View

Book Description
Regenerative Medicine is a fastly emerging interdisciplinary field of research and clinical therapies on the repair, replacement or regeneration of cells, tissues or organs in congenital or acquired disease. This new field of research and clinical development focussing on stem cell science and regenerative biology is just starting to be the most fascinating and controversial medical development at the dawn of the 21st century. Viewing the great expectations to restructure and regenerate tissue, organs or organisms the current attempts of scientist and physicians are still in an early phase of development. This new textbook on “Regenerative Medicine – from protocol to patient” is aiming to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. The international leading experts from four continents describe the latest scientific and clinical knowledge of the field of “Regenerative Medicine”. The process of translating science of laboratory protocols into therapies is explained in sections on basic science, clinical translation, regulatory, ethical and industrial issues. The textbook is aiming to give the student, the researcher, the health care professional, the physician, and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practised therapies in Regenerative Medicine.