Open-Channel Microfluidics (Second Edition) PDF Download

Author: Jean (University of Washington) Berthier
Publisher: IOP ebooks
ISBN: 9780750355056
Category : Science
Languages : en
Pages : 0

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Book Description
The development of open microfluidics is relatively recent and is an emerging sub-domain of capillarity, with many applications. This second edition research text presents the recent advances in open microfluidics, the science that describes capillary microflows guided by solid structures and partly open to the surrounding air.

Author: Jean Berthier
Publisher: Morgan & Claypool Publishers
ISBN: 1643276646
Category : Technology & Engineering
Languages : en
Pages : 171

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Book Description
Open microfluidics, the study of microflows having a boundary with surrounding air, encompasses different aspects such as paper or thread-based microfluidics, droplet microfluidics and open-channel microfluidics. Open-channel microflow is a flow at the micro-scale, guided by solid structures, and having at least a free boundary (with air or vapor) other than the advancing meniscus. This book is devoted to the study of open-channel microfluidics which (contrary to paper or thread or droplet microfluidics) is still very sparsely documented, but bears many new applications in biology, biotechnology, medicine, material and space sciences. Capillarity being the principal force triggering an open microflow, the principles of capillarity are first recalled. The onset of open-channel microflow is next analyzed and the fundamental notion of generalized Cassie angle (the apparent contact angle which accounts for the presence of air) is presented. The theory of the dynamics of open-channel microflows is then developed, using the notion of averaged friction length which accounts for the presence of air along the boundaries of the flow domain. Different channel morphologies are studied and geometrical features such as valves and capillary pumps are examined. An introduction to two-phase open-channel microflows is also presented showing that immiscible plugs can be transported by an open-channel flow. Finally, a selection of interesting applications in the domains of space, materials, medicine and biology is presented, showing the potentialities of open-channel microfluidics.

Author: Berthier Jean
Publisher:
ISBN: 9781643276632
Category :
Languages : en
Pages : 0

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Book Description

Author: Jean Berthier
Publisher: John Wiley & Sons
ISBN: 1118720822
Category : Science
Languages : en
Pages : 384

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Book Description
Open microfluidics or open-surface is becoming fundamental in scientific domains such as biotechnology, biology and space. First, such systems and devices based on open microfluidics make use of capillary forces to move fluids, without any need for external energy. Second, the "openness" of the flow facilitates the accessibility to the liquid in biotechnology and biology, and reduces the weight in space applications. This book has been conceived to give the reader the fundamental basis of open microfluidics. It covers successively The theory of spontaneous capillary flow, with the general conditions for spontaneous capillary flow, and the dynamic aspects of such flows. The formation of capillary filaments which are associated to small contact angles and sharp grooves. The study of capillary flow in open rectangular, pseudo-rectangular and trapezoidal open microchannels. The dynamics of open capillary flows in grooves with a focus on capillary resistors. The case of very viscous liquids is analyzed. An analysis of suspended capillary flows: such flows move in suspended channels devoid of top cover and bottom plate. Their accessibility is reinforced, and such systems are becoming fundamental in biology. An analysis of “rails” microfluidics, which are flows that move in channels devoid of side walls. This geometry has the advantage to be compatible with capillary networks, which are now of great interest in biotechnology, for molecular detection for example. Paper-based microfluidics where liquids wick flat paper matrix. Applications concern bioassays such as point of care devices (POC). Thread-based microfluidics is a new domain of investigation. It is seeing presently many new developments in the domain of separation and filtration, and opens the way to smart bandages and tissue engineering. The book is intended to cover the theoretical aspects of open microfluidics, experimental approaches, and examples of application.

Author: Patrick Tabeling
Publisher: Oxford University Press
ISBN: 0192660039
Category : Science
Languages : en
Pages : 481

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Book Description
The second edition of Introduction to Microfluidics captures all the new exciting developments in the field of microfluidics over the last twenty years. While maintaining the same clear structure, and accessible explanations of the basic theory, this new edition is a complete revision of the first edition and makes use of the considerable data collected in the field over the last two decades. The book describes the applications, the market, and attempts to envision the future of microfluidics. It covers the physics of miniaturization, the hydrodynamics of microfluidics in channels and with droplets, transport phenomena in microsystems, electrokinetic phenomena, and an introduction to microfabrication. The basic principles are explored in depth and with rigor, and their main applications are clearly presented. Many examples are provided and discussed simply, most often from a physical perspective, and the book includes 415 figures and 600 references. Offering a cross-disciplinary view of the field embracing biological, chemical, physical and engineering perspectives, this book is an ideal resource for students and researchers at any level.

Author: Jing Jei Lee
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description
This dissertation discusses advancements in open channel microfluidics, the design and fabrication of open channels and capillary pumps, and methods to manipulate open channels. An open droplet-based microfluidics platform is demonstrated with promising future applications. Additionally, an expression to measure the velocity of capillary flow in an open channel and design guidelines for an efficient capillary pump are presented.Chapter 1 discusses the field of microfluidics and the advantages of such platforms. The fundamentals of open microfluidics is presented along with the benefits of open channel systems. Capillary flow is discussed, and the necessary considerations for fabrication of channels to ensure that the fluid in the system is driven by capillary means is provided. Droplet-based microfluidics is a large subfield of microfluidics, which is briefly reviewed, and a need for further fundamental and applied work using droplet-based systems which are completely driven by capillary flow is discussed. Finally, capillary pumps provide a solution to the inherent decrease of velocity (and flow rate) observed in channels driven by capillary flow. Chapter 2 introduces droplet-based microfluidics where droplets are formed in an open channel that is completely driven by capillary means. Our work represents the first time that this phenomenon was observed and studied. The interaction that exists between a droplet and the surrounding phase is described in detail. Chapter 3 explores fundamental microfluidic features in open channels: droplet splitting, multiple droplets, and droplet merging. An example of an open platform that enables users to manipulate droplets on the same chip is presented. Chapter 4 investigates capillary flow in an open channel, and an expression to measure velocity derived from the Lucas-Washburn-Rideal law is presented. The capillary flow in bifurcations and networks of open channels are studied. Chapter 5 investigates the theory of open capillary pumps to alleviate the inherent decrease of velocity and flow rate during capillary flow. Design guidelines of an efficient open capillary pump are discussed. Chapter 6 concludes the thesis with an overall perspective of the field and other experimental proposals to improve the overall design of open channels and capillary pumps and to enable applications with the platform.

Author: Yu Song
Publisher: John Wiley & Sons
ISBN: 3527341064
Category : Science
Languages : en
Pages : 576

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Book Description
The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.

Author: Dongqing Li
Publisher: Springer Science & Business Media
ISBN: 0387324682
Category : Technology & Engineering
Languages : en
Pages : 2242

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Book Description
Covering all aspects of transport phenomena on the nano- and micro-scale, this encyclopedia features over 750 entries in three alphabetically-arranged volumes including the most up-to-date research, insights, and applied techniques across all areas. Coverage includes electrical double-layers, optofluidics, DNC lab-on-a-chip, nanosensors, and more.

Author: Emmanuel Delamarche
Publisher: John Wiley & Sons
ISBN: 3527340386
Category : Technology & Engineering
Languages : en
Pages : 440

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Book Description
Summarizing the latest trends and the current state of this research field, this up-to-date book discusses in detail techniques to perform localized alterations on surfaces with great flexibility, including microfluidic probes, multifunctional nanopipettes and various surface patterning techniques, such as dip pen nanolithography. These techniques are also put in perspective in terms of applications and how they can be transformative of numerous (bio)chemical processes involving surfaces. The editors are from IBM Zurich, the pioneers and pacesetters in the field at the forefront of research in this new and rapidly expanding area.

Author: Henrik Bruus
Publisher: Oxford University Press
ISBN: 0191528587
Category : Science
Languages : en
Pages :

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Book Description
Microfluidics is a young and rapidly expanding scientific discipline, which deals with fluids and solutions in miniaturized systems, the so-called lab-on-a-chip systems. It has applications in chemical engineering, pharmaceutics, biotechnology and medicine. As the lab-on-a-chip systems grow in complexity, a proper theoretical understanding becomes increasingly important. The basic idea of the book is to provide a self-contained formulation of the theoretical framework of microfluidics, and at the same time give physical motivation and examples from lab-on-a-chip technology. After three chapters introducing microfluidics, the governing equations for mass, momentum and energy, and some basic flow solutions, the following 14 chapters treat hydraulic resistance/compliance, diffusion/dispersion, time-dependent flow, capillarity, electro- and magneto-hydrodynamics, thermal transport, two-phase flow, complex flow patterns and acousto-fluidics, as well as the new fields of opto- and nano-fluidics. Throughout the book simple models with analytical solutions are presented to provide the student with a thorough physical understanding of order of magnitudes and various selected microfluidic phenomena and devices. The book grew out of a set of well-tested lecture notes. It is with its many pedagogical exercises designed as a textbook for an advanced undergraduate or first-year graduate course. It is also well suited for self-study.