Permeability and Stability of Lipid Bilayers PDF Download

Author: E. Anibal Disalvo
Publisher: CRC Press
ISBN: 1351425382
Category : Science
Languages : en
Pages : 445

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Book Description
This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It begins by characterizing bilayers structurally, using X-ray diffraction, and then mechanically by measuring elastic moduli and mechanisms of failure. Emphasis is placed on the stability and mechanical properties of plant membranes that are subject to very large osmotic and thermal stresses. Using this information, the transport of molecules of increasing complexity across bilayers is analyzed.

Author: E. Anibal Disalvo
Publisher: CRC Press
ISBN: 1351425390
Category : Science
Languages : en
Pages : 288

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Book Description
This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It begins by characterizing bilayers structurally, using X-ray diffraction, and then mechanically by measuring elastic moduli and mechanisms of failure. Emphasis is placed on the stability and mechanical properties of plant membranes that are subject to very large osmotic and thermal stresses. Using this information, the transport of molecules of increasing complexity across bilayers is analyzed.

Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0

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Book Description

Author: William Stillwell
Publisher: Newnes
ISBN: 0080931286
Category : Science
Languages : en
Pages : 378

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Book Description
An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. Brings together different facets of membrane research in a universally understandable manner Emphasis on the historical development of the field Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport.

Author: Thomas Heimburg
Publisher: John Wiley & Sons
ISBN: 3527611606
Category : Science
Languages : en
Pages : 378

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Book Description
An overview of recent experimental and theoretical developments in the field of the physics of membranes, including new insights from the past decade. The author uses classical thermal physics and physical chemistry to explain our current understanding of the membrane. He looks at domain and 'raft' formation, and discusses it in the context of thermal fluctuations that express themselves in heat capacity and elastic constants. Further topics are lipid-protein interactions, protein binding, and the effect of sterols and anesthetics. Many seemingly unrelated properties of membranes are shown to be intimately intertwined, leading for instance to a coupling between membrane state, domain formation and vesicular shape. This also applies to non-equilibrium phenomena like the propagation of density pulses during nerve activity. Also included is a discussion of the application of computer simulations on membranes. For both students and researchers of biophysics, biochemistry, physical chemistry, and soft matter physics.

Author: A. Leitmannova Liu
Publisher: Elsevier
ISBN: 9780080461991
Category : Science
Languages : en
Pages : 370

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Book Description
The lipid bilayer is central to life, as all living organisms possess a lipid bilayer structure, thereby underlying the lipid bilayer principle of biomembranes. The lipid bilayer principle and its applications are the main theme of this new book series. This new series on bilayer lipid membranes (BLMs and liposomes) include invited chapters on a broad range of topics, from theoretical investigations, specific studies, experimental methods, to practical applications. Written for newcomers, experienced scientists, and those who are not familiar with these specific research areas, the Series covers all aspects of lipid bilayer investigations, both fundamental and applied. * Covers a broad range of topics ranging from theoretical research, specific studies, experimental methods, to practical applications * Authoritative timely reviews by experts in this field * Indispensable source of information for new scientists

Author: A. Leitmannova Liu
Publisher: Academic Press
ISBN: 9780080888668
Category : Science
Languages : en
Pages : 206

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Book Description
Advances in Planar Lipid Bilayers and Liposomes, Volume 10, continues to include invited chapters on a broad range of topics, covering the main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group. Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the further development of this interdisciplinary field worldwide. * Incorporates contributions from newcomers and established and experienced researchers * Explores the planar lipid bilayer systems and spherical liposomes from both theoretical and experimental perspectives * Serves as an indispensable source of information for new scientists

Author: H.T. Tien †
Publisher: Elsevier
ISBN: 0080539033
Category : Science
Languages : en
Pages : 1045

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Book Description
The lipid bilayer is the most basic structural element of cell membranes. A wide range of topics are covered in this volume, from the origin of the lipid bilayer concept, to current applications and experimental techniques. Each chapter in this volume is self-contained and describes a group's research, providing detailed methodology and key references useful for researchers. Lipid bilayer research is of great interest to many because of it's interdisciplinary nature. · Provides an overview of decades of research on the lipid bilayer· 38 contributed chapters, by leading scientists, cover a wide range of topics in one authoritative volume· Book coincides with 40th anniversary of BLM

Author: Cyrus R. Safinya
Publisher: CRC Press
ISBN: 0429527810
Category : Medical
Languages : en
Pages : 800

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Book Description
This handbook provides a comprehensive overview of lipid membrane fundamentals and applications. It gives the fundamental physical and biochemical aspects of membrane-related processes in living cells, and then relates them to how scientists are building bioinspired, artifical membrane-based systems such as gene delivery vehicles and synthetic membrane interfaces. It highlights the driving mechanism behind lipid self-assembly, membrane shape evolution, and vesicle trafficing, as well as the role of lipid membrane composition in signalling and the structural aspects of membranes in cellular integrity. Key Features: Includes a broad overview on the role of lipids as structural components of membranes, energy storage molecules, and signaling molecules. Covers lipids in signaling and the role of lipids in everyday life, from diet and health to cosmetics and pharmaceuticals. Discusses applications in nanotechnology and biomedicine, including liposomes in drug discovery, lipids for in vivo therapeutics, lipid-based sensors, artificial biointerfaces, and synthetic polymers. Includes an exciting section that explores the practical use of Archae lipids, lipids and the origins of life, and future outlook for the field. This book is a great companion for professionals in physics, biochemistry, physical chemistry and material sciences.

Author: E. Anibal Disalvo
Publisher: Springer
ISBN: 3319190601
Category : Science
Languages : en
Pages : 284

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Book Description
This book is about the importance of water in determining the structure, stability and responsive behavior of biological membranes. Water confers to lipid membranes unique features in terms of surface and mechanical properties. The analysis of the hydration forces, plasticiser effects, controlled hydration, formation of microdomains of confined water suggests that water is an active constituent in a water-lipid system. The chapters describe water organization at the lipid membrane–water interphase, the water penetration, the long range water structure in the presence of lipid membranes by means of X-ray and neutron scattering, general polarization, fluorescent probes, ATR-FTIR and near infrared spectroscopies, piezo electric methods, computer simulation and surface thermodynamics. Permeation, percolation, osmotic stress, polarization, protrusion, sorption, hydrophobicity, density fluctuations are treated in detail in self-assembled bilayers. Studies in lipid monolayers show the correlation of surface pressure with water activity and its role in peptide and enzyme interactions. The book concludes with a discussion on anhydrobiosis and the effect of water replacement in microdomains and its consequence for cell function. New definitions of lipid/water interphases consider water not only as a structural-making solvent but as a mediator in signalling metabolic activity, modulating protein insertion and enzymatic activity, triggering oscillatory reactions and functioning of membrane bound receptors. Since these effects occur at the molecular level, membrane hydration appears fundamental to understand the behavior of nano systems and confined environments mimicking biological systems. These insights in structural, thermodynamical and mechanical water properties give a base for new paradigms in membrane structure and function for those interested in biophysics, physical chemistry, biology, bio and nano medicine, biochemistry, biotechnology and nano sciences searching for biotechnological inputs in human health, food industry, plant growing and energy conversion.